| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013130 | HBV | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
| TVIS44026182 | HTLV-1 | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
| TVIS44026183 | HTLV-1 | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TLR4 |
|---|---|
| DrugBank ID | DB06447 |
| Drug Name | E5531 |
| Target ID | BE0002442 |
| UniProt ID | O00206 |
| Regulation Type | |
| PubMed IDs | 12604686; 15993911 |
| Citations | Mullarkey M, Rose JR, Bristol J, Kawata T, Kimura A, Kobayashi S, Przetak M, Chow J, Gusovsky F, Christ WJ, Rossignol DP: Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist. J Pharmacol Exp Ther. 2003 Mar;304(3):1093-102.@@Becker S, Mundandhara S, Devlin RB, Madden M: Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies. Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):269-75. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | [H]N([C@H]1[C@@H](OP(O)(O)=O)O[C@H](CO[C@@H]2O[C@H](COC)[C@@H](OP(O)(O)=O)[C@H](OCC[C@@H](CCCCCCC)OC(=O)CCCC=C/CCCCCC)[C@H]2N([H])C(=O)CC(=O)CCCCCCCCCCC)[C@@H](O)[C@@H]1OCC[C@H](O)CCCCCCC)C(=O)CC(=O)CCCCCCCCCCC |
| Pathways | |
| PharmGKB | |
| ChEMBL |
