| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006464 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30015075 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30000135 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036570 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036571 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036572 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30017484 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS20020574 | HPV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HIF1A |
|---|---|
| DrugBank ID | DB12255 |
| Drug Name | Vadadustat |
| Target ID | BE0002374 |
| UniProt ID | Q16665 |
| Regulation Type | stabilization |
| PubMed IDs | 31477256 |
| Citations | Sanghani NS, Haase VH: Hypoxia-Inducible Factor Activators in Renal Anemia: Current Clinical Experience. Adv Chronic Kidney Dis. 2019 Jul;26(4):253-266. doi: 10.1053/j.ackd.2019.04.004. |
| Groups | Approved; Investigational |
| Direct Classification | N-acyl-alpha amino acids |
| SMILES | OC(=O)CNC(=O)C1=C(O)C=C(C=N1)C1=CC(Cl)=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3646221 |
