Gene: CD24

100133941
CD24A
CD24 molecule
protein-coding
6q21
Ensembl:ENSG00000272398 MIM:600074 Vega:OTTHUMG00000188439 UniprotKB:P25063
NG_041768.1
PubMed
0   ANCO-SNPs
ND|AD
5   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the expression of CD24 mRNA"19414516
C0065512-amino-2-methyl-1-propanol2-amino-2-methyl-1-propanol results in decreased expression of CD24 mRNA25088246
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD24 mRNA"23196670
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CD24 mRNA"20959002
C5830744,4'-hexafluorisopropylidene diphenol"4,4'-hexafluorisopropylidene diphenol results in increased expression of CD24 mRNA"25912373
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of CD24 mRNA26690555
D020106AcrylamideAcrylamide results in decreased expression of CD24 mRNA28959563
C016601afimoxifeneafimoxifene results in increased expression of CD24 mRNA16514628
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CD24 mRNA23630614
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in decreased expression of CD24 mRNA28522335
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CD24 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of CD24 mRNA24449571
C015001arsenitearsenite results in decreased methylation of CD24 promoter23974009
D001205Ascorbic Acid[Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA17639512
D001414BacitracinBacitracin results in increased expression of CD24 mRNA18289764
C487081belinostatbelinostat results in increased expression of CD24 mRNA26272509
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD24 mRNA18164116
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of CD24 mRNA20660070
D004958EstradiolEstradiol results in decreased expression of CD24 mRNA16514628|2118537
C006780bisphenol Abisphenol A results in increased expression of CD24 mRNA22576693
C006780bisphenol Abisphenol A results in increased methylation of CD24 gene28505145
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of CD24 mRNA15336504
C018475butyraldehydebutyraldehyde results in decreased expression of CD24 mRNA26079696
D002220CarbamazepineCarbamazepine affects the expression of CD24 mRNA25979313
C054133casticincasticin results in increased expression of CD24 mRNA27862857
C100187chloropicrinchloropicrin results in decreased expression of CD24 mRNA26352163
D002857ChromiumChromium results in decreased expression of CD24 mRNA21437242
C018021cobaltous chloridecobaltous chloride results in decreased expression of CD24 mRNA19376846
C018021cobaltous chloridecobaltous chloride results in increased expression of CD24 protein24842335
C018021cobaltous chloridetriptolide inhibits the reaction [cobaltous chloride results in increased expression of CD24 protein]24842335
C018021cobaltous chloridecobaltous chloride results in decreased expression of CD24 mRNA24386269
D003300CopperCopper deficiency results in increased expression of CD24 mRNA26033743
D019327Copper SulfateCopper Sulfate results in decreased expression of CD24 mRNA19549813
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in decreased expression of CD24 mRNA19167446
D003471CuprizoneCuprizone results in decreased expression of CD24 mRNA27523638
C014347decitabinedecitabine inhibits the reaction [Smoke results in decreased expression of CD24 mRNA]21095227
C014347decitabinedecitabine results in increased expression of CD24 mRNA19194470
D003907DexamethasoneDexamethasone results in increased expression of CD24 mRNA14618091|2003205
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in increased expression of CD24 mRNA]20032058
D002945CisplatinCisplatin results in increased expression of CD24 mRNA18289764
D019422Dietary SucroseDietary Sucrose results in increased expression of CD24 mRNA26033743
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD24 mRNA18164116
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of CD24 mRNA19638242
D002117CalcitriolCalcitriol results in increased expression of CD24 mRNA21592394|2648566
D002117Calcitriol[Testosterone co-treated with Calcitriol] results in increased expression of CD24 mRNA21592394
D004237DiuronDiuron results in decreased expression of CD24 mRNA21551480
C118739entinostatentinostat results in increased expression of CD24 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CD24 mRNA16079270
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CD24 mRNA12655037|1557682
