| C093337 | 1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine | "1-(2-(3,4-dichlorophenyl)ethyl)-4-methylpiperazine binds to and results in decreased activity of SIGMAR1 protein" | 15451042 |
| C049325 | 1,2-dithiol-3-thione | "1,2-dithiol-3-thione results in increased expression of SIGMAR1 mRNA" | 19162173 |
| C404207 | 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone | "1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone binds to and results in increased activity of SIGMAR1 protein" | 11907181 |
| C404207 | 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone | "[1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone binds to and results in increased activity of SIGMAR1 protein] which results in increased secretion of Acetylcholine" | 11907181 |
| C404207 | 1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone | "[N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride binds to and results in decreased activity of SIGMAR1 protein] inhibits the reaction [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone results in increased secretion of Acetylcholine]" | 11907181 |
| C495626 | 14-deoxy-11,12-didehydroandrographolide | "14-deoxy-11,12-didehydroandrographolide results in decreased expression of SIGMAR1 mRNA" | 22101062 |
| C097775 | 1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine | "1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine inhibits the reaction [Pentazocine binds to SIGMAR1 protein]" | 21229979 |
| C051246 | 1-methylanthracene | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of SIGMAR1 mRNA | 28329830 |
| C107238 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine binds to and results in decreased activity of SIGMAR1 protein" | 20956312 |
| C107238 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]" | 20956312 |
| C107238 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]" | 20956312 |
| C107238 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]" | 20956312 |
| C107238 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]" | 20956312 |
| C111118 | 2',3,3',4',5-pentachloro-4-hydroxybiphenyl | "2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of SIGMAR1 mRNA" | 19114083 |
| C014024 | 2,4,5,2',4',5'-hexachlorobiphenyl | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of SIGMAR1 mRNA" | 28433925 |
| C071738 | 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate | [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine Hydrobromide | 12028363 |
| C071738 | 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate | 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein | 16012353|1817380 |
| C023035 | 3,4,5,3',4'-pentachlorobiphenyl | "3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SIGMAR1 mRNA" | 23196670 |
| C577636 | 3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide | 3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide binds to SIGMAR1 protein | 22923735 |
| C577635 | 5,6-dimethoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide | "5,6-dimethoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide binds to SIGMAR1 protein" | 22923735 |
| C577635 | 5,6-dimethoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide | "5,6-dimethoxy-3-methyl-N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamide results in increased expression of SIGMAR1 protein" | 22923735 |
| D000082 | Acetaminophen | [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA | 17585979 |
| D000082 | Acetaminophen | PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA] | 17585979 |
| D000109 | Acetylcholine | "[1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone binds to and results in increased activity of SIGMAR1 protein] which results in increased secretion of Acetylcholine" | 11907181 |
| D000109 | Acetylcholine | "[N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride binds to and results in decreased activity of SIGMAR1 protein] inhibits the reaction [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone results in increased secretion of Acetylcholine]" | 11907181 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 results in decreased expression of SIGMAR1 mRNA | 19770486 |
| C050408 | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol binds to and results in decreased activity of SIGMAR1 protein | 18281903|1928336 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of SIGMAR1 mRNA | 16483693 |
| C547126 | AZM551248 | AZM551248 results in increased expression of SIGMAR1 mRNA | 22323515 |
| C085527 | BD 1008 | BD 1008 analog binds to SIGMAR1 protein | 11164383 |
| C085527 | BD 1008 | BD 1008 binds to SIGMAR1 protein | 11164383 |
| C085527 | BD 1008 | BD 1008 analog binds to SIGMAR1 protein | 11426838 |
| C085527 | BD 1008 | BD 1008 analog binds to and results in decreased activity of SIGMAR1 protein | 11426838 |
