| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037138 | HBV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS20042252 | HPV | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44012590 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44019094 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
| TVIS44025068 | HTLV-1 | ENSG00000185313.9 | protein_coding | SCN10A | No | No | 6336 | Q9Y5Y9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN10A |
|---|---|
| DrugBank ID | DB00527 |
| Drug Name | Cinchocaine |
| Target ID | BE0000177 |
| UniProt ID | Q9Y5Y9 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 9742684; 8798723 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Louro SR, Anteneodo C, Wajnberg E: Carboxyl groups at the membrane interface as molecular targets for local anesthetics. Biophys Chem. 1998 Aug 4;74(1):35-43.@@Ryan SE, Demers CN, Chew JP, Baenziger JE: Structural effects of neutral and anionic lipids on the nicotinic acetylcholine receptor. An infrared difference spectroscopy study. J Biol Chem. 1996 Oct 4;271(40):24590-7. |
| Groups | Approved; Vet_approved |
| Direct Classification | Quinolones and derivatives |
| SMILES | CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC |
| Pathways | Dibucaine Action Pathway |
| PharmGKB | PA449286 |
| ChEMBL | CHEMBL1086 |
