Gene: KIR2DS2

100132285
183ActI|CD158J|CD158b|KIR-2DS2|NKAT-5|NKAT5|cl-49
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
protein-coding
19q13.4
MIM:604953 UniprotKB:P43631
NC_000019.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D002104CadmiumCadmium results in decreased expression of KIR2DS2 mRNA24376830
D008727MethotrexateMethotrexate results in decreased expression of KIR2DS2 mRNA24449571
D019821SimvastatinSimvastatin results in decreased expression of KIR2DS2 mRNA18192897
D018038Sodium SeleniteSodium Selenite results in increased expression of KIR2DS2 mRNA18175754

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004888transmembrane signaling receptor activity-NAS8627176  
GO ID GO Term Qualifier Evidence PubMed
GO:0006955immune response-NAS8627176  
GO:0007165signal transduction-IEA-  
GO:0045087innate immune response-TAS-  
GO:0050776regulation of immune response-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-NAS8627176  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1280218Adaptive Immune SystemTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-198933Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellTAS
R-HSA-2172127DAP12 interactionsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26564630[Association between polymorphisms of killer cell immunoglobulin-like receptor gene and the risk of essential hypertension: a case-control study]. (2015 Jun)Zhou XZhonghua Liu Xing Bing Xue Za Zhi