| C478160 | (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane | "(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane inhibits the reaction [Cisplatin results in decreased expression of CDK4 protein]" | 20195699 |
| C478160 | (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane | "(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane results in decreased expression of CDK4 mRNA" | 20195699 |
| C478160 | (1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane | "Cisplatin promotes the reaction [(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane results in decreased expression of CDK4 mRNA]" | 20195699 |
| C044985 | 1',2'-dihydrorotenone | "1',2'-dihydrorotenone results in decreased expression of CDK4 protein" | 24615755 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [AHR protein binds to CDK4 protein]" | 20637255 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK4 protein binds to CCND1 protein]" | 20637255 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of CDK4 protein" | 20637255 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CDK4 protein" | 23684557|2617173 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK4 protein binds to CCND1 protein]]" | 20637255 |
| C028474 | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | "Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of CDK4 protein]" | 20637255 |
| C002029 | 17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol | "17alpha-ethynylestr-5(10)-ene-3alpha,17beta-diol results in decreased expression of CDK4 protein" | 16019103 |
| C448659 | 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with vorinostat] results in decreased expression of CDK4 protein | 19440035 |
| C448659 | 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin | 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin results in decreased expression of CDK4 protein | 19440035 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CDK4 mRNA" | 26988655 |
| C511295 | 2,2',4,4'-tetrabromodiphenyl ether | "2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CDK4 protein" | 26988655 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDK4 protein] | 18296682 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetaldehyde results in increased expression of CDK4 mRNA] | 14636436|1823463 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in decreased expression of CDK4 protein] | 18951945 |
| C404910 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | "2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane results in increased expression of CDK4 protein" | 15525693 |
| C587734 | 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone | "2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in decreased expression of CDK4 protein" | 26451628 |
| C016403 | 2,4-dinitrotoluene | "2,4-dinitrotoluene affects the expression of CDK4 mRNA" | 21346803 |
| C085911 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDK4 protein] | 27312872 |
| C089946 | 2,4-thiazolidinedione | "2,4-thiazolidinedione results in decreased expression of CDK4 protein" | 15916743 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK4 mRNA" | 12376462|1452288 |
| C049584 | 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine | "2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of CDK4 protein" | 14522882 |
| C109986 | 2-aminoethoxydiphenyl borate | 2-aminoethoxydiphenyl borate inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDK4 protein] | 23958495 |
| C000589290 | 2-hydroxy-1-(2-((9-(4-methylcyclohexyl)-9H-pyrido(4',3'-4,5)pyrrolo(2,3-d)pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone | "2-hydroxy-1-(2-((9-(4-methylcyclohexyl)-9H-pyrido(4',3'-4,5)pyrrolo(2,3-d)pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone results in decreased activity of CDK4 protein" | 24526162 |
| C497101 | 2-hydroxy-9-cis-octadecenoic acid | 2-hydroxy-9-cis-octadecenoic acid results in decreased expression of CDK4 mRNA | 16027227 |
| C497101 | 2-hydroxy-9-cis-octadecenoic acid | 2-hydroxy-9-cis-octadecenoic acid results in decreased expression of CDK4 protein | 16027227 |
| C022830 | 2-methoxyestradiol | 2-methoxyestradiol results in decreased expression of CDK4 protein | 23967052 |
| C019499 | 2-nitrofluorene | 2-nitrofluorene results in increased expression of CDK4 mRNA | 15890375 |
| C022960 | 2-oxindole | 2-oxindole analog results in decreased activity of [CCND1 protein binds to CDK4 protein] | 10403840 |
| C022960 | 2-oxindole | 2-oxindole results in decreased activity of CDK4 protein | 15724842 |
| C018855 | 2-tert-butylhydroquinone | 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein] | 26878773 |
| C018855 | 2-tert-butylhydroquinone | 2-tert-butylhydroquinone results in increased expression of CDK4 protein | 26878773 |
| C560905 | 3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione | "3-(2-(dimethylamino)isopropoxy)-1-hydroxybenzo(b)naphtho(2,3-d)furan-6,11-dione results in decreased expression of CDK4 protein" | 21600193 |
| C041525 | 3,3',4,5'-tetrahydroxystilbene | "3,3',4,5'-tetrahydroxystilbene inhibits the reaction [TNF protein results in increased expression of and results in increased activity of CDK4 protein]" | 19631264 |
| C016392 | 3,3'-diindolylmethane | "3,3'-diindolylmethane results in decreased expression of CDK4 protein" | 22514694 |
| C472791 | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of CDK4 mRNA | 12958071 |
| C494914 | 3,5,3',4',5'-pentamethoxystilbene | "[3,5,3',4',5'-pentamethoxystilbene results in decreased activity of CDK4 protein] which results in decreased phosphorylation of RB1 protein" | 19916542 |
| C494914 | 3,5,3',4',5'-pentamethoxystilbene | "3,5,3',4',5'-pentamethoxystilbene results in decreased expression of and results in decreased activity of CDK4 protein" | 19916542 |
| C500067 | 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol | 3-((5-(6-((3-chlorophenyl)amino)pyrazinyl)-3-pyridinyl)amino)-1-propanol binds to and results in decreased activity of CDK4 protein | 15771433 |
| C479067 | 3-aminothioacridone | 3-aminothioacridone results in decreased activity of CDK4 protein | 15724842 |
| C479067 | 3-aminothioacridone | 3-aminothioacridone results in decreased activity of CDK4 protein | 12941380 |
| C017906 | 3-dinitrobenzene | 3-dinitrobenzene results in increased expression of CDK4 mRNA | 22841810 |
| C015392 | 3-nitropropionic acid | 3-nitropropionic acid results in increased expression of CDK4 protein | 21827787 |
| C581004 | 3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile | "3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in decreased expression of CDK4 protein" | 28834734 |
| C496751 | 4-(1H-imidazol-1-yl)retinoic acid | 4-(1H-imidazol-1-yl)retinoic acid results in decreased expression of CDK4 protein | 17145897 |
| C496751 | 4-(1H-imidazol-1-yl)retinoic acid | 4-(1H-imidazol-1-yl)retinoic acid results in decreased expression of CDK4 protein | 17145897 |
| C035207 | 4-amino-2,6-dinitrotoluene | "4-amino-2,6-dinitrotoluene affects the expression of CDK4 mRNA" | 21346803 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone promotes the reaction [CDK4 protein binds to CCND1 protein] | 18805435 |
| C016583 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CDK4 mRNA | 15890375 |
| C524814 | 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one | 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one inhibits the reaction [STK11 mutant form results in increased expression of CDK4 protein] | 24793789 |
| C524814 | 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one | 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one results in decreased expression of CDK4 protein | 24793789 |
