Gene: BCL2L11

10018
BAM|BIM|BOD
BCL2 like 11
protein-coding
2q13
Ensembl:ENSG00000153094 MIM:603827 Vega:OTTHUMG00000131256 UniprotKB:O43521
NG_029006.1
PubMed
ND
2   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.853e-1 (AD)  8.152e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SP10.789
AFF10.751
ELF10.75
MTUS10.746
IQGAP10.741
ATL30.74
TCF120.739
ROCK10.734
CREB3L20.731
KDM5A0.729

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZSCAN1-0.375
CRH-0.36
OR4F5-0.35
OR4F29-0.341
CRYBA2-0.339
VGF-0.321
SPEF1-0.317
BHLHA9-0.313
DLK2-0.308
ABCC12-0.304

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C50489712-(3-adamantan-1-ylureido)dodecanoic acid12-(3-adamantan-1-ylureido)dodecanoic acid results in decreased expression of BCL2L11 mRNA19435785
C5395511,2,4,5-benzenetetraamine"1,2,4,5-benzenetetraamine results in increased cleavage of BCL2L11 protein"22276220
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with GDC-0973] results in decreased phosphorylation of BCL2L11 protein alternative form"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased expression of BCL2L11 protein]"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased expression of BCL2L11 protein alternative form]"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BCL2L11 mRNA"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BCL2L11 protein"23318440
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BCL2L11 protein alternative form"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"BCL2L11 results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"GDC-0973 promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BCL2L11 protein alternative form]"22084396
C5321622-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine"[sorafenib co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of BCL2L11 protein"23036488
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether affects the expression of BCL2L11 mRNA"27589474
C4408502,4,3',5'-tetramethoxystilbene"2,4,3',5'-tetramethoxystilbene results in increased expression of BCL2L11 protein"20490654
C4408502,4,3',5'-tetramethoxystilbene"BCL2L11 protein results in increased susceptibility to 2,4,3',5'-tetramethoxystilbene"20490654
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of BCL2L11 mRNA]"21851831
C5614542,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide"[trametinib co-treated with 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide] results in increased expression of BCL2L11 protein"22733540
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Doxorubicin] results in decreased phosphorylation of BCL2L11 protein20856197
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of BCL2L11 protein alternative form21179458
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-oneresveratrol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of BCL2L11 protein alternative form]21179458
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]]25471227
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of BCL2L11 mRNA"23196670
C4340033-(4-methylphenylsulfonyl)-2-propenenitrile3-(4-methylphenylsulfonyl)-2-propenenitrile results in increased expression of BCL2L11 protein20067466
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C0275764-hydroxy-2-nonenal4-hydroxy-2-nonenal results in increased expression of BCL2L11 mRNA19191707
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BCL2L11 mRNA23820845
C0789564-methylthioamphetamine4-methylthioamphetamine results in increased expression of BCL2L11 protein23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA"23820845
C0789564-methylthioamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein"23820845
C0415944-nonylphenol4-nonylphenol results in increased expression of BCL2L11 protein26804764
C0126064-vinyl-1-cyclohexene dioxide4-vinyl-1-cyclohexene dioxide affects the expression of BCL2L11 mRNA20829426
C0342145-iodotubercidin5-iodotubercidin inhibits the reaction [acadesine results in increased expression of BCL2L11 mRNA]20664053
C5805985-OH-BDE-475-OH-BDE-47 results in decreased expression of BCL2L11 mRNA27589474
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C0030017-ketocholesterol7-ketocholesterol affects the localization of BCL2L11 protein15955068
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 protein"14996839
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"BCL2L11 protein results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP"14996839
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 mRNA"14996839
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"8-((4-chlorophenyl)thio)cyclic-3',5'-AMP results in increased expression of BCL2L11 protein"14996839
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"BCL2L11 protein results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP"14996839
C0428349,10-anthraquinone"9,10-anthraquinone analog results in increased expression of BCL2L11 protein"26915975
C501332ABT-737ABT-737 inhibits the reaction [BCL2L11 protein binds to BCL2 protein]17097560|1720071
C501332ABT-737[ABT-737 inhibits the reaction [BCL2L11 protein binds to BCL2 protein]] promotes the reaction [BCL2L11 protein results in increased activity of BAX protein]17200714
C501332ABT-737[BCL2L11 protein binds to BCL2 protein] which affects the susceptibility to ABT-73717200714
C501332ABT-737[MCL1 protein results in decreased activity of BCL2L11 protein] which results in decreased susceptibility to ABT-73723341456
C501332ABT-737BCL2L11 protein results in increased susceptibility to ABT-73720038611
C011651acadesine5-iodotubercidin inhibits the reaction [acadesine results in increased expression of BCL2L11 mRNA]20664053
C011651acadesineacadesine results in increased expression of BCL2L11 mRNA20664053
C011651acadesineacadesine results in increased expression of BCL2L11 protein20664053
D000082AcetaminophenAcetaminophen results in decreased expression of BCL2L11 mRNA26690555
D000082AcetaminophenAcetaminophen results in increased expression of BCL2L11 mRNA21420995|2570463
D000082AcetaminophenAcetaminophen affects the expression of BCL2L11 mRNA17562736
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of BCL2L11 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of BCL2L11 mRNA]17585979
D000111AcetylcysteineAcetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein]15173094
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of BCL2L11 mRNA19770486
D000393Air PollutantsAir Pollutants analog results in decreased expression of BCL2L11 mRNA21757418
C103303alitretinoinalitretinoin results in increased expression of BCL2L11 protein16340750
C103303alitretinoinseocalcitol inhibits the reaction [alitretinoin results in increased expression of BCL2L11 protein]16340750
