| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20001023 | HPV | ENSG00000120903.13 | protein_coding | CHRNA2 | No | No | 1135 | Q15822 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | CHRNA2 |
|---|---|
| DrugBank ID | DB01245 |
| Drug Name | Decamethonium |
| Target ID | BE0000738 |
| UniProt ID | Q15822 |
| Regulation Type | partial agonist |
| PubMed IDs | 17139284; 17016423; 12067008; 7848904; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Lee C, Jones T: Molecular conformation-activity relationship of decamethonium congeners. Br J Anaesth. 2002 May;88(5):692-9.@@Maneckjee R, Minna JD: Opioids induce while nicotine suppresses apoptosis in human lung cancer cells. Cell Growth Differ. 1994 Oct;5(10):1033-40.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Decamethonium compounds |
| SMILES | C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C |
| Pathways | |
| PharmGKB | PA164747980 |
| ChEMBL | CHEMBL1190 |