| C573233 | 5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one | "5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one inhibits the reaction [[INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in increased expression of CDK4 protein]" | 24646949 |
| C580598 | 5-OH-BDE-47 | 5-OH-BDE-47 results in increased expression of CDK4 mRNA | 26988655 |
| C531937 | 6-O-angeloylenolin | 6-O-angeloylenolin results in decreased expression of CDK4 protein | 21192922 |
| C580599 | 6-OH-BDE-47 | 6-OH-BDE-47 results in increased expression of CDK4 mRNA | 26988655 |
| C553817 | 7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one | "7-(benzylamino)-1,3,4,8-tetrahydropyrrolo(4,3,2-de)quinolin-8(1H)-one results in decreased expression of CDK4 protein" | 19936915 |
| C559145 | 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine | "7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine results in decreased expression of CDK4 protein" | 21417417 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in decreased activity of CDK4 protein | 14653808 |
| C542662 | AC 93253 | AC 93253 results in decreased expression of CDK4 mRNA | 25912555 |
| D000079 | Acetaldehyde | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetaldehyde results in increased expression of CDK4 mRNA] | 14636436|1823463 |
| D000079 | Acetaldehyde | Acetaldehyde results in increased expression of CDK4 mRNA | 14636436|1823463 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CDK4 mRNA | 11793227 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of CDK4 mRNA | 17562736 |
| D000082 | Acetaminophen | Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein] | 28123000 |
| D000082 | Acetaminophen | Acetaminophen results in decreased expression of CDK4 protein | 25319358|2595647 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CDK4 protein | 28123000 |
| D000082 | Acetaminophen | Canertinib inhibits the reaction [Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein]] | 28123000 |
| D000082 | Acetaminophen | Canertinib inhibits the reaction [Acetaminophen results in increased expression of CDK4 protein] | 28123000 |
| C487680 | acetylbritannilatone | acetylbritannilatone analog results in decreased expression of CDK4 protein | 27262408 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CDK4 mRNA] | 19615393 |
| D020106 | Acrylamide | Acrylamide analog results in decreased expression of CDK4 protein | 17317719 |
| C096064 | actein | actein results in decreased expression of CDK4 protein | 14758092 |
| C058956 | acteoside | acteoside promotes the reaction [CDKN1A protein binds to CDK4 protein] | 17634406 |
| C058956 | acteoside | acteoside promotes the reaction [CDKN1B protein binds to CDK4 protein] | 17634406 |
| C058956 | acteoside | acteoside results in decreased activity of CDK4 protein | 17634406 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of CDK4 mRNA | 27153756 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in increased expression of CDK4 mRNA | 15890375 |
| C512484 | AG-012986 | AG-012986 results in decreased activity of CDK4 protein | 22095879 |
| C430898 | AGN 194204 | AGN 194204 results in decreased expression of CDK4 protein | 15318936|2108096 |
| C430898 | AGN 194204 | CREBBP protein inhibits the reaction [AGN 194204 results in decreased expression of CDK4 protein] | 21080969 |
| C430898 | AGN 194204 | NCOA1 protein inhibits the reaction [AGN 194204 results in decreased expression of CDK4 protein] | 21080969 |
| D000393 | Air Pollutants | Air Pollutants results in decreased expression of CDK4 protein | 28389379 |
| D000395 | Air Pollutants, Occupational | "Air Pollutants, Occupational results in decreased expression of CDK4 mRNA" | 23195993 |
| D000420 | Albuterol | Albuterol results in increased expression of CDK4 protein | 18362475 |
| C077990 | alvocidib | alvocidib results in decreased activity of CDK4 protein | 12517783 |
| C077990 | alvocidib | alvocidib results in decreased expression of CDK4 protein | 12734434 |
| C077990 | alvocidib | alvocidib results in decreased activity of CDK4 protein | 11464216 |
| D000602 | Amino Acids, Peptides, and Proteins | "Amino Acids, Peptides, and Proteins results in increased expression of CDK4 mRNA" | 23747718 |
| D017311 | Amlodipine | Amlodipine results in decreased activity of and results in decreased expression of CDK4 protein | 17217918 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CDK4 mRNA | 16483693 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CDK4 protein | 16483693 |
| D000643 | Ammonium Chloride | Ammonium Chloride results in increased expression of CDK4 mRNA | 12420312 |
| C030419 | andrographolide | andrographolide inhibits the reaction [CCND1 protein binds to CDK4 protein] | 18619950 |
| C030419 | andrographolide | andrographolide results in decreased expression of CDK4 protein | 18619950 |
| C023650 | aniline | aniline results in increased expression of CDK4 protein | 21070798 |
| D000880 | Anthraquinones | Anthraquinones analog results in decreased activity of CDK4 protein | 27473261 |
| C545357 | antroquinonol | antroquinonol results in decreased expression of and results in decreased localization of CDK4 protein | 19723512 |
| C102351 | apicidin | apicidin results in decreased expression of CDK4 mRNA | 19070610 |
| C102351 | apicidin | apicidin results in decreased expression of CDK4 protein | 18313654|1907061 |
| D001115 | Arecoline | Arecoline results in increased expression of CDK4 mRNA | 21741983 |
| D001115 | Arecoline | Arecoline results in increased expression of CDK4 protein | 21741983 |
| D001151 | Arsenic | Arsenic affects the methylation of CDK4 gene | 25304211 |
| D001151 | Arsenic | Arsenic results in increased expression of CDK4 mRNA | 20654705 |
| D001151 | Arsenic | [silybin co-treated with Arsenic] results in decreased expression of CDK4 protein | 25868784 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of CDK4 mRNA | 17530438|1976963 |
| D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein] | 21621607 |
| D001241 | Aspirin | Aspirin results in decreased expression of CDK4 mRNA | 20457246 |
| D001280 | Atrazine | Atrazine results in decreased expression of CDK4 mRNA | 22378314 |
| D001374 | Azacitidine | Azacitidine analog results in decreased expression of CDK4 protein | 18324645 |
| C517975 | AZD 6244 | AZD 6244 results in decreased expression of CDK4 protein | 17876044 |
| C517975 | AZD 6244 | Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CDK4 protein] | 17876044 |
| C547126 | AZM551248 | AZM551248 results in increased expression of CDK4 mRNA | 22323515 |
| C006680 | baicalein | baicalein results in increased expression of CDK4 protein | 22820424 |
| C487081 | belinostat | belinostat results in decreased expression of CDK4 mRNA | 19606018 |
| D019817 | Benzoic Acid | Benzoic Acid analog results in decreased activity of [CCND1 protein binds to CDK4 protein] | 10403840 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CDK4 mRNA | 19027820 |
| D001564 | Benzo(a)pyrene | CDK4 protein promotes the reaction [Benzo(a)pyrene results in increased expression of E2F1 protein] | 16406622 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of CDK4 mRNA | 19770486 |
| D001599 | Berberine | Berberine results in decreased expression of CDK4 protein | 16505103 |
| D004958 | Estradiol | Estradiol inhibits the reaction [CDK4 protein binds to CDKN1A protein] | 9705214 |
| D004958 | Estradiol | Estradiol results in increased activity of CDK4 protein | 9705214 |
| D004958 | Estradiol | [Estradiol results in increased expression of CDC25A protein] which results in decreased phosphorylation of CDK4 protein | 9705214 |