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of BCL2L11 mRNA21298039
D000638AmiodaroneAmiodarone results in increased expression of BCL2L11 mRNA19774075
D000643Ammonium ChlorideAmmonium Chloride affects the expression of BCL2L11 mRNA16483693
D003913DextroamphetamineDextroamphetamine results in increased expression of BCL2L11 mRNA23820845
D003913DextroamphetamineDextroamphetamine results in increased expression of BCL2L11 protein23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA"23820845
D003913Dextroamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein"23820845
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of BCL2L11 mRNA24449571
C006632arsenic trioxide[arsenic trioxide co-treated with Curcumin] results in increased expression of BCL2L11 protein27430728
C006632arsenic trioxidearsenic trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]24956101
C006632arsenic trioxidearsenic trioxide promotes the reaction [matrine results in increased expression of BCL2L11 protein]23700110
C006632arsenic trioxidearsenic trioxide results in increased expression of BCL2L11 mRNA17530438
C006632arsenic trioxidearsenic trioxide results in increased expression of BCL2L11 protein17203211|2165518
C006632arsenic trioxide[arsenic trioxide results in increased expression of BCL2L11 protein] which results in decreased phosphorylation of AKT1 protein21655183
C006632arsenic trioxideBCL2L11 mutant form inhibits the reaction [arsenic trioxide results in increased cleavage of CASP3 protein]21655183
C006632arsenic trioxideBCL2L11 mutant form inhibits the reaction [arsenic trioxide results in increased cleavage of CASP9 protein]21655183
C006632arsenic trioxidematrine promotes the reaction [arsenic trioxide results in increased expression of BCL2L11 protein]23700110
C006632arsenic trioxideMMP9 protein inhibits the reaction [arsenic trioxide inhibits the reaction [BCL2L11 protein binds to MCL1 protein]]24956101
C006632arsenic trioxideMMP9 protein inhibits the reaction [arsenic trioxide results in increased expression of BCL2L11 protein]24956101
D001194AsbestosAsbestos results in decreased expression of BCL2L1127042963
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in decreased expression of BCL2L11 mRNA"18687144
D001241AspirinAspirin results in increased expression of BCL2L11 mRNA19936928
C406592azaspiracidazaspiracid results in decreased expression of BCL2L11 mRNA28939011
C517975AZD 6244AZD 6244 results in increased expression of BCL2L11 protein22729845
C487081belinostatbelinostat results in increased expression of BCL2L11 protein18223231
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of BCL2L11 protein21392559
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BCL2L11 mRNA26238291
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BCL2L11 mRNA15735009
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BCL2L11 mRNA20713471
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of BCL2L11 mRNA19770486|2171566
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased methylation of BCL2L11 gene28476633
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehyde[benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein]] which results in increased susceptibility to Cisplatin21561860
D001599Berberine[Berberine co-treated with Niacinamide] results in increased expression of BCL2L11 mRNA26712469
D001599BerberineBerberine results in increased expression of BCL2L11 mRNA26712469
D004958EstradiolEstradiol affects the expression of BCL2L11 mRNA21826169
D004958EstradiolEstradiol results in increased expression of BCL2L11 mRNA23373633
C006780bisphenol Abisphenol A affects the expression of BCL2L11 mRNA21826169
C006780bisphenol Abisphenol A results in decreased expression of BCL2L11 mRNA22576693
C006780bisphenol Abisphenol A results in increased methylation of BCL2L11 gene22576693
C006780bisphenol A[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L11 mRNA28628672
C006780bisphenol Abisphenol A results in increased expression of BCL2L11 protein24909818
C006780bisphenol Abisphenol A results in increased methylation of BCL2L11 promoter27312807
C006780bisphenol Abisphenol A affects the expression of BCL2L11 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of BCL2L11 gene28505145
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of BCL2L11 mRNA22434021
D000069286BortezomibAcetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein]15173094
D000069286BortezomibBCL2L11 results in increased susceptibility to Bortezomib18566236
D000069286Bortezomib[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein15173094
D000069286BortezomibBortezomib results in increased activity of BCL2L11 protein16446371
D000069286BortezomibBortezomib results in increased expression of BCL2L11 protein16024631|1732615
C546611brevetoxin 2brevetoxin 2 results in increased expression of BCL2L11 mRNA20498034
D0151248-Bromo Cyclic Adenosine Monophosphate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BCL2L11 protein16709600
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BCL2L1121787858
D019256Cadmium ChlorideCadmium Chloride results in increased expression of BCL2L11 protein28457857
D002220CarbamazepineCarbamazepine affects the expression of BCL2L11 mRNA24752500
D012721CarbarylCarbaryl results in decreased expression of BCL2L11 mRNA27829164
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BCL2L11 mRNA17482686
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of BCL2L11 protein17482686
D002251Carbon TetrachloridePLG protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2L11 protein]17482686
C469298CEP-11004CEP-11004 inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein]16166651
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of BCL2L11 mRNA25270620
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of BCL2L11 mRNA26272509
C074702chromium hexavalent ionchromium hexavalent ion results in increased expression of BCL2L11 mRNA17382205
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of BCL2L11 mRNA28472532
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of BCL2L11 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of BCL2L11 mRNA]17585979
C018021cobaltous chloridecobaltous chloride results in increased expression of BCL2L11 mRNA24386269
D003042CocaineCocaine results in increased expression of BCL2L11 mRNA16076954
D003300Copper[Copper deficiency co-treated with tetrathiomolybdate] results in increased cleavage of BCL2L11 protein22276220
D003300Copper[Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of BCL2L11 protein22276220
C551994crizotinibBCL2L11 protein affects the reaction [crizotinib results in increased cleavage of CASP3 protein]22729845