| D001549 | Benzamides | Benzamides analog binds to SIGMAR1 protein | 9352539 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of SIGMAR1 mRNA | 20106945 |
| C013409 | benzoyl chloride | benzoyl chloride analog binds to SIGMAR1 protein | 9352539 |
| C006780 | bisphenol A | bisphenol A affects the expression of SIGMAR1 mRNA | 21786754 |
| C006780 | bisphenol A | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of SIGMAR1 mRNA" | 28433925 |
| C006780 | bisphenol A | bisphenol A results in increased expression of SIGMAR1 mRNA | 25181051 |
| D000069286 | Bortezomib | Bortezomib results in decreased expression of SIGMAR1 mRNA | 20977926 |
| D002110 | Caffeine | Caffeine results in decreased expression of SIGMAR1 mRNA | 20864626 |
| D020111 | Chlorodiphenyl (54% Chlorine) | Chlorodiphenyl (54% Chlorine) results in decreased expression of SIGMAR1 mRNA | 25270620 |
| D002994 | Clofibrate | [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA | 17585979 |
| D002994 | Clofibrate | PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA] | 17585979 |
| D002995 | Clofibric Acid | Clofibric Acid affects the expression of SIGMAR1 mRNA | 17602206 |
| D002995 | Clofibric Acid | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA | 17602206 |
| C018021 | cobaltous chloride | cobaltous chloride results in decreased expression of SIGMAR1 mRNA | 19320972|1937684 |
| D003042 | Cocaine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]" | 20956312 |
| D003042 | Cocaine | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]" | 20956312 |
| D003042 | Cocaine | Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein] | 20956312 |
| D003042 | Cocaine | Cocaine binds to SIGMAR1 protein | 20956312 |
| D003042 | Cocaine | [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein] | 20956312 |
| D003042 | Cocaine | Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein] | 20956312 |
| D003042 | Cocaine | Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein] | 20956312 |
| D003042 | Cocaine | Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein] | 20956312 |
| D003042 | Cocaine | SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]] | 20956312 |
| D003042 | Cocaine | SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] | 20956312 |
| D003042 | Cocaine | Cocaine binds to SIGMAR1 protein | 12128006 |
| D003042 | Cocaine | Cocaine results in increased activity of and results in increased localization of SIGMAR1 protein | 20354174 |
| D003042 | Cocaine | methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased localization of SIGMAR1 protein] | 20354174 |
| D003042 | Cocaine | SIGMAR1 gene mutant form results in decreased susceptibility to Cocaine | 11006959 |
| D003042 | Cocaine | SIGMAR1 mRNA results in increased susceptibility to Cocaine | 11426838 |
| D003042 | Cocaine | SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein] | 20354174 |
| D003042 | Cocaine | SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] | 20354174 |
| D003042 | Cocaine | SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] | 20354174 |
| D003042 | Cocaine | SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK8 protein] | 20354174 |
| D003042 | Cocaine | SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of RELA protein] | 20354174 |
| D003042 | Cocaine | Cocaine results in increased activity of SIGMAR1 protein | 16204638 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased expression of SIGMAR1 mRNA | 19549813 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of SIGMAR1 mRNA | 20106945|2556210 |
| D003687 | Dehydroepiandrosterone | Dehydroepiandrosterone binds to and results in increased activity of SIGMAR1 protein | 12736327|1613206 |
| D003907 | Dexamethasone | Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SIGMAR1 mRNA] | 27941970 |
| D003917 | Dextrorphan | Dextrorphan binds to SIGMAR1 protein | 10064839 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of SIGMAR1 mRNA | 17379624 |
| D002945 | Cisplatin | [Cisplatin co-treated with jinfukang] results in increased expression of SIGMAR1 mRNA | 27392435 |
| C036042 | dicyclohexyl phthalate | dicyclohexyl phthalate affects the expression of SIGMAR1 mRNA | 26924002 |
| D004041 | Dietary Fats | [Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SIGMAR1 mRNA | 28433925 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of SIGMAR1 mRNA | 18042831 |
| D019422 | Dietary Sucrose | [Dietary Fats co-treated with Dietary Sucrose] results in decreased expression of SIGMAR1 mRNA | 28433925 |
| D004051 | Diethylhexyl Phthalate | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of SIGMAR1 mRNA" | 28433925 |
| D004052 | Diethylnitrosamine | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA | 17602206 |
