| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006464 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30015075 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30000135 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036570 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036571 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036572 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30017484 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS20020574 | HPV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HIF1A |
|---|---|
| DrugBank ID | DB06082 |
| Drug Name | PX-478 |
| Target ID | BE0002374 |
| UniProt ID | Q16665 |
| Regulation Type | inhibitor |
| PubMed IDs | 20587661 |
| Citations | Schwartz DL, Bankson JA, Lemos R Jr, Lai SY, Thittai AK, He Y, Hostetter G, Demeure MJ, Von Hoff DD, Powis G: Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer. Mol Cancer Ther. 2010 Jul;9(7):2057-67. doi: 10.1158/1535-7163.MCT-09-0768. Epub 2010 Jun 29. |
| Groups | Investigational |
| Direct Classification | Phenylalanine and derivatives |
| SMILES | Cl.Cl.N[C@@H](CC1=CC=C(C=C1)[N+]([O-])(CCCl)CCCl)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL4061538 |
