| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037138 | HBV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS20042252 | HPV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44012590 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44019094 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44025068 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN10A |
|---|---|
| DrugBank ID | DB01002 |
| Drug Name | Levobupivacaine |
| Target ID | BE0000177 |
| UniProt ID | Q9Y5Y9 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 16418020; 10969308; 11094008 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Ueta K, Sugimoto M, Suzuki T, Uchida I, Mashimo T: In vitro antagonism of recombinant ligand-gated ion-channel receptors by stereospecific enantiomers of bupivacaine. Reg Anesth Pain Med. 2006 Jan-Feb;31(1):19-25.@@Vladimirov M, Nau C, Mok WM, Strichartz G: Potency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies. Anesthesiology. 2000 Sep;93(3):744-55.@@Brau ME, Branitzki P, Olschewski A, Vogel W, Hempelmann G: Block of neuronal tetrodotoxin-resistant Na+ currents by stereoisomers of piperidine local anesthetics. Anesth Analg. 2000 Dec;91(6):1499-505. |
| Groups | Approved; Investigational |
| Direct Classification | Piperidinecarboxamides |
| SMILES | CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C |
| Pathways | Levobupivacaine Action Pathway |
| PharmGKB | PA164754741 |
| ChEMBL | CHEMBL1201193 |