C551994crizotinibBCL2L11 protein affects the susceptibility to crizotinib22729845
C551994crizotinibcrizotinib results in increased expression of BCL2L11 protein22729845
C551994crizotinibMET gene mutant form promotes the reaction [crizotinib results in increased expression of BCL2L11 protein]22729845
C551994crizotinibcrizotinib results in increased expression of BCL2L1121716144
D003471CuprizoneCuprizone results in increased expression of BCL2L11 mRNA25704630
D003474Curcumin[arsenic trioxide co-treated with Curcumin] results in increased expression of BCL2L11 protein27430728
D003474CurcuminCurcumin results in increased expression of BCL2L11 mRNA17332930
C057862cyanoginosin LRcyanoginosin LR results in increased expression of BCL2L11 mRNA17654400
D003609DactinomycinDactinomycin inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 mRNA]16166651
C531198dactolisibdactolisib affects the expression of BCL2L11 protein25640480
C515055darinaparsinBCL2L11 protein affects the susceptibility to darinaparsin19417148
C515055darinaparsindarinaparsin results in increased expression of BCL2L11 mRNA19417148
C014347decitabinedecitabine results in decreased methylation of BCL2L11 promoter19403302
C014347decitabinedecitabine results in increased expression of BCL2L11 mRNA19403302
C014347decitabinedecitabine results in increased expression of BCL2L11 protein19403302
D003703DemecolcineDemecolcine results in increased expression of BCL2L11 mRNA23649840
D003907DexamethasoneBCL2L11 protein results in increased susceptibility to Dexamethasone14996839
D003907DexamethasoneDexamethasone results in increased expression of BCL2L11 mRNA12782123
D003907DexamethasoneDexamethasone results in increased phosphorylation of BCL2L11 protein20067466
D003907DexamethasoneGSTM1 protein inhibits the reaction [Dexamethasone results in increased phosphorylation of BCL2L11 protein]20067466
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L11 mRNA28628672
D003907DexamethasoneNR3C1 protein affects the reaction [Dexamethasone results in increased expression of BCL2L11 protein]18515658
D003907DexamethasoneBCL2L11 protein results in increased susceptibility to Dexamethasone14996839
D003907DexamethasoneDexamethasone results in increased expression of BCL2L11 mRNA alternative form17953376
D003907DexamethasoneDexamethasone results in increased expression of BCL2L11 protein14996839
C041517dibenzo(a,l)pyrene"dibenzo(a,l)pyrene results in increased methylation of BCL2L11 gene"28476633
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of BCL2L11 mRNA17361019|2126653
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of BCL2L11 mRNA27392435
D002945Cisplatin[Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of BCL2L11 protein21092744
D002945CisplatinCisplatin results in increased expression of BCL2L11 mRNA21092744|2739243
D002945CisplatinSirolimus promotes the reaction [Cisplatin results in increased expression of BCL2L11 mRNA]21092744
D002945Cisplatin[benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein]] which results in increased susceptibility to Cisplatin21561860
D002945CisplatinCisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein21561860
D002945Cisplatin[Cisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein] which results in decreased susceptibility to Cisplatin21561860
D002945CisplatinMAPK1 mutant form inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein]21561860
D002945CisplatinMAPK3 mutant form inhibits the reaction [Cisplatin results in increased phosphorylation of and results in increased degradation of BCL2L11 protein]21561860
D003633Dichlorodiphenyl DichloroethyleneDichlorodiphenyl Dichloroethylene affects the expression of BCL2L11 mRNA24576310
D004008DiclofenacDiclofenac affects the expression of BCL2L11 mRNA24752500
C000944dicrotophosdicrotophos results in increased expression of BCL2L11 mRNA28302478
D004026DieldrinDieldrin affects the expression of BCL2L11 mRNA22546817
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in increased expression of BCL2L11 mRNA22610992
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of BCL2L11 mRNA24535843
D002117CalcitriolCalcitriol results in decreased expression of BCL2L11 mRNA12071473
C010715di-n-octyl phthalatedi-n-octyl phthalate results in decreased expression of BCL2L11 protein29128616
C051904dinophysistoxin 1dinophysistoxin 1 results in increased expression of BCL2L11 mRNA28939011
D004178DiquatDiquat results in increased expression of BCL2L11 mRNA26785375|2705728
D004178Diquatprocyanidin B2 inhibits the reaction [Diquat results in increased expression of BCL2L11 mRNA]27057282
C478085D-JNKI-1D-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]22427801
C478085D-JNKI-1D-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]22427801
C521792DMU-212DMU-212 affects the expression of BCL2L11 mRNA26428916
C067311docetaxeldocetaxel results in increased degradation of BCL2L11 protein17317842
C067311docetaxelpyrazolanthrone inhibits the reaction [docetaxel results in increased degradation of BCL2L11 protein]17317842
C067311docetaxelU 0126 inhibits the reaction [docetaxel results in increased degradation of BCL2L11 protein]17317842
D004317Doxorubicin[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Doxorubicin] results in decreased phosphorylation of BCL2L11 protein20856197
D004317DoxorubicinBCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]17339365
D004317DoxorubicinBCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]17339365
D004317DoxorubicinBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D004317DoxorubicinDoxorubicin results in decreased expression of BCL2L11 protein17339365
D004317DoxorubicinDoxorubicin results in increased expression of BCL2L11 protein25339540
D004317Doxorubicin[PI103 co-treated with Doxorubicin] results in decreased phosphorylation of BCL2L11 protein20856197
D004317DoxorubicinDoxorubicin results in increased expression of BCL2L11 protein26318906
C098320efavirenzBCL2L11 protein results in increased susceptibility to efavirenz metabolite21958719
C098320efavirenzefavirenz metabolite results in increased expression of BCL2L11 mRNA21958719
C098320efavirenzefavirenz metabolite results in increased expression of BCL2L11 protein21958719
C098320efavirenzefavirenz results in increased expression of BCL2L11 mRNA21958719
C098320efavirenzefavirenz results in increased expression of BCL2L11 protein21958719
C100264enniatinsenniatins results in decreased expression of BCL2L11 mRNA27163883
C118739entinostatentinostat results in decreased expression of BCL2L11 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
D000431Ethanol[Ethanol co-treated with FOXO3 protein] results in increased expression of BCL2L11 mRNA26470730