D005472FluorouracilFluorouracil results in increased expression of CD24 mRNA16510598
C070081fulvestrantfulvestrant results in increased expression of CD24 mRNA16514628
C039281furanfuran results in decreased methylation of CD24 gene27387713
C039281furanfuran results in increased expression of CD24 mRNA26194646|2738771
C010176halofuginonehalofuginone results in increased expression of CD24 mRNA17180598
D006581HexachlorobenzeneHexachlorobenzene affects the expression of CD24 mRNA15159207
C016517indole-3-carbinolindole-3-carbinol affects the expression of CD24 mRNA21396975
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of CD24 mRNA24796395
D007649KetamineKetamine results in decreased expression of CD24 mRNA20080153
C490728lapatinib[lapatinib results in decreased susceptibility to lapatinib] which results in decreased expression of CD24 protein26643609
D008727MethotrexateMethotrexate results in increased expression of CD24 mRNA24449571
D008731MethoxychlorMethoxychlor results in increased methylation of CD24 gene23303685
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CD24 mRNA23179753|2627250
C004925methylmercuric chloride"[NOG protein co-treated with methylmercuric chloride co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of CD24 mRNA16026605
D015735MifepristoneMifepristone results in decreased expression of CD24 mRNA25972201
C000621033napabucasinnapabucasin results in decreased expression of CD24 mRNA25605917
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of CD24 mRNA25380136
D009532NickelNickel results in increased expression of CD24 mRNA25583101
C014707nitrosobenzylmethylaminenitrosobenzylmethylamine results in increased expression of CD24 mRNA17616710
C558013NSC 689534NSC 689534 results in increased expression of CD24 mRNA20971185
C025589ochratoxin Aochratoxin A results in decreased expression of CD24 mRNA19287073
D009966OrphenadrineOrphenadrine affects the expression of CD24 mRNA23665939
C030110oxaliplatinoxaliplatin results in increased expression of CD24 mRNA16510598
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CD24 mRNA25729387
C030110oxaliplatinoxaliplatin results in decreased expression of CD24 mRNA25729387
D010126OzoneOzone results in increased expression of CD24 mRNA16330353
D017239PaclitaxelPaclitaxel results in decreased expression of CD24 mRNA19682730
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of CD24 mRNA26272509
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of CD24 mRNA26705709
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of CD24 mRNA18692542
D010634PhenobarbitalPhenobarbital affects the expression of CD24 mRNA19159669
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CD24 mRNA22714537
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of CD24 mRNA20660070
D011374ProgesteroneProgesterone results in decreased expression of CD24 mRNA21795739
D011441PropylthiouracilPropylthiouracil results in increased expression of CD24 mRNA24780913
D011794Quercetin[Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA17639512
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of CD24 mRNA16514628
C059514resveratrol[Coumestrol co-treated with resveratrol] results in decreased expression of CD24 mRNA19167446
D012524SarinSarin results in decreased expression of CD24 mRNA19522546
D012524SarinSarin results in increased expression of CD24 mRNA19522546
D012834SilverSilver results in increased expression of CD24 mRNA26014281
D019821SimvastatinSimvastatin results in increased expression of CD24 mRNA18192897
D012906Smokedecitabine inhibits the reaction [Smoke results in decreased expression of CD24 mRNA]21095227
C017947sodium arsenitesodium arsenite affects the methylation of CD24 gene28589171
C017947sodium arsenitesodium arsenite results in decreased expression of CD24 mRNA12634122|2406803
C017947sodium arsenitesodium arsenite results in increased expression of CD24 mRNA23137061
D012999SomanSoman results in increased expression of CD24 mRNA19281266
D013739Testosterone[Testosterone co-treated with Calcitriol] results in increased expression of CD24 mRNA21592394
D013739TestosteroneTestosterone results in increased expression of CD24 mRNA21592394
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in increased expression of CD24 mRNA]20032058
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CD24 mRNA16102516
