| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30085618 | HIV | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042313 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042312 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NOS2 |
|---|---|
| DrugBank ID | DB01017 |
| Drug Name | Minocycline |
| Target ID | BE0000005 |
| UniProt ID | P35228 |
| Regulation Type | inhibitor |
| PubMed IDs | 11986668 |
| Citations | Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM: Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 2002 May 2;417(6884):74-8. |
| Groups | Approved; Investigational |
| Direct Classification | Tetracyclines |
| SMILES | [H][C@@]12CC3=C(C(O)=CC=C3N(C)C)C(=O)C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@]1([H])C2 |
| Pathways | Minocycline Action Pathway |
| PharmGKB | PA450519 |
| ChEMBL | CHEMBL1434 |