| C012621 | dimemorfan | dimemorfan binds to and results in increased activity of SIGMAR1 protein | 18173806 |
| C012621 | dimemorfan | dimemorfan binds to SIGMAR1 protein | 15723099 |
| C012621 | dimemorfan | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] | 15723099 |
| C012621 | dimemorfan | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]] | 15723099 |
| C012621 | dimemorfan | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]] | 15723099 |
| C012621 | dimemorfan | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] | 15723099 |
| C012621 | dimemorfan | dimemorfan binds to and results in increased activity of SIGMAR1 protein | 15081388|1850035 |
| C012621 | dimemorfan | dimemorfan binds to SIGMAR1 protein | 10064839 |
| C024629 | dimethyl phthalate | dimethyl phthalate affects the expression of SIGMAR1 mRNA | 26924002 |
| D004147 | Dioxins | Dioxins affects the expression of SIGMAR1 mRNA | 20463971 |
| D004298 | Dopamine | "[N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin results in decreased activity of SIGMAR1 protein] inhibits the reaction [NPY protein results in increased abundance of Dopamine]" | 18005069 |
| D004298 | Dopamine | SIGMAR1 protein promotes the reaction [NPY protein results in increased abundance of Dopamine] | 18005069 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of SIGMAR1 protein | 17631546 |
| D004785 | Environmental Pollutants | Environmental Pollutants results in increased expression of SIGMAR1 mRNA | 20064776 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol affects the expression of SIGMAR1 mRNA | 17555576 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of SIGMAR1 mRNA | 17942748 |
| D004997 | Ethinyl Estradiol | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIGMAR1 mRNA | 17942748 |
| D005419 | Flavonoids | Flavonoids results in increased expression of SIGMAR1 mRNA | 18035473 |
| C007738 | fluoranthene | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of SIGMAR1 mRNA | 28329830 |
| D005485 | Flutamide | Flutamide results in decreased expression of SIGMAR1 mRNA | 24793618 |
| D016666 | Fluvoxamine | Fluvoxamine binds to and results in increased activity of SIGMAR1 protein | 20148109 |
| D006220 | Haloperidol | Haloperidol binds to and results in decreased activity of SIGMAR1 protein | 15081388 |
| D017313 | Fenretinide | Fenretinide results in decreased expression of SIGMAR1 mRNA | 28973697 |
| C065310 | igmesine | [igmesine binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine Hydrobromide | 12028363 |
| C065310 | igmesine | igmesine binds to and results in increased activity of SIGMAR1 protein | 12736327|1545104 |
| D007213 | Indomethacin | Indomethacin results in increased expression of SIGMAR1 mRNA | 28201806 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SIGMAR1 mRNA | 25613284 |
| C544151 | jinfukang | [Cisplatin co-treated with jinfukang] results in increased expression of SIGMAR1 mRNA | 27392435 |
| C544151 | jinfukang | jinfukang results in increased expression of SIGMAR1 mRNA | 27392435 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]] | 15723099 |
| D007608 | Kainic Acid | SIGMAR1 protein affects the reaction [dimemorfan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] | 15723099 |
| C025340 | manganese chloride | manganese chloride results in increased expression of SIGMAR1 protein | 25732873 |
| D008627 | Mercuric Chloride | Mercuric Chloride affects the expression of SIGMAR1 mRNA | 20353558 |
| D003915 | Dextromethorphan | Dextromethorphan binds to SIGMAR1 protein | 15723099 |
| D003915 | Dextromethorphan | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]] | 15723099 |
| D003915 | Dextromethorphan | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of FOS protein]] | 15723099 |
| D003915 | Dextromethorphan | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN mRNA]] | 15723099 |
| D003915 | Dextromethorphan | SIGMAR1 protein affects the reaction [Dextromethorphan inhibits the reaction [Kainic Acid results in increased expression of JUN protein]] | 15723099 |
| D003915 | Dextromethorphan | Dextromethorphan binds to and results in increased activity of SIGMAR1 protein | 18500357 |
| D003915 | Dextromethorphan | Dextromethorphan binds to SIGMAR1 protein | 10064839 |
| D008727 | Methotrexate | Methotrexate affects the expression of SIGMAR1 mRNA | 18502557 |
| C108732 | methyl-beta-cyclodextrin | methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased localization of SIGMAR1 protein] | 20354174 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in increased expression of SIGMAR1 mRNA | 23103053 |
| C517284 | monomethyl phthalate | monomethyl phthalate affects the expression of SIGMAR1 mRNA | 26924002 |
| C568376 | MT19c compound | MT19c compound results in decreased expression of SIGMAR1 mRNA | 21781307 |
