| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10008450 | HBV | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS10034714 | HBV | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS20027526 | HPV | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS44009999 | HTLV-1 | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS44012786 | HTLV-1 | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS44033742 | HTLV-1 | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
| TVIS44000630 | HTLV-1 | ENSG00000175344.19 | protein_coding | CHRNA7 | No | No | 1139 | P36544 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRNA7 |
|---|---|
| DrugBank ID | DB11726 |
| Drug Name | Encenicline |
| Target ID | BE0002341 |
| UniProt ID | P36544 |
| Regulation Type | partial agonist |
| PubMed IDs | 25438724 |
| Citations | Barbier AJ, Hilhorst M, Van Vliet A, Snyder P, Palfreyman MG, Gawryl M, Dgetluck N, Massaro M, Tiessen R, Timmerman W, Hilt DC: Pharmacodynamics, pharmacokinetics, safety, and tolerability of encenicline, a selective alpha7 nicotinic receptor partial agonist, in single ascending-dose and bioavailability studies. Clin Ther. 2015 Feb 1;37(2):311-24. doi: 10.1016/j.clinthera.2014.09.013. Epub 2014 Oct 14. |
| Groups | Investigational |
| Direct Classification | 1-benzothiophenes |
| SMILES | ClC1=C2SC(=CC2=CC=C1)C(=O)N[C@H]1CN2CCC1CC2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2151572 |
