| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006464 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30015075 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30000135 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036570 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036571 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30036572 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS30017484 | HIV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
| TVIS20020574 | HPV | ENSG00000100644.17 | protein_coding | HIF1A | Yes | No | 3091 | D0VY79 Q16665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HIF1A |
|---|---|
| DrugBank ID | DB02342 |
| Drug Name | 2-Methoxyestradiol |
| Target ID | BE0002374 |
| UniProt ID | Q16665 |
| Regulation Type | |
| PubMed IDs | 17716391; 17498737 |
| Citations | Zhou D, Matchett GA, Jadhav V, Dach N, Zhang JH: The effect of 2-methoxyestradiol, a HIF-1 alpha inhibitor, in global cerebral ischemia in rats. Neurol Res. 2008 Apr;30(3):268-71. Epub 2007 Aug 22.@@Dai Y, Xu M, Wang Y, Pasha Z, Li T, Ashraf M: HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia. J Mol Cell Cardiol. 2007 Jun;42(6):1036-44. Epub 2007 Apr 6. |
| Groups | Investigational |
| Direct Classification | |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C(OC)=C3 |
| Pathways | |
| PharmGKB | PA13496724 |
| ChEMBL | CHEMBL299613 |