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CD24 mRNA20959002|2121527
D013853ThioacetamideThioacetamide results in increased expression of CD24 mRNA23411599
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CD24 mRNA22363418|2806579
D019772TopotecanCD24 protein affects the susceptibility to Topotecan16217747
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CD24 mRNA25729387
D014192TrapidilTrapidil affects the reaction [PTH protein affects the expression of CD24 mRNA]18635661
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of CD24 mRNA24935251|2627250
C001899triptolidetriptolide inhibits the reaction [cobaltous chloride results in increased expression of CD24 protein]24842335
D014415TunicamycinTunicamycin results in decreased expression of CD24 mRNA22378314
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CD24 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CD24 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CD24 mRNA26272509
D014638VanadatesVanadates results in increased expression of CD24 mRNA22714537
D014640VancomycinVancomycin results in increased expression of CD24 mRNA18289764
D015032ZincZinc deficiency results in increased expression of CD24 mRNA11717422

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI8753773  9129046  15633604  22731636  
GO:0019901protein kinase binding-IPI8753773  
GO:0030296protein tyrosine kinase activator activity-IDA11313396  
GO ID GO Term Qualifier Evidence PubMed
GO:0001666response to hypoxia-IEP15174142  
GO:0001775cell activation-IDA8223854  
GO:0001959regulation of cytokine-mediated signaling pathway-ISS16390867  
GO:0002237response to molecule of bacterial origin-ISS15493995  
GO:0002768immune response-regulating cell surface receptor signaling pathway-IC11313396  
GO:0007204positive regulation of cytosolic calcium ion concentration-IDA2153173  8223854  
GO:0016055Wnt signaling pathway-NAS16532032  
GO:0016477cell migration-ISS16390867  
GO:0030856regulation of epithelial cell differentiation-NAS16930538  
GO:0031295T cell costimulation-IDA11272271  
GO:0032597B cell receptor transport into membrane raft-IDA11313396  
GO:0032600chemokine receptor transport out of membrane raft-ISS-  
GO:0032913negative regulation of transforming growth factor beta3 production-IMP16930538  
GO:0042104positive regulation of activated T cell proliferation-IDA11272271  
GO:0042325regulation of phosphorylation-IDA11313396  
GO:0042632cholesterol homeostasis-ISS16390867  
GO:0043406positive regulation of MAP kinase activity-IDA12496407  
GO:0043408regulation of MAPK cascade-IDA11313396  
GO:0043627response to estrogen-IEP10037815  
GO:0045730respiratory burst-IDA8223854  
GO:0061098positive regulation of protein tyrosine kinase activity-IEA-  
GO:0072112glomerular visceral epithelial cell differentiation-IMP19092120  
GO:0072139glomerular parietal epithelial cell differentiation-IMP19092120  
GO:0097193intrinsic apoptotic signaling pathway-NAS11313396  
GO:0098609cell-cell adhesion-NAS15633604  
GO:2000768positive regulation of nephron tubule epithelial cell differentiation-IMP16885410  
GO ID GO Term Qualifier Evidence PubMed
GO:0005622intracellular-IEA-  
GO:0009986cell surface-IDA16532032  
GO:0016020membrane-IDA10037815  
GO:0031362anchored component of external side of plasma membrane-IBA21873635  
GO:0045121membrane raft-IDA11313396  
KEGG ID KEGG Term
hsa04640Hematopoietic cell lineage
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyIEA
R-HSA-373760L1CAM interactionsIEA
R-HSA-422475Axon guidanceIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
21073537Cancer stem cell immunophenotypes in oral squamous cell carcinoma. (2011 Feb)Oliveira LRJ Oral Pathol Med
18570728[Expression and significance of CD44(+)ESA(+)CD24(-/low), stem cell markers for breast cancer, in non-small-cell lung carcinoma]. (2008 Jun)Lu ZQAi Zheng
21487404Disulfiram modulated ROS-MAPK and NFkappaB pathways and targeted breast cancer cells with cancer stem cell-like properties. (2011 May 10)Yip NCBr J Cancer
26226399Regulatory B Cell Function Is Suppressed by Smoking and Obesity in H. pylori-Infected Subjects and Is Correlated with Elevated Risk of Gastric Cancer. (2015)Li GPLoS One
23974104High-throughput screen identifies disulfiram as a potential therapeutic for triple-negative breast cancer cells: interaction with IQ motif-containing factors. (2013 Sep 15)Robinson TJCell Cycle