| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037138 | HBV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS20042252 | HPV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44012590 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44019094 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44025068 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN10A |
|---|---|
| DrugBank ID | DB06218 |
| Drug Name | Lacosamide |
| Target ID | BE0000177 |
| UniProt ID | Q9Y5Y9 |
| Regulation Type | blocker |
| PubMed IDs | 10592235; 18378801 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Sheets PL, Heers C, Stoehr T, Cummins TR: Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine. J Pharmacol Exp Ther. 2008 Jul;326(1):89-99. doi: 10.1124/jpet.107.133413. Epub 2008 Mar 31. |
| Groups | Approved |
| Direct Classification | N-acyl-alpha amino acids and derivatives |
| SMILES | COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA166160048 |
| ChEMBL | CHEMBL58323 |
