| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44021886 | HTLV-1 | ENSG00000121966.8 | protein_coding | CXCR4 | Yes | No | 7852 | A0A0U3FJG0 A0A0U3GXA9 P61073 |
| TVIS44032449 | HTLV-1 | ENSG00000121966.8 | protein_coding | CXCR4 | Yes | No | 7852 | A0A0U3FJG0 A0A0U3GXA9 P61073 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CXCR4 |
|---|---|
| DrugBank ID | DB05501 |
| Drug Name | Mavorixafor |
| Target ID | BE0000919 |
| UniProt ID | P61073 |
| Regulation Type | antagonist |
| PubMed IDs | 33275726; 15934866 |
| Citations | Castillo JJ, Treon SP: Management of Waldenstrom macroglobulinemia in 2020. Hematology Am Soc Hematol Educ Program. 2020 Dec 4;2020(1):372-379. doi: 10.1182/hematology.2020000121.@@De Clercq E: Emerging anti-HIV drugs. Expert Opin Emerg Drugs. 2005 May;10(2):241-73. |
| Groups | Investigational |
| Direct Classification | Aminoquinolines and derivatives |
| SMILES | NCCCCN(CC1=NC2=CC=CC=C2N1)[C@H]1CCCC2=C1N=CC=C2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL518924 |