| D004958 | Estradiol | Estradiol results in increased expression of CDK4 mRNA | 21826169|2309414 |
| D004958 | Estradiol | Estradiol results in increased expression of CDK4 protein | 19361625 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased expression of CDK4 protein] | 19361625 |
| D004958 | Estradiol | IGF1R mutant form inhibits the reaction [Estradiol results in increased expression of CDK4 mRNA] | 23094148 |
| D004958 | Estradiol | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased activity of CDK4 protein] | 9705214 |
| D004958 | Estradiol | Tetrachlorodibenzodioxin promotes the reaction [Estradiol inhibits the reaction [CDK4 protein binds to CDKN1A protein]] | 9705214 |
| D004958 | Estradiol | Estradiol inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CDK4 mRNA] | 19874833 |
| D004958 | Estradiol | Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA] | 19874833 |
| D001629 | Bezafibrate | Bezafibrate results in increased expression of CDK4 mRNA | 15447978 |
| C543008 | bis(4-hydroxyphenyl)sulfone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDK4 mRNA | 28628672 |
| C006780 | bisphenol A | bisphenol A results in increased expression of CDK4 mRNA | 21826169 |
| C006780 | bisphenol A | bisphenol A results in increased expression of CDK4 protein | 19361625|2127795 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDK4 protein] | 19361625 |
| C006780 | bisphenol A | bisphenol A affects the expression of CDK4 mRNA | 25181051 |
| C000611646 | bisphenol F | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CDK4 mRNA | 28628672 |
| C492810 | BL1521 | BL1521 results in decreased expression of CDK4 protein | 15733867 |
| C545990 | BMS 754807 | [CDK4 mutant form co-treated with CDK6 mutant form] results in increased susceptibility to BMS 754807 | 24986516 |
| C545990 | BMS 754807 | [[CDK4 mutant form co-treated with CDK6 mutant form] results in increased susceptibility to BMS 754807] which results in decreased phosphorylation of RPS6KB1 protein | 24986516 |
| C023623 | brassinolide | brassinolide results in decreased expression of CDK4 protein | 20833159 |
| D002038 | Bungarotoxins | Bungarotoxins inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D002066 | Busulfan | Busulfan results in decreased expression of CDK4 mRNA | 15388331 |
| C026105 | butylidenephthalide | butylidenephthalide results in decreased expression of CDK4 protein | 16987298 |
| C026105 | butylidenephthalide | butylidenephthalide results in decreased expression of CDK4 protein | 16987298 |
| D002087 | Butyrates | Butyrates results in decreased expression of CDK4 protein | 15978324 |
| D020148 | Butyric Acid | Butyric Acid results in decreased expression of CDK4 mRNA | 12800193 |
| C028031 | cadmium acetate | cadmium acetate affects the expression of CDK4 mRNA | 16249259 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of CDK4 mRNA | 25851441 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased expression of CDK4 mRNA | 20219890 |
| D019256 | Cadmium Chloride | [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein | 12135628 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in decreased expression of CDK4 mRNA | 18636176 |
| D002110 | Caffeine | Caffeine results in decreased expression of CDK4 mRNA | 11793227 |
| D002110 | Caffeine | Caffeine results in decreased activity of [CCND1 protein binds to CDK4 protein] | 15126379 |
| C420268 | Canertinib | Canertinib inhibits the reaction [Acetaminophen promotes the reaction [[CCND1 protein binds to and results in increased activity of CDK4 protein] which results in increased phosphorylation of RB1 protein]] | 28123000 |
| C420268 | Canertinib | Canertinib inhibits the reaction [Acetaminophen results in increased expression of CDK4 protein] | 28123000 |
| D002211 | Capsaicin | Capsaicin results in decreased expression of CDK4 mRNA | 16278290 |
| D002211 | Capsaicin | [Capsaicin results in decreased expression of CCND1] inhibits the reaction [CDK4 results in increased phosphorylation of RB1 protein] | 14744780 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of CDK4 protein | 17298859 |
| D002259 | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone promotes the reaction [CDKN1B protein binds to CDK4 protein] | 19819288 |
| C038590 | cardanol | cardanol results in decreased expression of CDK4 mRNA | 26694491 |
| C099555 | CD 437 | CD 437 results in decreased expression of CDK4 mRNA | 12958071 |
| D000068579 | Celecoxib | Celecoxib results in decreased expression of CDK4 protein | 16136956 |
| D002713 | Chlorine | [Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA | 18636392 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in decreased expression of CDK4 mRNA | 23940686 |
| C074702 | chromium hexavalent ion | Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein] | 21621607 |
| C074702 | chromium hexavalent ion | chromium hexavalent ion results in decreased expression of CDK4 protein | 21621607 |
| C039671 | ciglitazone | ciglitazone results in decreased expression of CDK4 protein | 21080969 |
| C039671 | ciglitazone | CREBBP protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein] | 21080969 |
| C039671 | ciglitazone | NCOA1 protein inhibits the reaction [ciglitazone results in decreased expression of CDK4 protein] | 21080969 |
| C039671 | ciglitazone | ciglitazone results in decreased expression of CDK4 mRNA | 20578043 |
| D002994 | Clofibrate | Clofibrate results in decreased expression of CDK4 protein | 21080969 |
| D002994 | Clofibrate | CREBBP protein inhibits the reaction [Clofibrate results in decreased expression of CDK4 protein] | 21080969 |
| D002994 | Clofibrate | NCOA1 protein inhibits the reaction [Clofibrate results in decreased expression of CDK4 protein] | 21080969 |
| D002995 | Clofibric Acid | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDK4 mRNA | 17602206 |
| D003022 | Clotrimazole | Clotrimazole results in decreased expression of CDK4 | 20724915 |
| D003024 | Clozapine | Clozapine results in increased expression of CDK4 mRNA | 15860345 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of CDK4 mRNA | 19376846 |
| D003042 | Cocaine | Cocaine affects the expression of CDK4 mRNA | 18355967 |
| D003345 | Corticosterone | Corticosterone inhibits the reaction [CDKN1A protein binds to CDK4 protein] | 12807724 |
| D003345 | Corticosterone | Corticosterone promotes the reaction [CDKN1B protein binds to CDK4 protein] | 12807724 |
| D003345 | Corticosterone | Corticosterone results in decreased activity of CDK4 protein | 12807724 |
| D003345 | Corticosterone | Corticosterone results in decreased expression of CDK4 protein | 12807724 |
| D003471 | Cuprizone | Cuprizone results in increased expression of CDK4 mRNA | 26577399 |
| D003474 | Curcumin | Curcumin analog results in decreased expression of CDK4 mRNA | 26409325 |
| D003474 | Curcumin | Curcumin results in decreased expression of CDK4 protein | 18156803|2421127 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in decreased expression of CDK4 mRNA | 28414124 |
| C057862 | cyanoginosin LR | cyanoginosin LR results in decreased expression of CDK4 protein | 28414124 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of CDK4 mRNA | 25562108 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of CDK4 mRNA | 20106945 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of CDK4 mRNA | 19770486 |
| C004742 | daidzein | daidzein results in decreased activity of CDK4 protein | 21161820 |
| D000069439 | Dasatinib | [NVP-AEW541 co-treated with Dasatinib] results in decreased expression of CDK4 protein | 20664932 |
| D003634 | DDT | DDT results in increased expression of CDK4 protein | 23684557 |
| C107676 | deguelin | deguelin metabolite results in decreased expression of CDK4 protein | 19139008 |