| C583365 | N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide | "N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of SIGMAR1 mRNA" | 29244179 |
| C097963 | N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin | "N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin binds to and results in decreased activity of SIGMAR1 protein" | 11006959|1514064 |
| C097963 | N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin | "N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin results in decreased activity of SIGMAR1 protein" | 18005069 |
| C097963 | N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin | "[N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin results in decreased activity of SIGMAR1 protein] inhibits the reaction [NPY protein results in decreased susceptibility to Pilocarpine]" | 18005069 |
| C097963 | N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin | "[N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin results in decreased activity of SIGMAR1 protein] inhibits the reaction [NPY protein results in increased abundance of Dopamine]" | 18005069 |
| C515439 | N-(2-(m-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine | N-(2-(m-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine binds to SIGMAR1 protein | 16797004 |
| C515440 | N-(2-(o-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine | N-(2-(o-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine binds to SIGMAR1 protein | 16797004 |
| C515441 | N-(2-(p-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine | N-(2-(p-methoxyphenyl)ethyl)-N-ethyl-2-(1-pyrrolidinyl)ethylamine binds to SIGMAR1 protein | 16797004 |
| D009270 | Naloxone | Naloxone binds to SIGMAR1 protein | 3744788 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon analog results in decreased expression of SIGMAR1 mRNA" | 25620056 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in decreased expression of SIGMAR1 mRNA" | 25620056 |
| D037742 | Nanotubes, Carbon | "Nanotubes, Carbon results in increased expression of SIGMAR1 mRNA" | 25554681 |
| C083832 | N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | "[N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride binds to and results in decreased activity of SIGMAR1 protein] inhibits the reaction [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone results in increased secretion of Acetylcholine]" | 11907181 |
| C083832 | N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride | "N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride binds to and results in decreased activity of SIGMAR1 protein" | 11006959|1601235 |
| D019319 | Okadaic Acid | Okadaic Acid results in increased expression of SIGMAR1 protein | 26732598 |
| C009618 | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | "O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate results in decreased expression of SIGMAR1 mRNA" | 21673326 |
| D010100 | Oxygen | Oxygen deficiency results in decreased expression of SIGMAR1 mRNA | 26516004 |
| D017239 | Paclitaxel | Paclitaxel analog results in increased expression of SIGMAR1 mRNA | 15585946 |
| D000073878 | Palm Oil | Palm Oil results in decreased expression of SIGMAR1 mRNA | 18042831 |
| C103849 | panamesine | panamesine binds to SIGMAR1 protein | 10817525 |
| C513937 | PB28 compound | PB28 compound inhibits the reaction [Pentazocine binds to SIGMAR1 protein] | 21229979 |
| D010423 | Pentazocine | "1-cyclohexyl-4-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl)piperazine inhibits the reaction [Pentazocine binds to SIGMAR1 protein]" | 21229979 |
| D010423 | Pentazocine | PB28 compound inhibits the reaction [Pentazocine binds to SIGMAR1 protein] | 21229979 |
| D010423 | Pentazocine | Pentazocine binds to SIGMAR1 protein | 21229979 |
| D010423 | Pentazocine | Pentazocine binds to SIGMAR1 protein | 9352539 |
| D010423 | Pentazocine | Pentazocine binds to and results in increased activity of SIGMAR1 protein | 3744788 |
| D010423 | Pentazocine | Pentazocine binds to SIGMAR1 protein | 15046867 |
| C076994 | perfluorooctane sulfonic acid | perfluorooctane sulfonic acid results in increased expression of SIGMAR1 mRNA | 18692542 |
| D010634 | Phenobarbital | Phenobarbital affects the expression of SIGMAR1 mRNA | 23091169 |
| D010862 | Pilocarpine | "[N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin results in decreased activity of SIGMAR1 protein] inhibits the reaction [NPY protein results in decreased susceptibility to Pilocarpine]" | 18005069 |
| D010879 | Piperazines | Piperazines binds to SIGMAR1 protein | 15099923 |
| D010880 | Piperidines | Piperidines analog binds to SIGMAR1 protein | 9352539 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of SIGMAR1 mRNA | 18445702 |
