| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006464 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30015075 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30000135 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036570 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036571 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036572 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30017484 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS20020574 | HPV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HIF1A |
|---|---|
| DrugBank ID | DB01275 |
| Drug Name | Hydralazine |
| Target ID | BE0002374 |
| UniProt ID | Q16665 |
| Regulation Type | inducer |
| PubMed IDs | 15192023 |
| Citations | Knowles HJ, Tian YM, Mole DR, Harris AL: Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circ Res. 2004 Jul 23;95(2):162-9. Epub 2004 Jun 10. |
| Groups | Approved |
| Direct Classification | Phthalazines |
| SMILES | NNC1=NN=CC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA449894 |
| ChEMBL | CHEMBL276832 |
