Gene: PATJ

10207
Cipp|INADL|InaD-like|hINADL
PATJ, crumbs cell polarity complex component
protein-coding
1p31.3
Ensembl:ENSG00000132849 MIM:603199 Vega:OTTHUMG00000008560 UniprotKB:Q8NI35
NC_000001.11
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.191e-1 (AD)  1.109e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10889272chr1:61936877 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
D000082AcetaminophenAcetaminophen results in decreased expression of PATJ mRNA21420995|2906747
D000082AcetaminophenAcetaminophen results in increased expression of PATJ mRNA22230336|2669055
D020106AcrylamideAcrylamide results in increased expression of PATJ mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of PATJ protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of PATJ mRNA22100608|2715375
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of PATJ gene27153756
D000393Air PollutantsAir Pollutants analog results in decreased expression of PATJ mRNA21757418
D000639AmitriptylineAmitriptyline results in decreased expression of PATJ mRNA22341215
D000643Ammonium ChlorideAmmonium Chloride affects the expression of PATJ mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents affects the expression of PATJ mRNA24449571
C547126AZM551248AZM551248 results in decreased expression of PATJ mRNA22323515
D001554BenzeneBenzene results in decreased expression of PATJ mRNA15120971|1512265
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PATJ mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of PATJ mRNA21715664
C006780bisphenol Abisphenol A affects the expression of PATJ mRNA25181051
C013418bromfenacoumbromfenacoum results in increased expression of PATJ protein28903499
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PATJ mRNA22079614
C018475butyraldehydebutyraldehyde results in decreased expression of PATJ mRNA26079696
D019256Cadmium ChlorideCadmium Chloride affects the expression of PATJ mRNA22110744
D002220CarbamazepineCarbamazepine affects the expression of PATJ mRNA25979313
D003375CoumestrolCoumestrol results in decreased expression of PATJ mRNA19167446
D003471CuprizoneCuprizone results in increased expression of PATJ mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of PATJ mRNA19770486
D013759DronabinolDronabinol results in decreased expression of PATJ mRNA21955143
D004041Dietary FatsDietary Fats results in decreased expression of PATJ mRNA25016146
D002117CalcitriolCalcitriol results in increased expression of PATJ mRNA26485663
C118739entinostatentinostat results in increased expression of PATJ mRNA27188386
D000431EthanolEthanol results in increased expression of PATJ mRNA21955143
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of PATJ mRNA28196854
D018120FinasterideFinasteride results in increased expression of PATJ mRNA24136188
D005485FlutamideFlutamide results in increased expression of PATJ mRNA24136188
D005557FormaldehydeFormaldehyde results in decreased expression of PATJ mRNA20655997|2364984
C040029gabapentin[gabapentin co-treated with Pentylenetetrazole] affects the expression of PATJ mRNA21503142
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of PATJ mRNA22634610
D017313FenretinideFenretinide results in increased expression of PATJ mRNA28973697
C042720mercuric bromidemercuric bromide results in increased expression of PATJ mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
D008627Mercuric ChlorideMercuric Chloride results in decreased expression of PATJ mRNA27188386
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of PATJ mRNA26011545
D008770MethylnitrosoureaMethylnitrosourea results in increased expression of PATJ mRNA15240709
D009020MorphineMorphine results in decreased expression of PATJ mRNA21955143
C523799MRK 003PATJ results in decreased susceptibility to MRK 00319903844
C500085muraglitazarmuraglitazar results in increased expression of PATJ mRNA21515302
D009151Mustard GasMustard Gas affects the expression of PATJ mRNA15651846
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of PATJ mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of PATJ mRNA"25554681
D009538NicotineNicotine results in decreased expression of PATJ mRNA21955143
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C046012pentanalpentanal results in decreased expression of PATJ mRNA26079696
D010433Pentylenetetrazole[gabapentin co-treated with Pentylenetetrazole] affects the expression of PATJ mRNA21503142
D010433Pentylenetetrazole[Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PATJ mRNA21503142
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of PATJ mRNA26272509
D011192Potassium DichromatePotassium Dichromate results in decreased expression of PATJ mRNA23608068
D011441PropylthiouracilPropylthiouracil results in decreased expression of PATJ mRNA24780913
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of PATJ mRNA25895662
D012906SmokeSmoke results in decreased expression of PATJ mRNA21095227
C009277sodium arsenatesodium arsenate results in increased expression of PATJ mRNA21795629
C016104sodium bichromatesodium bichromate affects the expression of PATJ mRNA22110744
C501413tesaglitazartesaglitazar results in increased expression of PATJ mRNA21515302
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of PATJ mRNA21570461|2637764
D014212TretinoinTretinoin results in increased expression of PATJ mRNA21934132
D014241TrichloroethyleneTrichloroethylene results in decreased expression of PATJ mRNA26745549
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of PATJ mRNA24935251|2627250
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of PATJ mRNA29024780
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PATJ mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of PATJ mRNA23179753|2438349
D020888Vigabatrin[Pentylenetetrazole co-treated with Vigabatrin] affects the expression of PATJ mRNA21503142
C025643vinclozolinvinclozolin results in decreased expression of PATJ mRNA23034163
C029297vinylidene chloridevinylidene chloride results in decreased expression of PATJ mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI11927608  12021270  18596123  21481793  24366813  
GO ID GO Term Qualifier Evidence PubMed
GO:0035556intracellular signal transduction-NAS9280290  
GO:0070830bicellular tight junction assembly-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005813centrosome-IDA-  
GO:0005815microtubule organizing center-IDA-  
GO:0005829cytosol-IDA-  
GO:0005886plasma membrane-TAS-  
GO:0005923bicellular tight junction-IDA22006950  
GO:0016324apical plasma membrane-IEA-  
GO:0030054cell junction-IDA-  
GO:0032991protein-containing complex-IEA-  
GO:0048471perinuclear region of cytoplasm-IDA18596123  
GO:0070062extracellular exosome-HDA19056867  23533145  
KEGG ID KEGG Term
hsa04530Tight junction
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal