| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039946 | HBV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS10040735 | HBV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS20001818 | HPV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS20010059 | HPV | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS44025444 | HTLV-1 | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
| TVIS44016388 | HTLV-1 | ENSG00000142319.19 | protein_coding | SLC6A3 | No | No | 6531 | Q01959 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC6A3 |
|---|---|
| DrugBank ID | DB01104 |
| Drug Name | Sertraline |
| Target ID | BE0000647 |
| UniProt ID | Q01959 |
| Regulation Type | inhibitor |
| PubMed IDs | 9537821; 18664165; 17187269; 15181382; 9808077 |
| Citations | Tatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.@@Ghanizadeh A: Sertraline-associated hair loss. J Drugs Dermatol. 2008 Jul;7(7):693-4.@@Lemke MR: [Antidepressant effects of dopamine agonists. Experimental and clinical findings]. Nervenarzt. 2007 Jan;78(1):31-8.@@Nemeroff CB, Owens MJ: Pharmacologic differences among the SSRIs: focus on monoamine transporters and the HPA axis. CNS Spectr. 2004 Jun;9(6 Suppl 4):23-31.@@Goodnick PJ, Goldstein BJ: Selective serotonin reuptake inhibitors in affective disorders--I. Basic pharmacology. J Psychopharmacol. 1998;12(3 Suppl B):S5-20. |
| Groups | Approved |
| Direct Classification | Tametralines |
| SMILES | CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA451333 |
| ChEMBL | CHEMBL809 |