D000431EthanolEthanol promotes the reaction [FOXO3 protein binds to BCL2L11 promoter]26470730
D000431EthanolEthanol promotes the reaction [FOXO3 protein modified form binds to BCL2L11 gene]26470730
D000431Ethanol[Ethanol results in increased phosphorylation of FOXO3 protein] promotes the reaction [FOXO3 protein modified form binds to BCL2L11 gene]26470730
D000431EthanolEthanol results in increased expression of BCL2L11 mRNA24095927
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of BCL2L11 mRNA23649840
C000499ferric oxideferric oxide analog results in increased expression of BCL2L11 mRNA24525745
C000499ferric oxideferric oxide analog results in increased expression of BCL2L11 protein25086211
D005485FlutamideCBL protein affects the reaction [Flutamide results in increased expression of BCL2L11 protein]16301331
D005485FlutamideFlutamide results in increased expression of BCL2L11 protein16301331
D005485FlutamideFlutamide results in increased expression of BCL2L11 mRNA24793618
D005485FlutamideFlutamide results in increased expression of BCL2L11 protein20850791
C065180fluvastatin[zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNA16996129
D005492Folic AcidFolic Acid affects the expression of BCL2L11 mRNA16361273
D005557FormaldehydeFormaldehyde results in increased expression of BCL2L11 mRNA23649840
C039281furanfuran results in increased expression of BCL2L11 mRNA20562052|2207923
D005665FurosemideFurosemide affects the expression of BCL2L11 mRNA17497460
D005707Gallic AcidGallic Acid results in decreased expression of BCL2L11 mRNA29205955
C546771gardiquimodgardiquimod results in increased expression of BCL2L11 mRNA28003376
C546771gardiquimodProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of BCL2L11 mRNA]28003376
C574276GDC-0973"[2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine co-treated with GDC-0973] results in decreased phosphorylation of BCL2L11 protein alternative form"22084396
C574276GDC-0973"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased expression of BCL2L11 protein]"22084396
C574276GDC-0973"2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine promotes the reaction [GDC-0973 results in increased expression of BCL2L11 protein alternative form]"22084396
C574276GDC-0973"GDC-0973 promotes the reaction [2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine results in increased expression of BCL2L11 protein alternative form]"22084396
C574276GDC-0973GDC-0973 results in increased expression of BCL2L11 protein22084396
C574276GDC-0973GDC-0973 results in increased expression of BCL2L11 protein alternative form22084396
C574276GDC-0973BCL2L11 results in increased susceptibility to GDC-097322084396
C574276GDC-0973GDC-0973 results in increased expression of BCL2L11 mRNA22084396
C419708gefitinibBCL2L11 protein results in increased susceptibility to gefitinib20237869
C056507gemcitabinegemcitabine results in increased expression of BCL2L11 mRNA17039268
D005947Glucose2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]]25471227
D005947GlucoseGlucose results in increased expression of BCL2L11 protein25471227
D005947Glucoseresveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]25471227
D006072GossypolGossypol results in increased expression of BCL2L11 protein18840529
D017313FenretinideFenretinide results in increased expression of BCL2L11 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide results in increased expression of BCL2L11 mRNA27057282
D006861Hydrogen Peroxideprocyanidin B2 inhibits the reaction [Hydrogen Peroxide results in increased expression of BCL2L11 mRNA]27057282
C559745hyperforin dicyclohexylammoniumhyperforin dicyclohexylammonium results in increased expression of BCL2L11 protein21376709
C056599icariinicariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
C056599icariinicariin affects the expression of BCL2L11 protein25472572
D000068877Imatinib MesylateBCL2L11 protein results in increased susceptibility to Imatinib Mesylate19403302
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L11 mRNA28628672
C572449INK128INK128 results in increased expression of BCL2L11 mRNA26536665
C572449INK128INK128 results in increased expression of BCL2L11 protein26536665
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2L11 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of BCL2L11 mRNA28628672
D007530IsofluraneIsoflurane results in decreased expression of BCL2L11 mRNA16978161
D007545IsoproterenolIsoproterenol results in increased expression of BCL2L11 mRNA24286936
D007545IsoproterenolIsoproterenol results in increased expression of BCL2L11 protein14996839
D007545IsoproterenolIsoproterenol results in increased expression of BCL2L11 mRNA24286936
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of BCL2L11 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound affects the expression of BCL2L11 mRNA26397223
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [panobinostat results in increased expression of BCL2L11 protein]24435446
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [ponatinib results in increased expression of BCL2L11 protein]25053825
C561695(+)-JQ1 compound(+)-JQ1 compound promotes the reaction [quizartinib results in increased expression of BCL2L11 protein]25053825
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BCL2L1126575167
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BCL2L11 mRNA24796395
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BCL2L11 protein24435446|2505382
C561695(+)-JQ1 compoundpanobinostat promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]24435446
C561695(+)-JQ1 compoundPCI 32765 promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]26254443
C561695(+)-JQ1 compoundponatinib promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]25053825
C561695(+)-JQ1 compoundquizartinib promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]25053825
C561695(+)-JQ1 compound(+)-JQ1 compound affects the expression of BCL2L1127406984
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BCL2L11 protein25053825
D007654KetoconazoleKetoconazole results in increased expression of BCL2L11 mRNA25808816
C008261lead acetatelead acetate results in increased expression of BCL2L11 mRNA21829687
D008148LovastatinLovastatin results in increased expression of BCL2L11 protein18766339
D008148Lovastatinpyrazolanthrone inhibits the reaction [Lovastatin results in increased expression of BCL2L11 protein]18766339
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of BCL2L11 mRNA26378955
D058185Magnetite Nanoparticles[Succimer binds to Magnetite Nanoparticles] which results in increased expression of BCL2L11 mRNA21641980
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of BCL2L11 mRNA26378955
