| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10014326 | HBV | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS30086512 | HIV | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS20022380 | HPV | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS20049966 | HPV | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS20049934 | HPV | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS44013458 | HTLV-1 | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
| TVIS44020347 | HTLV-1 | ENSG00000082175.16 | protein_coding | PGR | Yes | No | 5241 | P06401 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PGR |
|---|---|
| DrugBank ID | DB04787 |
| Drug Name | Tanaproget |
| Target ID | BE0000557 |
| UniProt ID | P06401 |
| Regulation Type | agonist |
| PubMed IDs | 10592235; 15937332 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Zhang Z, Olland AM, Zhu Y, Cohen J, Berrodin T, Chippari S, Appavu C, Li S, Wilhem J, Chopra R, Fensome A, Zhang P, Wrobel J, Unwalla RJ, Lyttle CR, Winneker RC: Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget. J Biol Chem. 2005 Aug 5;280(31):28468-75. Epub 2005 Jun 3. |
| Groups | Investigational |
| Direct Classification | Benzoxazines |
| SMILES | CN1C(=CC=C1C1=CC=C2NC(=S)OC(C)(C)C2=C1)C#N |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL539163 |
