Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10014326HBVENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS30086512HIVENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS20022380HPVENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS20049966HPVENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS20049934HPVENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS44013458HTLV-1ENSG00000082175.16protein_codingPGRYesNo5241P06401
TVIS44020347HTLV-1ENSG00000082175.16protein_codingPGRYesNo5241P06401
TCGA Plot Options
Drug Information
GenePGR
DrugBank IDDB06680
Drug NameAsoprisnil
Target IDBE0000557
UniProt IDP06401
Regulation Type
PubMed IDs15857972; 15714390
CitationsChwalisz K, Perez MC, Demanno D, Winkel C, Schubert G, Elger W: Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis. Endocr Rev. 2005 May;26(3):423-38. Epub 2005 Apr 27.@@Schubert G, Elger W, Kaufmann G, Schneider B, Reddersen G, Chwalisz K: Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs). Semin Reprod Med. 2005 Feb;23(1):58-73.
GroupsInvestigational
Direct ClassificationOxosteroids
SMILES[H]C(=N/O)C1=CC=C(C=C1)[C@@]1([H])C[C@@]2(C)[C@@]([H])(CC[C@]2(COC)OC)[C@]2([H])CCC3=CC(=O)CCC3=C12
Pathways
PharmGKB
ChEMBLCHEMBL267431