D008344ManebManeb results in increased expression of BCL2L11 protein18266926
D008344Maneb[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 protein18266926
C025340manganese chloridemanganese chloride results in increased expression of BCL2L11 protein25732873
C034244matrinearsenic trioxide promotes the reaction [matrine results in increased expression of BCL2L11 protein]23700110
C034244matrinematrine promotes the reaction [arsenic trioxide results in increased expression of BCL2L11 protein]23700110
C034244matrinematrine results in increased expression of BCL2L11 protein23700110
D017258Medroxyprogesterone Acetate[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of BCL2L11 protein16709600
C042720mercuric bromidemercuric bromide results in decreased expression of BCL2L11 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
D008628MercuryMercury results in decreased expression of BCL2L11 mRNA19937285
D008694MethamphetamineMethamphetamine results in increased expression of BCL2L11 protein23820845
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA"23820845
D008694Methamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein"23820845
C005219methyl cellosolvemethyl cellosolve results in increased expression of BCL2L11 mRNA19643169
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of BCL2L11 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of BCL2L11 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BCL2L11 mRNA"23820845
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of BCL2L11 protein"23820845
D008769Methylnitronitrosoguanidine[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein16030430
D008769MethylnitronitrosoguanidineS-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]16030430
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of BCL2L11 mRNA18266926
C008493methylselenic acidBCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]17339365
C008493methylselenic acidBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]17339365
C008493methylselenic acidBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]17339365
C008493methylselenic acidmethylselenic acid results in increased cleavage of BCL2L11 protein18790785
C008493methylselenic acidmethylselenic acid results in increased expression of BCL2L11 mRNA28161410
C008493methylselenic acidmethylselenic acid results in increased expression of BCL2L11 protein17339365
C008493methylselenic acidTamoxifen promotes the reaction [methylselenic acid results in increased cleavage of BCL2L11 protein]18790785
C008542monodansylcadaverinemonodansylcadaverine results in increased expression of BCL2L11 protein16170020
D009020MorphineMorphine results in increased expression of BCL2L11 protein19292871
D009151Mustard GasMustard Gas results in increased expression of BCL2L11 mRNA18955075
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in increased expression of BCL2L11 mRNA"29244179
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"MYC mutant form inhibits the reaction [N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine results in increased expression of BCL2L11 protein]"24444383
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"[N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine co-treated with MYC protein] results in increased expression of BCL2L11 protein"24444383
C469937N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine"N(2)-(2-aminocyclohexyl)-N(6)-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine results in increased expression of BCL2L11 protein"24444383
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of BCL2L11 mRNA"25554681
C017096n-butoxyethanoln-butoxyethanol results in increased expression of BCL2L11 mRNA19812364
D009532NickelNickel affects the expression of BCL2L11 mRNA14575637
D009532Nickeltrichostatin A inhibits the reaction [Nickel affects the expression of BCL2L11 mRNA]14575637
C022838nickel chloridenickel chloride affects the expression of BCL2L11 mRNA22110744
C029938nickel sulfatenickel sulfate results in increased expression of BCL2L11 mRNA17382205
D015376NimustineBCL2L11 mutant form inhibits the reaction [Nimustine results in increased cleavage of CASP9 protein]26418950
D015376NimustineNimustine results in increased expression of BCL2L11 mRNA26418950
D015376NimustineNimustine results in increased expression of BCL2L11 protein26418950
D015376Nimustinepyrazolanthrone inhibits the reaction [Nimustine results in increased expression of BCL2L11 mRNA]26418950
D019319Okadaic AcidOkadaic Acid results in increased expression of BCL2L11 mRNA28939011
C507134ON 01910ON 01910 results in increased expression of BCL2L1121812421
C016340o,p'-DDT"o,p'-DDT analog results in decreased expression of BCL2L11 mRNA"22937105
C016340o,p'-DDT"o,p'-DDT analog results in increased expression of BCL2L11 mRNA"22937105
C016340o,p'-DDT"o,p'-DDT results in increased expression of BCL2L11 mRNA"22937105
D008939MitotaneMitotane results in increased expression of BCL2L11 mRNA23485034
D010100Oxygenicariin inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
D010100OxygenNiacinamide promotes the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
D010100Oxygen[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein25472572
D010100Oxygenresveratrol inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
D010100OxygenSIRT1 mutant form promotes the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
D017239PaclitaxelBCL2L11 protein affects the susceptibility to Paclitaxel17652622
C496932panobinostat(+)-JQ1 compound promotes the reaction [panobinostat results in increased expression of BCL2L11 protein]24435446
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C496932panobinostatpanobinostat promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]24435446
C496932panobinostatpanobinostat results in decreased expression of BCL2L11 mRNA26272509
C496932panobinostatpanobinostat results in increased expression of BCL2L11 protein24435446
D010269Paraquat[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 protein18266926
D010269ParaquatParaquat results in decreased expression of BCL2L11 mRNA18836921
D010269ParaquatParaquat results in increased expression of BCL2L11 protein18266926
D010269ParaquatFOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]23620592
D010269ParaquatParaquat results in increased expression of BCL2L11 mRNA23620592
D010365PatulinPatulin results in increased expression of BCL2L11 mRNA21844328
C551803PCI 32765PCI 32765 promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]26254443
C539933pevonedistatpevonedistat affects the expression of BCL2L11 mRNA24634471
C539933pevonedistatpevonedistat affects the expression of BCL2L11 protein24634471
D010634PhenobarbitalPhenobarbital affects the expression of BCL2L11 mRNA23091169
