| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20054561 | HPV | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44014625 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44009369 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN1A |
|---|---|
| DrugBank ID | DB00907 |
| Drug Name | Cocaine |
| Target ID | BE0004901 |
| UniProt ID | Q8IWT1 |
| Regulation Type | inhibitor |
| PubMed IDs | 9876137; 2155033 |
| Citations | Wright SN, Wang SY, Xiao YF, Wang GK: State-dependent cocaine block of sodium channel isoforms, chimeras, and channels coexpressed with the beta1 subunit. Biophys J. 1999 Jan;76(1 Pt 1):233-45.@@Crumb WJ Jr, Clarkson CW: Characterization of cocaine-induced block of cardiac sodium channels. Biophys J. 1990 Mar;57(3):589-99. doi: 10.1016/S0006-3495(90)82574-1. |
| Groups | Approved; Illicit |
| Direct Classification | Benzoic acid esters |
| SMILES | [H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)C1=CC=CC=C1)C(=O)OC)N2C |
| Pathways | Cocaine Action Pathway |
| PharmGKB | PA449072 |
| ChEMBL | CHEMBL370805 |
