| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30067938 | HIV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
| TVIS20068475 | HPV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SMO |
|---|---|
| DrugBank ID | DB09143 |
| Drug Name | Sonidegib |
| Target ID | BE0004659 |
| UniProt ID | Q99835 |
| Regulation Type | antagonist |
| PubMed IDs | 26323341 |
| Citations | Burness CB: Sonidegib: First Global Approval. Drugs. 2015 Sep;75(13):1559-66. doi: 10.1007/s40265-015-0458-y. |
| Groups | Approved; Investigational |
| Direct Classification | Biphenyls and derivatives |
| SMILES | [H][C@]1(C)CN(C[C@@]([H])(C)O1)C1=CC=C(NC(=O)C2=CC=CC(=C2C)C2=CC=C(OC(F)(F)F)C=C2)C=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2105737 |