D010634PhenobarbitalPhenobarbital results in decreased expression of BCL2L11 mRNA19270015
D010634PhenobarbitalPhenobarbital results in increased expression of BCL2L11 mRNA25270620
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of BCL2L11 mRNA26272509
C522973PI103[PI103 co-treated with Doxorubicin] results in decreased phosphorylation of BCL2L11 protein20856197
C006253pirinixic acidpirinixic acid results in increased expression of BCL2L11 mRNA12832660
D059808PolyphenolsPolyphenols results in decreased expression of BCL2L11 mRNA16293270
C545373ponatinib(+)-JQ1 compound promotes the reaction [ponatinib results in increased expression of BCL2L11 protein]25053825
C545373ponatinibponatinib promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]25053825
C545373ponatinibponatinib results in increased expression of BCL2L11 protein25053825
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of BCL2L11 mRNA17382205
C432807pramanicinBCL2L11 protein affects the susceptibility to pramanicin23441183
C432807pramanicinpramanicin analog results in increased expression of BCL2L11 protein23441183
D044945ProanthocyanidinsProanthocyanidins results in decreased expression of BCL2L11 mRNA29205955
C045362prochlorazprochloraz results in increased expression of BCL2L11 mRNA29038839
C479580procyanidin B2procyanidin B2 inhibits the reaction [Diquat results in increased expression of BCL2L11 mRNA]27057282
C479580procyanidin B2procyanidin B2 inhibits the reaction [Hydrogen Peroxide results in increased expression of BCL2L11 mRNA]27057282
D047428Protein Kinase InhibitorsProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of BCL2L11 mRNA]28003376
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [docetaxel results in increased degradation of BCL2L11 protein]17317842
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Lovastatin results in increased expression of BCL2L11 protein]18766339
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [Nimustine results in increased expression of BCL2L11 mRNA]26418950
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [temozolomide results in increased expression of BCL2L11 mRNA]26418950
C432165pyrazolanthronepyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein]16166651
C031280pyrazolepyrazole results in increased expression of BCL2L11 mRNA17945193
C014175pyrazolo(3,4-d)pyrimidine"pyrazolo(3,4-d)pyrimidine analog affects the expression of BCL2L11 mRNA"21152443
D011794QuercetinQuercetin results in decreased expression of BCL2L11 protein20438634
D011794QuercetinQuercetin results in increased expression of BCL2L11 protein25339540
C544967quizartinib(+)-JQ1 compound promotes the reaction [quizartinib results in increased expression of BCL2L11 protein]25053825
C544967quizartinibquizartinib promotes the reaction [(+)-JQ1 compound results in increased expression of BCL2L11 protein]25053825
C544967quizartinibquizartinib results in increased expression of BCL2L11 protein25053825
D020849Raloxifene HydrochlorideRaloxifene Hydrochloride results in increased expression of BCL2L11 mRNA19429434
D017382Reactive Oxygen Species[[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in decreased expression of BCL2L11 protein27634759
D012116Resins, Plant"Resins, Plant results in increased expression of BCL2L11 protein"27268964
C059514resveratrolBCL2L11 protein promotes the reaction [resveratrol results in increased activity of BAK1 protein]22245142
C059514resveratrolBCL2L11 protein results in increased susceptibility to resveratrol22245142
C059514resveratrolFOXO1 protein affects the reaction [resveratrol results in increased expression of BCL2L11 protein alternative form]21179458
C059514resveratrolFOXO3 protein affects the reaction [resveratrol results in increased expression of BCL2L11 protein alternative form]21179458
C059514resveratrolFOXO4 protein affects the reaction [resveratrol results in increased expression of BCL2L11 protein alternative form]21179458
C059514resveratrolresveratrol inhibits the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
C059514resveratrolresveratrol promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of BCL2L11 protein alternative form]21179458
C059514resveratrolresveratrol results in increased expression of BCL2L11 protein17636462|2198039
C059514resveratrolresveratrol results in increased expression of BCL2L11 protein alternative form21179458
C059514resveratrolresveratrol results in increased expression of BCL2L11 protein20026400|2198039
C059514resveratrol2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [resveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]]25471227
C059514resveratrolresveratrol inhibits the reaction [Glucose results in increased expression of BCL2L11 protein]25471227
C512984RO 3306MYC mutant form inhibits the reaction [RO 3306 results in increased expression of BCL2L11 protein]24444383
C512984RO 3306[RO 3306 co-treated with MYC protein] results in increased expression of BCL2L11 protein24444383
C512984RO 3306RO 3306 results in increased expression of BCL2L11 protein24444383
C087123romidepsinAcetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein]15173094
C087123romidepsin[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein15173094
C087123romidepsinromidepsin results in increased expression of BCL2L11 protein15069698|1822323
C065299S-allylcysteineS-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]16030430
C093642SB 203580SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of BCL2L11 protein]16818494
D012643SeleniumBCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]17339365
D012643SeleniumBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]17339365
D012643SeleniumBCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]17339365
D012643SeleniumSelenium results in increased expression of BCL2L11 protein17339365
C002979selenomethylselenocysteineselenomethylselenocysteine metabolite results in increased expression of BCL2L11 mRNA25321483
C078903seocalcitolseocalcitol inhibits the reaction [alitretinoin results in increased expression of BCL2L11 protein]16340750
D017632Asbestos, Serpentine"Asbestos, Serpentine results in decreased expression of BCL2L11 protein"19116364
D017632Asbestos, Serpentine"PRKD1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]"19116364
D017632Asbestos, Serpentine"U 0126 promotes the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]"19116364
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of BCL2L11 mRNA25895662
D012822Silicon DioxideSilicon Dioxide results in decreased expression of BCL2L11 mRNA25351596
D012822Silicon DioxideSilicon Dioxide results in increased expression of BCL2L11 mRNA19073995