| C107676 | deguelin | deguelin results in decreased expression of CDK4 protein | 19139008|1933672 |
| C548688 | dehydroglyasperin C | dehydroglyasperin C results in decreased expression of CDK4 protein | 23298457 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDK4 mRNA | 28628672 |
| D003907 | Dexamethasone | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CDK4 mRNA | 28628672 |
| D003907 | Dexamethasone | "5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one inhibits the reaction [[INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in increased expression of CDK4 protein]" | 24646949 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of CDK4 mRNA | 21041162 |
| D003907 | Dexamethasone | [INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in increased expression of CDK4 protein | 24646949 |
| D003976 | Diazinon | Diazinon results in increased methylation of CDK4 gene | 22964155 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in increased expression of CDK4 mRNA | 22179484 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of CDK4 mRNA | 17361019|2126653 |
| D002945 | Cisplatin | "(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane inhibits the reaction [Cisplatin results in decreased expression of CDK4 protein]" | 20195699 |
| D002945 | Cisplatin | "Cisplatin promotes the reaction [(1,2-bis(1,2-benzisoselenazolone-3(2H)-ketone))ethane results in decreased expression of CDK4 mRNA]" | 20195699 |
| D002945 | Cisplatin | Cisplatin results in decreased activity of [CCND1 protein binds to CDK4 protein] | 21592546 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of CDK4 protein | 20195699 |
| D002945 | Cisplatin | Cisplatin results in increased expression of CDK4 mRNA | 27594783 |
| D002945 | Cisplatin | Cisplatin results in decreased expression of CDK4 mRNA | 21151649 |
| C036042 | dicyclohexyl phthalate | dicyclohexyl phthalate affects the expression of CDK4 mRNA | 26924002 |
| C552234 | didymin | didymin results in decreased expression of CDK4 protein | 27899290 |
| C552234 | didymin | locostatin inhibits the reaction [didymin results in decreased expression of CDK4 protein] | 27899290 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in decreased expression of CDK4 mRNA | 19874833 |
| D004051 | Diethylhexyl Phthalate | Diethylhexyl Phthalate results in increased expression of CDK4 mRNA | 25701202 |
| D004051 | Diethylhexyl Phthalate | Estradiol inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of CDK4 mRNA] | 19874833 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CDK4 mRNA | 17602206 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 mRNA | 12616621 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 protein | 12616621 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA | 12616621 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein | 12616621 |
| D004052 | Diethylnitrosamine | Diethylnitrosamine results in increased expression of CDK4 protein | 11831363|1982219 |
| D004052 | Diethylnitrosamine | thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of CDK4 protein] | 24012840 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in decreased expression of CDK4 mRNA | 21041162 |
| D004054 | Diethylstilbestrol | Diethylstilbestrol results in increased expression of CDK4 mRNA | 15890375 |
| C011612 | diethyl sulfate | diethyl sulfate affects the expression of CDK4 protein | 23887207 |
| D004079 | Dihydro-beta-Erythroidine | Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D002117 | Calcitriol | Calcitriol promotes the reaction [CDKN1B protein binds to CDK4 protein] | 16322758 |
| C472511 | dimethylarsinous acid | dimethylarsinous acid results in decreased expression of CDK4 mRNA | 20886546 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | "9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDK4 mRNA" | 12376462 |
| D004128 | Dimethylnitrosamine | Dimethylnitrosamine results in increased expression of CDK4 mRNA | 15890375 |
| D004281 | Docosahexaenoic Acids | Docosahexaenoic Acids results in decreased expression of CDK4 mRNA | 16623957 |
| D004317 | Doxorubicin | Doxorubicin promotes the reaction [AZD 6244 results in decreased expression of CDK4 protein] | 17876044 |
| D004317 | Doxorubicin | [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK4 protein | 19789217 |
| D004391 | Dust | Dust results in decreased expression of CDK4 mRNA | 17805423 |
| D004642 | Emodin | Emodin results in decreased expression of CDK4 mRNA | 16045814 |
| D004791 | Enzyme Inhibitors | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CDK4 protein | 23301498 |
| C045651 | epigallocatechin gallate | epigallocatechin gallate results in decreased expression of CDK4 protein | 15142168 |
| D000069347 | Erlotinib Hydrochloride | Erlotinib Hydrochloride results in decreased phosphorylation of CDK4 protein | 21195724 |
| C007628 | esculetin | esculetin promotes the reaction [CDKN1A protein binds to CDK4 protein] | 21600278 |
| C007628 | esculetin | esculetin results in decreased expression of CDK4 protein | 21600278 |
| C007628 | esculetin | SB 203580 inhibits the reaction [esculetin results in decreased expression of CDK4 protein] | 21600278 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of CDK4 mRNA | 12655037|1614062 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of CDK4 mRNA | 16174780 |
| C032773 | ethyl caffeate | ethyl caffeate affects the expression of CDK4 protein | 24892518 |
| D005411 | Flame Retardants | Flame Retardants results in decreased expression of CDK4 protein | 18952254 |
| D005419 | Flavonoids | Flavonoids results in decreased expression of CDK4 mRNA | 18035473 |
| D015073 | 2-Acetylaminofluorene | 2-Acetylaminofluorene results in increased activity of CDK4 protein | 15158336 |
| D005485 | Flutamide | Flutamide results in decreased expression of CDK4 mRNA | 24793618 |
| C473894 | fujiflavone P40 | fujiflavone P40 results in increased expression of CDK4 mRNA | 14656947 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in increased expression of CDK4 protein] | 19361625 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased expression of CDK4 protein] | 19361625 |
| C039281 | furan | furan results in increased methylation of CDK4 gene | 22079235 |
| C037032 | galangin | galangin results in decreased expression of CDK4 protein | 25450235 |
| C001277 | geldanamycin | geldanamycin results in decreased expression of CDK4 protein | 28673683 |
| D019833 | Genistein | Genistein results in decreased activity of CDK4 protein | 21161820 |
| D005839 | Gentamicins | Gentamicins results in increased expression of CDK4 mRNA | 22061828 |
| C007845 | gingerol | gingerol results in decreased expression of CDK4 protein | 18058799 |
| D005897 | Glafenine | Glafenine results in increased expression of CDK4 mRNA | 24136188 |
| D005978 | Glutathione | Glutathione deficiency results in increased expression of CDK4 mRNA | 15345336 |
| C086566 | glycitein | glycitein results in decreased activity of CDK4 protein | 21161820 |
| C010974 | glyphosate | glyphosate results in increased expression of CDK4 protein | 24073338 |
| D005679 | G(M3) Ganglioside | G(M3) Ganglioside analog results in decreased expression of CDK4 protein | 17317719 |
| C103280 | goniothalamin | goniothalamin results in decreased expression of CDK4 mRNA | 26522230 |
| C568713 | GSK1210151A | GSK1210151A results in decreased expression of CDK4 protein | 26254443 |
| D006220 | Haloperidol | Haloperidol results in increased expression of CDK4 mRNA | 15860345 |
| C013015 | hesperetin | hesperetin promotes the reaction [CDK4 protein binds to CDKN1A protein] | 17927510 |
