| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30085618 | HIV | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042313 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042312 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NOS2 |
|---|---|
| DrugBank ID | DB03144 |
| Drug Name | N(5)-[(hydroxyamino)(imino)methyl]-L-ornithine |
| Target ID | BE0000005 |
| UniProt ID | P35228 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Arginine and derivatives |
| SMILES | N[C@@H](CCCNC(=N)NO)C(O)=O |
| Pathways | Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Ornithine Aminotransferase Deficiency (OAT Deficiency); Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Hyperprolinemia Type I; Hyperprolinemia Type II; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Arginine and Proline Metabolism; Hyperornithinemia with Gyrate Atrophy (HOGA); Prolinemia Type II; L-Arginine:Glycine Amidinotransferase Deficiency; Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency |
| PharmGKB | |
| ChEMBL | CHEMBL260629 |
