| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30085618 | HIV | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042313 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
| TVIS44042312 | HTLV-1 | ENSG00000007171.19 | protein_coding | NOS2 | No | No | 4843 | P35228 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NOS2 |
|---|---|
| DrugBank ID | DB08814 |
| Drug Name | Triflusal |
| Target ID | BE0000005 |
| UniProt ID | P35228 |
| Regulation Type | agonist |
| PubMed IDs | 19465361; 9551715; 10998082; 16939630 |
| Citations | Anninos H, Andrikopoulos G, Pastromas S, Sakellariou D, Theodorakis G, Vardas P: Triflusal: an old drug in modern antiplatelet therapy. Review of its action, use, safety and effectiveness. Hellenic J Cardiol. 2009 May-Jun;50(3):199-207.@@Sanchez de Miguel L, Casado S, Farre J, Garcia-Duran M, Rico LA, Monton M, Romero J, Bellver T, Sierra MP, Guerra JI, Mata P, Esteban A, Lopez-Farre A: Comparison of in vitro effects of triflusal and acetysalicylic acid on nitric oxide synthesis by human neutrophils. Eur J Pharmacol. 1998 Feb 5;343(1):57-65.@@De Miguel LS, Jimenez A, Monton M, Farre J, Del Mar Arriero M, Rodriguez-Feo JA, Garcia-Canete J, Rico L, Gomez J, Nunez A, Casado S, Farre AL: A 4-trifluoromethyl derivative of salicylate, triflusal, stimulates nitric oxide production by human neutrophils: role in platelet function. Eur J Clin Invest. 2000 Sep;30(9):811-7.@@Gonzalez-Correa JA, De La Cruz JP: Triflusal: an antiplatelet drug with a neuroprotective effect? Cardiovasc Drug Rev. 2006 Spring;24(1):11-24. |
| Groups | Approved; Investigational |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1332032 |
