| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20054561 | HPV | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44014625 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44009369 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN1A |
|---|---|
| DrugBank ID | DB09088 |
| Drug Name | Amylocaine |
| Target ID | BE0009738 |
| UniProt ID | Q15858 |
| Regulation Type | blocker |
| PubMed IDs | 2157353; 22053156 |
| Citations | Butterworth JF 4th, Strichartz GR: Molecular mechanisms of local anesthesia: a review. Anesthesiology. 1990 Apr;72(4):711-34.@@Fozzard HA, Sheets MF, Hanck DA: The sodium channel as a target for local anesthetic drugs. Front Pharmacol. 2011 Nov 1;2:68. doi: 10.3389/fphar.2011.00068. eCollection 2011. |
| Groups | Approved; Withdrawn |
| Direct Classification | Benzoic acid esters |
| SMILES | CCC(C)(CN(C)C)OC(=O)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1740065 |
