Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10039946HBVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS10040735HBVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS20001818HPVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS20010059HPVENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS44025444HTLV-1ENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TVIS44016388HTLV-1ENSG00000142319.19protein_codingSLC6A3NoNo6531Q01959
TCGA Plot Options
Drug Information
GeneSLC6A3
DrugBank IDDB01363
Drug NameEphedra sinica root
Target IDBE0000647
UniProt IDQ01959
Regulation Typenegative modulator
PubMed IDs15955613; 15189772; 12954796; 17209801; 10773193
CitationsSulzer D, Sonders MS, Poulsen NW, Galli A: Mechanisms of neurotransmitter release by amphetamines: a review. Prog Neurobiol. 2005 Apr;75(6):406-33.@@Wee S, Ordway GA, Woolverton WL: Reinforcing effect of pseudoephedrine isomers and the mechanism of action. Eur J Pharmacol. 2004 Jun 16;493(1-3):117-25.@@Rothman RB, Vu N, Partilla JS, Roth BL, Hufeisen SJ, Compton-Toth BA, Birkes J, Young R, Glennon RA: In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates. J Pharmacol Exp Ther. 2003 Oct;307(1):138-45. Epub 2003 Sep 3.@@Fleckenstein AE, Volz TJ, Riddle EL, Gibb JW, Hanson GR: New insights into the mechanism of action of amphetamines. Annu Rev Pharmacol Toxicol. 2007;47:681-98.@@Haughey HM, Brown JM, Wilkins DG, Hanson GR, Fleckenstein AE: Differential effects of methamphetamine on Na(+)/Cl(-)-dependent transporters. Brain Res. 2000 Apr 28;863(1-2):59-65.
GroupsNutraceutical
Direct Classification
SMILES
Pathways
PharmGKBPA164777031
ChEMBL