| C013015 | hesperetin | hesperetin results in decreased expression of CDK4 | 17927510 |
| C089796 | hexabromocyclododecane | hexabromocyclododecane results in increased expression of CDK4 mRNA | 22179484 |
| D018738 | Hexamethonium | Hexamethonium inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| C070164 | homocastasterone | homocastasterone results in decreased expression of CDK4 protein | 20833159 |
| D017313 | Fenretinide | Fenretinide results in increased expression of CDK4 mRNA | 28973697 |
| C403899 | HS 1030 | HS 1030 results in decreased expression of CDK4 protein | 15202011 |
| C403900 | HS 1183 | HS 1183 results in decreased expression of CDK4 protein | 15202011 |
| C503536 | HS-1199 | HS-1199 results in decreased expression of CDK4 protein | 15202011 |
| C479128 | HS 1200 | HS 1200 results in decreased expression of CDK4 protein | 15202011 |
| D006812 | Humic Substances | Humic Substances results in decreased expression of CDK4 protein | 18683188 |
| D006830 | Hydralazine | [Hydralazine co-treated with Valproic Acid] results in increased expression of CDK4 mRNA | 17183730 |
| D006918 | Hydroxyurea | Hydroxyurea results in decreased expression of CDK4 protein | 16356682 |
| D007069 | Ifosfamide | CDK4 mRNA results in decreased susceptibility to Ifosfamide | 15736417 |
| D007069 | Ifosfamide | CDK4 protein results in decreased susceptibility to Ifosfamide | 15736417 |
| D000068877 | Imatinib Mesylate | [Imatinib Mesylate co-treated with tetraarsenic tetrasulfide] results in decreased expression of CDK4 mRNA | 19208803 |
| D000068877 | Imatinib Mesylate | Imatinib Mesylate results in decreased expression of CDK4 mRNA | 19208803 |
| C016517 | indole-3-carbinol | indole-3-carbinol analog results in decreased activity of CDK4 protein | 20570586 |
| C016517 | indole-3-carbinol | indole-3-carbinol analog results in increased expression of CDK4 protein | 20570586 |
| C016517 | indole-3-carbinol | indole-3-carbinol results in decreased expression of CDK4 | 16082211 |
| D007213 | Indomethacin | Indomethacin results in decreased expression of CDK4 protein | 15786552 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDK4 mRNA | 28628672 |
| D007213 | Indomethacin | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CDK4 mRNA | 28628672 |
| D007213 | Indomethacin | Indomethacin results in increased expression of CDK4 mRNA | 28201806 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CDK4 mRNA | 25613284 |
| C506002 | ircinin-1 | ircinin-1 results in decreased expression of CDK4 mRNA | 16163705 |
| C506002 | ircinin-1 | ircinin-1 results in decreased expression of CDK4 protein | 16163705 |
| C551631 | isoangustone A | isoangustone A results in decreased expression of CDK4 protein | 21429724 |
| C551631 | isoangustone A | isoangustone A results in decreased expression of CDK4 protein | 21429724 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CDK4 mRNA | 28628672 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of CDK4 mRNA | 28628672 |
| D015056 | 1-Methyl-3-isobutylxanthine | "5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-methyl)-piperidinyl)-4H-1-benzopyran-4-one inhibits the reaction [[INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in increased expression of CDK4 protein]" | 24646949 |
| D015056 | 1-Methyl-3-isobutylxanthine | [INS1 protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone] results in increased expression of CDK4 protein | 24646949 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound inhibits the reaction [STK11 mutant form results in increased expression of CDK4 protein] | 24793789 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound promotes the reaction [ponatinib results in decreased expression of CDK4 protein] | 25053825 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound promotes the reaction [quizartinib results in decreased expression of CDK4 protein] | 25053825 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of CDK4 mRNA | 25762632|2596192 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound results in decreased expression of CDK4 protein | 24793789|2505382 |
| C561695 | (+)-JQ1 compound | ponatinib promotes the reaction [(+)-JQ1 compound results in decreased expression of CDK4 protein] | 25053825 |
| C561695 | (+)-JQ1 compound | quizartinib promotes the reaction [(+)-JQ1 compound results in decreased expression of CDK4 protein] | 25053825 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound affects the expression of CDK4 | 24394663 |
| C561695 | (+)-JQ1 compound | (+)-JQ1 compound affects the expression of CDK4 protein | 27440272 |
| C410337 | K 7174 | K 7174 results in decreased expression of CDK4 mRNA | 24086573 |
| C572783 | kuguacin J | kuguacin J results in decreased expression of CDK4 protein | 22266361 |
| C500368 | labedipinedilol A | labedipinedilol A results in decreased expression of CDK4 protein | 19056458 |
| D007854 | Lead | Lead affects the expression of CDK4 mRNA | 28903495 |
| D007854 | Lead | Lead results in increased expression of CDK4 mRNA | 19921347 |
| D008012 | Lidocaine | Lidocaine affects the expression of CDK4 mRNA | 18931217 |
| C482199 | lipopolysaccharide, E coli O55-B5 | "[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CDK4 mRNA" | 20371263 |
| C529490 | locostatin | locostatin inhibits the reaction [didymin results in decreased expression of CDK4 protein] | 27899290 |
| D008148 | Lovastatin | Lovastatin results in decreased expression of CDK4 mRNA | 20578043 |
| D008148 | Lovastatin | Lovastatin results in decreased expression of CDK4 protein | 20578043 |
| C015329 | lycopene | lycopene results in decreased expression of CDK4 protein | 17337101 |
| C005498 | magnolol | magnolol results in decreased expression of CDK4 mRNA | 23274740 |
| C005498 | magnolol | magnolol results in decreased expression of CDK4 protein | 23274740 |
| C005095 | malachite green | [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 mRNA | 12616621 |
| C005095 | malachite green | [Diethylnitrosamine co-treated with malachite green] results in increased expression of CDK4 protein | 12616621 |
| D008550 | Melatonin | Melatonin results in decreased expression of CDK4 mRNA | 21108658 |
| D008550 | Melatonin | Melatonin results in decreased expression of CDK4 protein | 21108658 |
| D008555 | Melitten | Melitten results in decreased expression of CDK4 protein | 26189965 |
| C005108 | metanil yellow | [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 mRNA | 12616621 |
| C005108 | metanil yellow | [Diethylnitrosamine co-treated with metanil yellow] results in increased expression of CDK4 protein | 12616621 |
| D008701 | Methapyrilene | Methapyrilene results in increased expression of CDK4 mRNA | 15890375 |
| D008727 | Methotrexate | Methotrexate results in decreased expression of CDK4 mRNA | 21678067 |
| D008731 | Methoxychlor | Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CDK4 mRNA] | 19615393 |
| D008731 | Methoxychlor | Methoxychlor metabolite results in increased expression of CDK4 protein | 15525693 |
| D008731 | Methoxychlor | Methoxychlor results in decreased expression of CDK4 mRNA | 19615393 |
| D008731 | Methoxychlor | Methoxychlor results in decreased expression of CDK4 protein | 19615393 |
| D008731 | Methoxychlor | Methoxychlor results in increased expression of CDK4 protein | 15525693 |
| D008769 | Methylnitronitrosoguanidine | [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of CDK4 protein | 12135628 |
| D008769 | Methylnitronitrosoguanidine | Methylnitronitrosoguanidine results in increased expression of CDK4 protein | 21628965 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium results in decreased expression of CDK4 protein | 26768367 |