| C006253 | pirinixic acid | pirinixic acid results in increased expression of SIGMAR1 mRNA | 15302862|1830175 |
| C006253 | pirinixic acid | PPARA protein promotes the reaction [pirinixic acid results in increased expression of SIGMAR1 mRNA] | 20059764 |
| D011284 | Pregnenolone | SIGMAR1 protein results in increased abundance of Pregnenolone | 22923735 |
| D011284 | Pregnenolone | Pregnenolone binds to and results in increased activity of SIGMAR1 protein | 12736327|1613206 |
| D011285 | Pregnenolone Carbonitrile | Pregnenolone Carbonitrile affects the expression of SIGMAR1 mRNA | 19162173 |
| D011374 | Progesterone | Progesterone binds to and results in decreased activity of SIGMAR1 protein | 12736327|1613206 |
| D020849 | Raloxifene Hydrochloride | Raloxifene Hydrochloride binds to SIGMAR1 protein | 16033255 |
| C059514 | resveratrol | resveratrol results in increased expression of SIGMAR1 protein | 25505154 |
| C034931 | rimcazole | rimcazole binds to and results in decreased activity of SIGMAR1 protein | 12801223 |
| C034931 | rimcazole | rimcazole binds to SIGMAR1 protein | 11684152 |
| C101789 | SA 4503 | SA 4503 binds to SIGMAR1 protein | 17631546 |
| C101789 | SA 4503 | SA 4503 binds to and results in increased activity of SIGMAR1 protein | 12409992 |
| C534628 | SCH 23390 | SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]] | 20956312 |
| C534628 | SCH 23390 | SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] | 20956312 |
| C534628 | SCH 23390 | SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]] | 20956312 |
| C534628 | SCH 23390 | SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] | 20956312 |
| D012601 | Scopolamine Hydrobromide | [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine Hydrobromide | 12028363 |
| D012601 | Scopolamine Hydrobromide | [igmesine binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine Hydrobromide | 12028363 |
| C012134 | SK&F 10047 | SK&F 10047 binds to and results in increased activity of SIGMAR1 protein | 15081388 |
| C012134 | SK&F 10047 | SK&F 10047 results in increased activity of SIGMAR1 protein | 17460149 |
| C067113 | SK&F 81297 | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]" | 20956312 |
| C067113 | SK&F 81297 | "1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]" | 20956312 |
| C067113 | SK&F 81297 | SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]] | 20956312 |
| C067113 | SK&F 81297 | SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] | 20956312 |
| C067113 | SK&F 81297 | SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein] | 20956312 |
| C067113 | SK&F 81297 | SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein] | 20956312 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of SIGMAR1 mRNA | 15953391 |
| D013629 | Tamoxifen | Tamoxifen affects the expression of SIGMAR1 mRNA | 17555576 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | "[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in decreased expression of SIGMAR1 mRNA" | 28433925 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIGMAR1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of SIGMAR1 mRNA | 25975270 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to SIGMAR1 gene] | 28213091 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in decreased expression of SIGMAR1 mRNA | 28213091 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of SIGMAR1 mRNA | 17942748 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA | 22298810 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SIGMAR1 mRNA | 25613284 |
| C423915 | TO-901317 | TO-901317 results in increased expression of SIGMAR1 mRNA | 15302862 |
| D014028 | Tobacco Smoke Pollution | Tobacco Smoke Pollution results in decreased expression of SIGMAR1 mRNA | 28065790 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SIGMAR1 mRNA | 15901671 |
| C012589 | trichostatin A | trichostatin A results in increased expression of SIGMAR1 mRNA | 15901671 |
| C016805 | tris(1,3-dichloro-2-propyl)phosphate | "tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of SIGMAR1 mRNA" | 26179874 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SIGMAR1 mRNA | 15901671 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of SIGMAR1 mRNA | 25979313 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of SIGMAR1 gene | 29154799 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SIGMAR1 mRNA | 23179753 |
| D014635 | Valproic Acid | Valproic Acid affects the expression of SIGMAR1 mRNA | 17292431 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of SIGMAR1 mRNA | 15901671 |
| C025643 | vinclozolin | vinclozolin results in decreased expression of SIGMAR1 mRNA | 23555832 |
| C025643 | vinclozolin | vinclozolin results in increased expression of SIGMAR1 mRNA | 22570695 |