D020123Sirolimus[Cisplatin inhibits the reaction [[Sirolimus results in increased phosphorylation of AKT1 protein] which results in increased phosphorylation of FOXO3 protein]] which results in increased expression of BCL2L11 protein21092744
D020123SirolimusSirolimus promotes the reaction [Cisplatin results in increased expression of BCL2L11 mRNA]21092744
D020123SirolimusSirolimus results in increased expression of BCL2L11 protein21092744
D020123SirolimusSirolimus results in decreased expression of BCL2L11 protein18097008
C017947sodium arseniteCEP-11004 inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein]16166651
C017947sodium arseniteDactinomycin inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 mRNA]16166651
C017947sodium arsenitepyrazolanthrone inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein]16166651
C017947sodium arsenitesodium arsenite results in decreased expression of BCL2L11 mRNA19822182
C017947sodium arsenitesodium arsenite results in increased expression of and affects the localization of BCL2L11 protein16166651
C017947sodium arsenitesodium arsenite results in increased expression of BCL2L11 mRNA16166651
C017947sodium arseniteBCL2L11 protein results in increased susceptibility to sodium arsenite16818494
C017947sodium arseniteSB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of BCL2L11 protein]16818494
C017947sodium arsenitesodium arsenite promotes the reaction [MAPK14 protein results in increased phosphorylation of BCL2L11 protein]16818494
C017947sodium arsenitesodium arsenite results in increased expression of BCL2L11 protein alternative form20830294
C017947sodium arsenitesodium arsenite results in increased phosphorylation of BCL2L11 protein16818494
C017947sodium arseniteTaurine inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein alternative form]20830294
D012965Sodium Chloride[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein16030430
D012965Sodium ChlorideS-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]16030430
C471405sorafenibsorafenib affects the localization of BCL2L11 protein18200035
C471405sorafenib"[sorafenib co-treated with 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] results in increased expression of BCL2L11 protein"23036488
C471405sorafenibsorafenib results in decreased expression of BCL2L11 protein16109713
C471405sorafenibsorafenib results in increased expression of BCL2L11 protein18200035
C525423SRT2183SRT2183 results in increased expression of BCL2L11 mRNA23681230
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of BCL2L11 mRNA26378955
D004113Succimer[Succimer binds to Magnetite Nanoparticles] which results in increased expression of BCL2L11 mRNA21641980
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in increased expression of BCL2L11 mRNA26378955
D013629TamoxifenTamoxifen promotes the reaction [methylselenic acid results in increased cleavage of BCL2L11 protein]18790785
D013654TaurineTaurine inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 protein alternative form]20830294
C047246temozolomideBCL2L11 mutant form inhibits the reaction [temozolomide results in increased cleavage of CASP9 protein]26418950
C047246temozolomidepyrazolanthrone inhibits the reaction [temozolomide results in increased expression of BCL2L11 mRNA]26418950
C047246temozolomidetemozolomide results in increased expression of BCL2L11 mRNA26418950
C047246temozolomidetemozolomide results in increased expression of BCL2L11 protein26418950
D013739TestosteroneTestosterone deficiency results in increased expression of BCL2L11 protein20850791
D013749Tetrachlorodibenzodioxin"2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of BCL2L11 mRNA]"21851831
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of BCL2L11 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of BCL2L11 mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of BCL2L11 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BCL2L11 mRNA15800033|2185183
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of BCL2L11 mRNA19520675
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2L11 mRNA25613284
C020809tetrathiomolybdate[Copper deficiency co-treated with tetrathiomolybdate] results in increased cleavage of BCL2L11 protein22276220
C020809tetrathiomolybdate[Copper deficiency co-treated with tetrathiomolybdate] results in increased expression of BCL2L11 protein22276220
D013853ThioacetamideThioacetamide results in increased expression of BCL2L11 mRNA23411599
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of BCL2L11 mRNA28065790
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of BCL2L11 mRNA28111298
D014118Toxins, Biological"Toxins, Biological affects the expression of BCL2L11 mRNA"19682533
C560077trametinib"[trametinib co-treated with 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide] results in increased expression of BCL2L11 protein"22733540
C560077trametinibtrametinib results in increased expression of BCL2L11 protein22733540
D014212TretinoinTretinoin results in decreased expression of BCL2L11 protein19176369
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C012589trichostatin Atrichostatin A inhibits the reaction [Nickel affects the expression of BCL2L11 mRNA]14575637
C012589trichostatin Atrichostatin A results in decreased expression of BCL2L11 mRNA24935251|2627250
C012589trichostatin Atrichostatin A results in increased expression of BCL2L11 mRNA24935251
C015559trimellitic anhydridetrimellitic anhydride results in increased expression of BCL2L11 mRNA19042947
D014302Trinitrobenzenesulfonic AcidD-JNKI-1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of BCL2L11 protein]22427801
D014302Trinitrobenzenesulfonic AcidD-JNKI-1 inhibits the reaction [[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]]22427801
D014302Trinitrobenzenesulfonic AcidTrinitrobenzenesulfonic Acid results in increased expression of BCL2L11 protein22427801
D014302Trinitrobenzenesulfonic Acid[Trinitrobenzenesulfonic Acid results in increased expression of MAPK9 protein] promotes the reaction [BCL2L11 protein binds to MAPK9 protein]22427801
C057693troglitazonetroglitazone results in decreased expression of BCL2L11 mRNA28973697
C113580U 0126U 0126 inhibits the reaction [docetaxel results in increased degradation of BCL2L11 protein]17317842
C113580U 0126"U 0126 promotes the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]"19116364
D014520UrethaneUrethane results in increased expression of BCL2L11 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of BCL2L11 mRNA23179753|2438349
D014635Valproic AcidValproic Acid affects the expression of BCL2L11 mRNA17963808
D014638VanadatesVanadates results in decreased expression of BCL2L11 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of BCL2L11 gene25560391