| D015655 | 1-Methyl-4-phenylpyridinium | 1-Methyl-4-phenylpyridinium results in decreased expression of CDK4 protein | 26558463 |
| C008493 | methylselenic acid | methylselenic acid promotes the reaction [CDKN2A protein binds to CDK4 protein binds to CCND1 protein] | 17847021 |
| C008493 | methylselenic acid | methylselenic acid results in decreased activity of [CDKN2A protein binds to CDK4 protein binds to CCND1 protein] | 17847021 |
| C008493 | methylselenic acid | methylselenic acid results in decreased expression of CDK4 mRNA | 11830524|1251777 |
| C063855 | microcystin RR | microcystin RR results in decreased expression of CDK4 protein | 19111056 |
| C016599 | mono-(2-ethylhexyl)phthalate | Estradiol inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA] | 19874833 |
| C016599 | mono-(2-ethylhexyl)phthalate | mono-(2-ethylhexyl)phthalate results in decreased expression of CDK4 mRNA | 19874833 |
| C406082 | monomethylarsonous acid | monomethylarsonous acid results in increased expression of CDK4 mRNA | 20024957 |
| C517284 | monomethyl phthalate | monomethyl phthalate affects the expression of CDK4 mRNA | 26924002 |
| C479831 | N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea | "[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein]" | 20540935 |
| D037742 | Nanotubes, Carbon | "[Nanotubes, Carbon co-treated with Nitrogen] results in increased expression of CDK4 protein" | 25797581 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of CDK4 mRNA" | 15585362 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of CDK4 protein" | 28673683 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of CDK4 mRNA" | 25511174 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog results in increased expression of CDK4 mRNA" | 25554681 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of CDK4 mRNA" | 25554681 |
| C005274 | naringin | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in increased expression of CDK4 protein] | 18296682 |
| C005274 | naringin | HRAS protein affects the reaction [naringin results in decreased expression of CDK4 protein] | 18296682 |
| C005274 | naringin | naringin promotes the reaction [CDKN1A protein binds to CDK4 protein] | 18296682 |
| C005274 | naringin | naringin results in decreased expression of and results in decreased activity of CDK4 protein | 18296682 |
| C005274 | naringin | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [naringin results in decreased expression of CDK4 protein] | 18951945 |
| C005274 | naringin | HRAS protein affects the reaction [naringin results in decreased expression of CDK4 protein] | 18951945 |
| C005274 | naringin | naringin promotes the reaction [CDKN1A protein binds to CDK4 protein] | 18951945 |
| C005274 | naringin | naringin results in decreased expression of and results in decreased activity of CDK4 protein | 18951945 |
| C005274 | naringin | RAF1 protein affects the reaction [naringin results in decreased expression of CDK4 protein] | 18951945 |
| C051752 | nefazodone | nefazodone results in increased expression of CDK4 mRNA | 24136188 |
| D009532 | Nickel | Nickel results in decreased expression of CDK4 mRNA | 23195993 |
| C022838 | nickel chloride | nickel chloride affects the expression of CDK4 mRNA | 22546817 |
| D009538 | Nicotine | Bungarotoxins inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D009538 | Nicotine | Dihydro-beta-Erythroidine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D009538 | Nicotine | Hexamethonium inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D009538 | Nicotine | Nicotine promotes the reaction [CDK4 protein binds to CCND1 protein] | 18805435 |
| D009538 | Nicotine | Nicotine promotes the reaction [NFATC2 protein results in decreased expression of CDK4 protein] | 15231866 |
| D009538 | Nicotine | Nicotine results in decreased expression of CDK4 protein | 15231866 |
| D009538 | Nicotine | Tubocurarine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| D009538 | Nicotine | Nicotine results in decreased expression of CDK4 mRNA | 17135361 |
| D009538 | Nicotine | Nicotine results in decreased expression of CDK4 protein | 17135361 |
| D009584 | Nitrogen | "[Nanotubes, Carbon co-treated with Nitrogen] results in increased expression of CDK4 protein" | 25797581 |
| C000591546 | NKCT1 protein, Naja kaouthia | "NKCT1 protein, Naja kaouthia analog results in decreased phosphorylation of CDK4 protein" | 28322778 |
| C466914 | NU6102 | NU6102 binds to CDK4 protein | 15928920 |
| C501177 | NVP-AEW541 | [NVP-AEW541 co-treated with Dasatinib] results in decreased expression of CDK4 protein | 20664932 |
| C000594117 | ON123300 | ON123300 results in increased expression of CDK4 mRNA | 26873845 |
| C000594117 | ON123300 | ON123300 results in decreased activity of CDK4 protein | 26174628 |
| D010126 | Ozone | [Ozone co-treated with Chlorine] results in decreased expression of CDK4 mRNA | 18636392 |
| C500026 | palbociclib | CDK4 protein results in decreased susceptibility to palbociclib | 22711607 |
| C500026 | palbociclib | CDK4 protein results in increased susceptibility to palbociclib | 22761470 |
| C500026 | palbociclib | palbociclib inhibits the reaction [[CDK4 protein binds to CCND1 protein] which results in increased phosphorylation of SHOX2 protein] | 22094256 |
| C500026 | palbociclib | palbociclib promotes the reaction [CCND1 protein binds to CDKN1B protein binds to CDK4 protein] | 20473330 |
| C500026 | palbociclib | palbociclib promotes the reaction [CDK4 protein binds to CCND1 protein] | 23708653 |
| C500026 | palbociclib | palbociclib results in increased expression of CDK4 protein | 22869556 |
| C500026 | palbociclib | [CDKN2A gene mutant form results in increased expression of CDK4 protein] which results in increased susceptibility to palbociclib | 24098593 |
| C500026 | palbociclib | palbociclib analog results in decreased activity of CDK4 protein | 15542782 |
| C500026 | palbociclib | palbociclib results in decreased activity of CDK4 protein | 26174628 |
| C500026 | palbociclib | palbociclib results in decreased expression of CDK4 | 22508966 |
| C482884 | panduratin A | panduratin A results in decreased expression of CDK4 protein | 16497706 |
| D052638 | Particulate Matter | Particulate Matter results in decreased expression of CDK4 mRNA | 28366736 |
| C074968 | pentaacetyl geniposide | pentaacetyl geniposide inhibits the reaction [CCND1 protein binds to CDK4 protein] | 15975050 |
| D010416 | Pentachlorophenol | Pentachlorophenol results in increased expression of CDK4 mRNA | 19442831 |
| D010416 | Pentachlorophenol | Pentachlorophenol results in increased expression of CDK4 protein | 19442831 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of CDK4 mRNA | 23091169 |
| D010656 | Phenylephrine | Phenylephrine results in increased expression of CDK4 protein | 15603588 |
| C049032 | pinosylvin | pinosylvin results in decreased expression of CDK4 protein | 23333577 |
| C008922 | piperine | piperine inhibits the reaction [IL2 protein results in increased expression of CDK4 protein] | 25655587 |
| C498077 | piperlonguminine | piperlonguminine results in decreased expression of CDK4 protein | 29109039 |
| D010882 | Piperonyl Butoxide | Piperonyl Butoxide results in increased expression of CDK4 mRNA | 15890375 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of CDK4 mRNA | 18445702 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of CDK4 mRNA | 16377806|1830175 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of CDK4 protein | 17483499 |
| C006253 | pirinixic acid | PPARA protein affects the reaction [pirinixic acid results in increased expression of CDK4 protein] | 17483499 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of CDK4 mRNA | 15890375 |
