Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10037138HBVENSG00000185313.9protein_codingSCN10ANoNo6336Q9Y5Y9
TVIS20042252HPVENSG00000185313.9protein_codingSCN10ANoNo6336Q9Y5Y9
TVIS44012590HTLV-1ENSG00000185313.9protein_codingSCN10ANoNo6336Q9Y5Y9
TVIS44019094HTLV-1ENSG00000185313.9protein_codingSCN10ANoNo6336Q9Y5Y9
TVIS44025068HTLV-1ENSG00000185313.9protein_codingSCN10ANoNo6336Q9Y5Y9
TCGA Plot Options
Drug Information
GeneSCN10A
DrugBank IDDB00721
Drug NameProcaine
Target IDBE0000177
UniProt IDQ9Y5Y9
Regulation Typeinhibitor
PubMed IDs9768788; 8581044; 2167458
CitationsBrau ME, Vogel W, Hempelmann G: Fundamental properties of local anesthetics: half-maximal blocking concentrations for tonic block of Na+ and K+ channels in peripheral nerve. Anesth Analg. 1998 Oct;87(4):885-9.@@Katalymov LL: [The effect of inhibitors of sodium permeability (novocaine and tetrodotoxin) on the trace depolarization of myelinated nerve fibers]. Fiziol Zh Im I M Sechenova. 1995 Sep;81(9):127-33.@@Creveling CR, Bell ME, Burke TR Jr, Chang E, Lewandowski-Lovenberg GA, Kim CH, Rice KC, Daly JW: Procaine isothiocyanate: an irreversible inhibitor of the specific binding of [3H]batrachotoxinin-A benzoate to sodium channels. Neurochem Res. 1990 Apr;15(4):441-8.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationBenzoic acid esters
SMILESCCN(CC)CCOC(=O)C1=CC=C(N)C=C1
PathwaysProcaine Action Pathway
PharmGKBPA451110
ChEMBLCHEMBL569