| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20054561 | HPV | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44014625 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
| TVIS44009369 | HTLV-1 | ENSG00000144285.24 | protein_coding | SCN1A | No | No | 6323 | P35498 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN1A |
|---|---|
| DrugBank ID | DB00273 |
| Drug Name | Topiramate |
| Target ID | BE0009738 |
| UniProt ID | Q15858 |
| Regulation Type | inhibitor |
| PubMed IDs | 11948006; 15526956; 12861512 |
| Citations | Coppola G, Capovilla G, Montagnini A, Romeo A, Spano M, Tortorella G, Veggiotti P, Viri M, Pascotto A: Topiramate as add-on drug in severe myoclonic epilepsy in infancy: an Italian multicenter open trial. Epilepsy Res. 2002 Mar;49(1):45-8.@@Ceulemans B, Boel M, Claes L, Dom L, Willekens H, Thiry P, Lagae L: Severe myoclonic epilepsy in infancy: toward an optimal treatment. J Child Neurol. 2004 Jul;19(7):516-21.@@Nieto Barrera M, Candau Fernandez Mensaque R, Nieto Jimenez M: [Severe myoclonic epilepsy in infancy (Dravet's syndrome). Its nosological characteristics and therapeutic aspects]. Rev Neurol. 2003 Jul 1-15;37(1):64-8. |
| Groups | Approved |
| Direct Classification | Dioxolopyrans |
| SMILES | [H][C@@]12CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@]3([H])[C@]1([H])OC(C)(C)O2 |
| Pathways | |
| PharmGKB | PA451728 |
| ChEMBL | CHEMBL220492 |