| D010936 | Plant Extracts | Plant Extracts results in decreased expression of CDK4 mRNA | 24677778 |
| D010936 | Plant Extracts | Plant Extracts results in decreased expression of CDK4 protein | 21429724 |
| D010936 | Plant Extracts | Plant Extracts inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein] | 27723467 |
| D010936 | Plant Extracts | Plant Extracts results in decreased expression of CDK4 protein | 21429724 |
| C443641 | poly(propyleneimine) | poly(propyleneimine) analog results in increased expression of CDK4 mRNA | 16308212 |
| C545373 | ponatinib | (+)-JQ1 compound promotes the reaction [ponatinib results in decreased expression of CDK4 protein] | 25053825 |
| C545373 | ponatinib | ponatinib promotes the reaction [(+)-JQ1 compound results in decreased expression of CDK4 protein] | 25053825 |
| C545373 | ponatinib | ponatinib results in decreased expression of CDK4 protein | 25053825 |
| D011374 | Progesterone | Progesterone results in increased expression of CDK4 mRNA | 19847363 |
| D011441 | Propylthiouracil | Propylthiouracil results in increased expression of CDK4 mRNA | 24780913 |
| C573121 | ProstaCaid | ProstaCaid results in decreased expression of CDK4 mRNA | 21468543 |
| C107773 | pterostilbene | pterostilbene results in decreased expression of CDK4 protein | 20398797 |
| D011748 | Pyrogallol | Pyrogallol results in decreased expression of CDK4 mRNA | 20362636 |
| D011748 | Pyrogallol | Silymarin inhibits the reaction [Pyrogallol results in decreased expression of CDK4 mRNA] | 20362636 |
| C020972 | pyrrolidine dithiocarbamic acid | pyrrolidine dithiocarbamic acid results in decreased expression of CDK4 protein | 14603533 |
| D011794 | Quercetin | Quercetin inhibits the reaction [TNF protein results in increased activity of CDK4 protein] | 12589822 |
| D011794 | Quercetin | Quercetin inhibits the reaction [TNF protein results in increased expression of CDK4 protein] | 12589822 |
| D011794 | Quercetin | Quercetin results in decreased expression of CDK4 mRNA | 14715546|1530943 |
| C544967 | quizartinib | (+)-JQ1 compound promotes the reaction [quizartinib results in decreased expression of CDK4 protein] | 25053825 |
| C544967 | quizartinib | quizartinib promotes the reaction [(+)-JQ1 compound results in decreased expression of CDK4 protein] | 25053825 |
| C544967 | quizartinib | quizartinib results in decreased expression of CDK4 protein | 25053825 |
| C059514 | resveratrol | resveratrol affects the activity of [CCND1 protein co-treated with CDK4 protein] | 12392819 |
| C059514 | resveratrol | resveratrol affects the expression of CDK4 protein | 12392819 |
| C059514 | resveratrol | resveratrol inhibits the reaction [TNF protein results in increased expression of and results in increased activity of CDK4 protein] | 16317118 |
| C059514 | resveratrol | resveratrol promotes the reaction [TNF promotes the reaction [CDKN1A protein binds to CDK4 protein]] | 16317118 |
| C059514 | resveratrol | resveratrol results in decreased activity of [CCND1 protein binds to CDK4 protein] | 17050787 |
| C059514 | resveratrol | resveratrol results in decreased expression of [CCND1 protein binds to CDK4 protein] | 11481417 |
| C059514 | resveratrol | resveratrol results in decreased expression of CDK4 mRNA | 12569576 |
| C059514 | resveratrol | resveratrol results in decreased expression of CDK4 protein | 11481417|1705078 |
| C059514 | resveratrol | resveratrol results in decreased expression of CDK4 mRNA | 25338179 |
| C059514 | resveratrol | resveratrol results in decreased expression of CDK4 protein | 15122319 |
| D019438 | Ritonavir | Ritonavir results in decreased expression of CDK4 mRNA | 19386116 |
| D019438 | Ritonavir | Ritonavir results in decreased expression of CDK4 protein | 16551874 |
| C089730 | rosiglitazone | rosiglitazone results in decreased expression of CDK4 protein | 20210794 |
| C089730 | rosiglitazone | rosiglitazone results in increased expression of CDK4 mRNA | 17639046 |
| C085746 | rottlerin | [sorafenib co-treated with rottlerin] results in decreased expression of CDK4 protein | 16959960 |
| C039961 | S-(1,2-dichlorovinyl)cysteine | "S-(1,2-dichlorovinyl)cysteine results in increased expression of CDK4 protein" | 16495211 |
| C093642 | SB 203580 | SB 203580 inhibits the reaction [esculetin results in decreased expression of CDK4 protein] | 21600278 |
| D012643 | Selenium | Selenium deficiency results in decreased expression of CDK4 mRNA | 11925459 |
| D012643 | Selenium | Selenium results in increased expression of CDK4 mRNA | 19244175 |
| C440975 | silybin | [silybin co-treated with Arsenic] results in decreased expression of CDK4 protein | 25868784 |
| D012838 | Silymarin | Silymarin inhibits the reaction [Pyrogallol results in decreased expression of CDK4 mRNA] | 20362636 |
| D019821 | Simvastatin | Simvastatin results in decreased expression of CDK4 protein | 20878096 |
| D019821 | Simvastatin | Simvastatin results in decreased activity of CDK4 protein | 18804536 |
| D020123 | Sirolimus | Sirolimus results in decreased expression of CDK4 protein | 22761470 |
| D012906 | Smoke | Smoke analog results in increased expression of CDK4 protein | 26506537 |
| C017947 | sodium arsenite | 2-tert-butylhydroquinone inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein] | 26878773 |
| C017947 | sodium arsenite | JUN protein promotes the reaction [sodium arsenite results in increased expression of CDK4 protein] | 21726611 |
| C017947 | sodium arsenite | MAPK8 protein promotes the reaction [sodium arsenite results in increased expression of CDK4 protein] | 21726611 |
| C017947 | sodium arsenite | sodium arsenite promotes the reaction [CCND1 protein binds to CDK4 protein] | 21726611 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CDK4 mRNA | 20886546 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CDK4 protein | 26878773 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of CDK4 protein | 21726611 |
| C017947 | sodium arsenite | Plant Extracts inhibits the reaction [sodium arsenite results in decreased expression of CDK4 protein] | 27723467 |
| C017947 | sodium arsenite | sodium arsenite affects the expression of CDK4 mRNA | 16507464 |
| C017947 | sodium arsenite | sodium arsenite results in decreased activity of CDK4 protein | 11807808 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CDK4 protein | 20336670|2772346 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of CDK4 protein | 16507464 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CDK4 mRNA | 20598115|2196446 |
| C017947 | sodium arsenite | sodium arsenite results in decreased expression of CDK4 protein | 20598115|2196446 |
| C017947 | sodium arsenite | Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of CDK4 mRNA] | 21964460 |
| C016104 | sodium bichromate | sodium bichromate results in increased expression of CDK4 mRNA | 22561333 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of CDK4 mRNA | 16705456 |
| C471405 | sorafenib | [sorafenib co-treated with rottlerin] results in decreased expression of CDK4 protein | 16959960 |
| C471405 | sorafenib | sorafenib results in decreased expression of CDK4 protein | 16959960 |
| D013467 | Sulindac | CTNNB1 protein affects the reaction [Sulindac results in decreased expression of CDK4 protein] | 18291362 |
| D013467 | Sulindac | Sulindac results in decreased expression of CDK4 protein | 17292881|1829136 |
| D013467 | Sulindac | "[Sulindac co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of CDK4 mRNA" | 20371263 |
| C112765 | tanespimycin | tanespimycin results in decreased expression of CDK4 protein | 17157164|2867368 |
