| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44021886 | HTLV-1 | ENSG00000121966.8 | protein_coding | CXCR4 | Yes | No | 7852 | A0A0U3FJG0 A0A0U3GXA9 P61073 |
| TVIS44032449 | HTLV-1 | ENSG00000121966.8 | protein_coding | CXCR4 | Yes | No | 7852 | A0A0U3FJG0 A0A0U3GXA9 P61073 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CXCR4 |
|---|---|
| DrugBank ID | DB12715 |
| Drug Name | MSX-122 |
| Target ID | BE0000919 |
| UniProt ID | P61073 |
| Regulation Type | antagonist |
| PubMed IDs | 22485156 |
| Citations | Liang Z, Zhan W, Zhu A, Yoon Y, Lin S, Sasaki M, Klapproth JM, Yang H, Grossniklaus HE, Xu J, Rojas M, Voll RJ, Goodman MM, Arrendale RF, Liu J, Yun CC, Snyder JP, Liotta DC, Shim H: Development of a unique small molecule modulator of CXCR4. PLoS One. 2012;7(4):e34038. doi: 10.1371/journal.pone.0034038. Epub 2012 Apr 2. |
| Groups | Investigational |
| Direct Classification | Benzylamines |
| SMILES | C(NC1=NC=CC=N1)C1=CC=C(CNC2=NC=CC=N2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3545330 |
