| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30067938 | HIV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
| TVIS20068475 | HPV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SMO |
|---|---|
| DrugBank ID | DB08828 |
| Drug Name | Vismodegib |
| Target ID | BE0004659 |
| UniProt ID | Q99835 |
| Regulation Type | antagonist |
| PubMed IDs | 23662017; 24350028 |
| Citations | Sandhiya S, Melvin G, Kumar SS, Dkhar SA: The dawn of hedgehog inhibitors: Vismodegib. J Pharmacol Pharmacother. 2013 Jan;4(1):4-7. doi: 10.4103/0976-500X.107628.@@Aditya S, Rattan A: Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma. Indian Dermatol Online J. 2013 Oct;4(4):365-8. doi: 10.4103/2229-5178.120685. |
| Groups | Approved; Investigational |
| Direct Classification | Benzanilides |
| SMILES | CS(=O)(=O)C1=CC(Cl)=C(C=C1)C(=O)NC1=CC=C(Cl)C(=C1)C1=CC=CC=N1 |
| Pathways | |
| PharmGKB | PA166048558 |
| ChEMBL | CHEMBL473417 |