| C011363 | terephthalic acid | terephthalic acid results in increased expression of CDK4 protein | 16896691 |
| C534735 | tetraarsenic tetrasulfide | [Imatinib Mesylate co-treated with tetraarsenic tetrasulfide] results in decreased expression of CDK4 mRNA | 19208803 |
| C020806 | tetrabromobisphenol A | tetrabromobisphenol A affects the expression of CDK4 mRNA | 26988606 |
| D013749 | Tetrachlorodibenzodioxin | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CDK4 protein] | 27312872 |
| D013749 | Tetrachlorodibenzodioxin | AHR protein affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CDK4 protein] | 27312872 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [AHR protein binds to CDK4 protein] | 19917880 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [[AHR protein binds to CDK4 protein binds to CCND1 protein] which results in increased phosphorylation of RB1 protein] | 19917880 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased activity of CDK4 protein] | 9705214 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [Estradiol inhibits the reaction [CDK4 protein binds to CDKN1A protein]] | 9705214 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CDK4 protein | 27312872 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CDK4 protein | 9707505 |
| D013749 | Tetrachlorodibenzodioxin | "Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene promotes the reaction [CDK4 protein binds to CCND1 protein]]" | 20637255 |
| D013749 | Tetrachlorodibenzodioxin | "Tetrachlorodibenzodioxin promotes the reaction [1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased activity of CDK4 protein]" | 20637255 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of CDK4 mRNA | 19770486 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [CCND2 protein binds to CDK4 protein] | 12387751 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CDK4 mRNA | 16960034|2413658 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in decreased expression of CDK4 mRNA | 15978937 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of CDK4 protein | 24073338 |
| D013755 | Tetradecanoylphorbol Acetate | PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA] | 10866668 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA | 10866668 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CDK4 mRNA | 25613284 |
| D013849 | Thimerosal | Thimerosal results in decreased expression of CDK4 protein | 16649253 |
| D013853 | Thioacetamide | Thioacetamide results in decreased expression of CDK4 mRNA | 11793227 |
| C003440 | thioacridone | thioacridone results in decreased activity of CDK4 protein | 15724842 |
| D013881 | Thioridazine | Thioridazine results in decreased expression of CDK4 protein | 21035837 |
| C003466 | thymoquinone | thymoquinone inhibits the reaction [Diethylnitrosamine results in increased expression of CDK4 protein] | 24012840 |
| D024505 | Tocopherols | Tocopherols results in decreased expression of and results in decreased activity of CDK4 protein | 12504091 |
| D014118 | Toxins, Biological | "Toxins, Biological affects the expression of CDK4 mRNA" | 19682533 |
| C496197 | trans-10,cis-12-conjugated linoleic acid | "trans-10,cis-12-conjugated linoleic acid results in decreased expression of CDK4 mRNA" | 17951470 |
| D014212 | Tretinoin | Tretinoin results in increased activity of CDK4 protein | 15695403 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [FGF2 protein results in increased expression of CDK4 mRNA] | 11675954 |
| D014212 | Tretinoin | Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of CDK4 mRNA] | 21964460 |
| D014212 | Tretinoin | Tretinoin results in decreased expression of CDK4 protein | 11675954 |
| C447082 | tricarbonyldichlororuthenium (II) dimer | tricarbonyldichlororuthenium (II) dimer results in decreased expression of CDK4 protein | 24211270 |
| C012589 | trichostatin A | trichostatin A results in decreased expression of CDK4 mRNA | 19606018|2377000 |
| C015559 | trimellitic anhydride | trimellitic anhydride results in increased expression of CDK4 mRNA | 19042947 |
| C001899 | triptolide | triptolide results in increased expression of CDK4 protein | 26990902 |
| C080938 | tris(2-carboxyethyl)phosphine | tris(2-carboxyethyl)phosphine results in decreased expression of CDK4 protein | 18952254 |
| C057693 | troglitazone | GSK3B protein affects the susceptibility to [troglitazone results in decreased expression of CDK4 protein] | 20540935 |
| C057693 | troglitazone | "[N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea results in decreased activity of GSK3B protein] results in increased susceptibility to [troglitazone results in decreased expression of CDK4 protein]" | 20540935 |
| C057693 | troglitazone | troglitazone results in decreased expression of CDK4 mRNA | 19140230 |
| C057693 | troglitazone | troglitazone results in decreased expression of CDK4 protein | 20540935 |
| C057693 | troglitazone | troglitazone results in decreased expression of CDK4 protein | 15610522 |
| C046243 | tryptanthrine | tryptanthrine results in decreased expression of CDK4 protein | 23500671 |
| D014403 | Tubocurarine | Tubocurarine inhibits the reaction [Nicotine results in decreased expression of CDK4 protein] | 15231866 |
| C113580 | U 0126 | U 0126 results in decreased expression of CDK4 protein | 15930308 |
| C000602704 | UF010 compound | UF010 compound results in decreased activity of CDK4 protein | 25699604 |
| D014508 | Urea | Urea analog results in decreased activity of [CCND1 protein binds to CDK4 protein] | 10403840 |
| D014520 | Urethane | Urethane results in decreased expression of CDK4 mRNA | 28818685 |
| D014520 | Urethane | Urethane results in increased expression of CDK4 mRNA | 12117781 |
| D014520 | Urethane | Urethane results in increased expression of CDK4 protein | 12117781 |
| C005466 | ursolic acid | ursolic acid results in decreased expression of CDK4 protein | 24802810 |
| C073339 | usnic acid | usnic acid results in decreased expression of CDK4 protein | 27369375 |
| D014635 | Valproic Acid | [Hydralazine co-treated with Valproic Acid] results in increased expression of CDK4 mRNA | 17183730 |
| D014635 | Valproic Acid | Valproic Acid results in decreased expression of CDK4 mRNA | 29154799 |
| C551177 | vemurafenib | vemurafenib results in decreased expression of CDK4 protein | 27087167 |
| C017963 | vinyl carbamate | vinyl carbamate results in decreased expression of CDK4 mRNA | 17849452 |
| D014810 | Vitamin E | Vitamin E results in increased expression of CDK4 mRNA | 19244175 |
| C024534 | vitamin k5 | vitamin k5 results in decreased expression of CDK4 mRNA | 16010434 |
| D024482 | Vitamin K 2 | Vitamin K 2 results in decreased expression of CDK4 mRNA | 16010434 |
| D024483 | Vitamin K 3 | Vitamin K 3 results in decreased expression of CDK4 mRNA | 16010434 |
| C111237 | vorinostat | [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with vorinostat] results in decreased expression of CDK4 protein | 19440035 |
| C111237 | vorinostat | vorinostat results in decreased expression of CDK4 protein | 19440035 |
| C085514 | wogonin | wogonin results in decreased expression of CDK4 protein | 23872260 |
| C085514 | wogonin | wogonin results in decreased expression of CDK4 protein | 23872260 |
| C108830 | Y 27632 | Y 27632 results in decreased expression of CDK4 mRNA | 20578043 |
| D015029 | Zeranol | Zeranol results in decreased expression of CDK4 protein | 24120472 |
| D015215 | Zidovudine | [Zidovudine co-treated with IFNA1 protein] results in increased expression of CDK4 mRNA | 20370541 |
| C088658 | zoledronic acid | [zoledronic acid co-treated with Doxorubicin] results in decreased expression of CDK4 protein | 19789217 |