| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20001023 | HPV | ENSG00000120903.13 | protein_coding | CHRNA2 | No | No | 1135 | Q15822 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRNA2 |
|---|---|
| DrugBank ID | DB00416 |
| Drug Name | Metocurine iodide |
| Target ID | BE0000738 |
| UniProt ID | Q15822 |
| Regulation Type | antagonist |
| PubMed IDs | 17139284; 17016423; 18633030; 6107062; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Liu M, Dilger JP: Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. doi: 10.1213/ane.0b013e31817b4469.@@Iwatsuki N, Hashimoto Y, Amaha K, Obara S, Iwatsuki K: Inotropic effects of non-depolarizing muscle relaxants in isolated canine heart muscle. Anesth Analg. 1980 Oct;59(10):717-21.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Withdrawn |
| Direct Classification | Diarylethers |
| SMILES | [I-].[I-].[H][C@@]12CC3=CC=C(OC4=C5C(CC[N+](C)(C)[C@]5([H])CC5=CC(OC6=C(OC)C=C(CC[N+]1(C)C)C2=C6)=C(OC)C=C5)=CC(OC)=C4OC)C=C3 |
| Pathways | |
| PharmGKB | PA164749507 |
| ChEMBL | CHEMBL1739 |
