| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10013130 | HBV | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
| TVIS44026182 | HTLV-1 | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
| TVIS44026183 | HTLV-1 | ENSG00000136869.16 | protein_coding | TLR4 | No | No | 7099 | O00206 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TLR4 |
|---|---|
| DrugBank ID | DB11193 |
| Drug Name | Papain |
| Target ID | BE0002442 |
| UniProt ID | O00206 |
| Regulation Type | activator |
| PubMed IDs | 25705851 |
| Citations | Stremnitzer C, Manzano-Szalai K, Willensdorfer A, Starkl P, Pieper M, Konig P, Mildner M, Tschachler E, Reichart U, Jensen-Jarolim E: Papain Degrades Tight Junction Proteins of Human Keratinocytes In Vitro and Sensitizes C57BL/6 Mice via the Skin Independent of its Enzymatic Activity or TLR4 Activation. J Invest Dermatol. 2015 Jul;135(7):1790-1800. doi: 10.1038/jid.2015.58. Epub 2015 Feb 23. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