C551177vemurafenib[BRAF protein mutant form results in increased susceptibility to vemurafenib] which results in increased expression of BCL2L11 protein27689874
C551177vemurafenib[MET protein affects the susceptibility to HGF protein] affects the reaction [[BRAF protein mutant form results in increased susceptibility to vemurafenib] which results in increased expression of BCL2L11 protein]27689874
C029297vinylidene chloridevinylidene chloride results in increased expression of BCL2L11 mRNA26682919
D009536Niacinamide[Berberine co-treated with Niacinamide] results in increased expression of BCL2L11 mRNA26712469
D009536NiacinamideNiacinamide promotes the reaction [[Oxygen co-treated with Oxygen deficiency] results in increased expression of BCL2L11 protein]25472572
D009536NiacinamideNiacinamide results in increased expression of BCL2L11 mRNA26712469
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of BCL2L11 mRNA"27188386
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in increased expression of BCL2L11 mRNA]19509267
C111237vorinostatTNFSF10 protein promotes the reaction [vorinostat results in increased expression of BCL2L11 protein]19509267
C111237vorinostatvorinostat results in increased expression of BCL2L11 mRNA19509267|2165254
C111237vorinostatvorinostat results in increased expression of BCL2L11 protein16144943|1950926
C111237vorinostatvorinostat results in increased expression of BCL2L11 protein alternative form17351739
C111237vorinostatvorinostat results in increased expression of BCL2L11 mRNA17331788
C111237vorinostatvorinostat results in increased expression of BCL2L11 protein17331788
C009684withaferin Awithaferin A results in decreased expression of BCL2L11 protein20438634
D015032ZincZinc results in increased expression of BCL2L11 mRNA19071009
C017803zinc protoporphyrinzinc protoporphyrin results in increased expression of BCL2L11 protein27829220
C088658zoledronic acid[zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNA16996129

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI14596824  15694340  16213503  16697956  17074758  17289999  
17525735  17692808  18420585  18551131  18948948  19427863  
20085765  20627101  21132008  21199865  21507240  21671007  
22516262  23235460  23245996  23374347  23845444  24008843  
25416956  25497728  26004684  26859456  
GO:0008017microtubule binding-IBA21873635  
GO:0019901protein kinase binding-IEA-  
GO:0046982protein heterodimerization activity-IEA-  
GO:0070840dynein complex binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001701in utero embryonic development-IEA-  
GO:0001782B cell homeostasis-IEA-  
GO:0001783B cell apoptotic process-IEA-  
GO:0001822kidney development-IEA-  
GO:0001844protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-TAS-  
GO:0002262myeloid cell homeostasis-IEA-  
GO:0006915apoptotic process-TAS10381623  
GO:0007127meiosis I-IBA21873635  
GO:0007160cell-matrix adhesion-IEA-  
GO:0007283spermatogenesis-IEA-  
GO:0007420brain development-IEA-  
GO:0008584male gonad development-IEA-  
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage-IDA11546872  
GO:0030879mammary gland development-IEA-  
GO:0032464positive regulation of protein homooligomerization-IDA21041309  
GO:0034976response to endoplasmic reticulum stress-IDA22761832  
GO:0035148tube formation-IEA-  
GO:0042475odontogenesis of dentin-containing tooth-IEA-  
GO:0042981regulation of apoptotic process-TAS20371704  
GO:0043029T cell homeostasis-IEA-  
GO:0043065positive regulation of apoptotic process-IBA21873635  
GO:0043065positive regulation of apoptotic process-IMP17289999  
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-IEA-  
GO:0043525positive regulation of neuron apoptotic process-IEA-  
GO:0043583ear development-IEA-  
GO:0045787positive regulation of cell cycle-IEA-  
GO:0046620regulation of organ growth-IEA-  
GO:0048066developmental pigmentation-IEA-  
GO:0048070regulation of developmental pigmentation-IEA-  
GO:0048536spleen development-IEA-  
GO:0048538thymus development-IEA-  
GO:0048563post-embryonic animal organ morphogenesis-IEA-  
GO:0060139positive regulation of apoptotic process by virus-IEA-  
GO:0060154cellular process regulating host cell cycle in response to virus-IEA-  
GO:0070242thymocyte apoptotic process-IEA-  
GO:0071385cellular response to glucocorticoid stimulus-TAS20371704  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IGI21041309  
GO:0090200positive regulation of release of cytochrome c from mitochondria-IMP17289999  
GO:0097192extrinsic apoptotic signaling pathway in absence of ligand-IEA-  
GO:1902237positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-TAS22013210  
GO:1902263apoptotic process involved in embryonic digit morphogenesis-IEA-  
GO:1903896positive regulation of IRE1-mediated unfolded protein response-TAS22013210  
GO:2000271positive regulation of fibroblast apoptotic process-IDA11997495  
GO:2001244positive regulation of intrinsic apoptotic signaling pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005739mitochondrion-IBA21873635  
GO:0005741mitochondrial outer membrane-TAS-  
GO:0005829cytosol-TAS-  
GO:0005868cytoplasmic dynein complex-IEA-  
GO:0012505endomembrane system-IEA-  
GO:0019898extrinsic component of membrane-IEA-  
GO:0097136Bcl-2 family protein complex-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-109581ApoptosisTAS
R-HSA-109606Intrinsic Pathway for ApoptosisTAS
R-HSA-111446Activation of BIM and translocation to mitochondria TAS
R-HSA-111453BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 membersTAS
R-HSA-114452Activation of BH3-only proteinsTAS
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-193648NRAGE signals death through JNKTAS
R-HSA-193704p75 NTR receptor-mediated signallingTAS
R-HSA-204998Cell death signalling via NRAGE, NRIF and NADETAS
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-5357801Programmed Cell DeathTAS
R-HSA-5663202Diseases of signal transductionTAS
R-HSA-6802952Signaling by BRAF and RAF fusionsTAS
R-HSA-6802957Oncogenic MAPK signalingTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-73887Death Receptor SignallingTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-8862803Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease modelsTAS
R-HSA-8863678Neurodegenerative DiseasesTAS
R-HSA-8878159Transcriptional regulation by RUNX3TAS
R-HSA-8952158RUNX3 regulates BCL2L11 (BIM) transcriptionTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
28700107Cigarette smoke induces rat testicular injury via mitochondrial apoptotic pathway. (2017 Oct)He LMol Reprod Dev
27698889TGFB2 and BCL2L11 methylation in male laryngeal cancer patients. (2016 Oct)Shen ZOncol Lett