Gene: EFCAB10

100130771
-
EF-hand calcium binding domain 10
protein-coding
7q22.3
Ensembl:ENSG00000185055 Vega:OTTHUMG00000157397 UniprotKB:A6NFE3
NC_000007.14
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.893e-1 (AD)  9.526e-3 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1706923chr7:105580650 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ODF2L0.78
ABCA50.778
LRRC70.774
MTMR70.773
NPY5R0.768
SGIP10.767
MBLAC20.766
ZDBF20.765
TUBGCP50.764
ATR0.764

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
AKR1C3-0.419
MTRNR2L9-0.413
FOXJ1-0.41
MSX1-0.406
MTRNR2L10-0.403
EYA2-0.393
C4orf19-0.392
CSAG1-0.383
RAB13-0.382
MTRNR2L8-0.374

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of EFCAB10 mRNA22230336
C006780bisphenol Abisphenol A results in decreased expression of EFCAB10 mRNA24586524
C006780bisphenol Abisphenol A results in decreased expression of EFCAB10 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of EFCAB10 gene28505145
D003300CopperCopper deficiency results in increased expression of EFCAB10 mRNA26033743
D003471CuprizoneCuprizone results in increased expression of EFCAB10 mRNA26577399
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of EFCAB10 mRNA27392435
D002945CisplatinCisplatin results in increased expression of EFCAB10 mRNA27392435
D019422Dietary SucroseDietary Sucrose results in increased expression of EFCAB10 mRNA26033743
C412815GW 4064GW 4064 results in increased expression of EFCAB10 mRNA26655953
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of EFCAB10 mRNA27392435
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of EFCAB10 mRNA28001369
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate affects the expression of EFCAB10 mRNA21195148
C028577monobutyl phthalatemonobutyl phthalate affects the expression of EFCAB10 mRNA21195148
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of EFCAB10 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of EFCAB10 mRNA"25554681
C006253pirinixic acidpirinixic acid results in increased expression of EFCAB10 mRNA20813756
C005556propionaldehydepropionaldehyde results in increased expression of EFCAB10 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in increased expression of EFCAB10 mRNA24780913
D053260SootSoot results in decreased expression of EFCAB10 mRNA26551751
C009495titanium dioxidetitanium dioxide results in decreased expression of EFCAB10 mRNA23557971
C025643vinclozolinvinclozolin results in decreased expression of EFCAB10 mRNA23555832

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal