Gene: SMIM6

100130933
C17orf110|ELN
small integral membrane protein 6
protein-coding
17q25.1
Ensembl:ENSG00000259120 Vega:OTTHUMG00000179796 UniprotKB:P0DI80
NC_000017.11
PubMed
0   ANCO-SNPs
ND
0   
NA (AD)  3.460e-1 (ND)   (Frontal_Cortex)
9.798e-1 (AD)  5.149e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
BTBD160.878
DMRT20.878
NINJ20.87
SMIM50.868
NIPAL40.855
DNAH170.846
FXYD40.845
TMEM1250.838
TSPAN150.834
GJB10.831

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CUX2-0.507
LTK-0.438
BEAN1-0.42
GPR153-0.418
CHRNA2-0.413
PCDH8-0.412
MGAT5B-0.412
KIAA1522-0.409
NEUROD1-0.398
GRB14-0.397

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of SMIM6 gene27153756
C022921benzo(k)fluoranthenebenzo(k)fluoranthene results in increased expression of SMIM6 mRNA26377693
D016572CyclosporineCyclosporine results in increased expression of SMIM6 mRNA25562108
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of SMIM6 mRNA26865667
D019833GenisteinGenistein affects the expression of SMIM6 mRNA26865667
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SMIM6 mRNA"25554681
D014241TrichloroethyleneTrichloroethylene results in decreased expression of SMIM6 mRNA25549359
D014635Valproic AcidValproic Acid results in decreased expression of SMIM6 mRNA29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal