Gene: SPON1

10418
VSGP/F-spondin|f-spondin
spondin 1
protein-coding
11p15.2
Ensembl:ENSG00000262655 MIM:604989 Vega:OTTHUMG00000181576 UniprotKB:Q9HCB6
NC_000011.10
PubMed|SNP Mapped
OD|AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.955e-1 (AD)  1.515e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2303975chr11:14255453 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs731274chr11:14252131 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs12575169chr11:13976261 (GRCh38.p7)A>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NTRK20.936
ATP13A40.922
GJA10.921
GPAM0.921
ELOVL20.921
SLC4A40.917
EGFR0.916
METTL7A0.913
GABRG10.912
SOX90.908

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TC2N-0.363
MCHR1-0.354
DUSP27-0.354
SULT2B1-0.35
CACNA1F-0.349
QRFPR-0.348
CD163L1-0.347
GALNTL5-0.347
LGI2-0.343
SCARA5-0.343

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0067181,12-benzoperylene"1,12-benzoperylene results in increased expression of SPON1 mRNA"26377693
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of SPON1 mRNA"26377693
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of SPON1 mRNA"19114083
C0131862,3-pentanedione"2,3-pentanedione results in increased expression of SPON1 mRNA"25710175
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SPON1 mRNA"23196670
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C0238294-nitroso-N-phenylanilineSPON1 gene SNP affects the susceptibility to 4-nitroso-N-phenylaniline25622337
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of SPON1 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of SPON1 gene28458013
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of SPON1 mRNA23630614
D006710HomocysteineHomocysteine results in decreased expression of SPON1 mRNA17326132
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SPON1 mRNA16483693
C006632arsenic trioxidearsenic trioxide results in decreased expression of SPON1 mRNA26705709
D001280AtrazineAtrazine results in decreased expression of SPON1 mRNA25929836
D001379AzathioprineAzathioprine results in increased expression of SPON1 mRNA19192274
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of SPON1 mRNA26377693
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPON1 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of SPON1 mRNA19770486|2261060
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of SPON1 mRNA17404688
D004958EstradiolEstradiol results in increased expression of SPON1 mRNA19484750
C006780bisphenol Abisphenol A results in decreased methylation of SPON1 promoter27312807
C006780bisphenol Abisphenol A results in increased expression of SPON1 mRNA26063408
C006780bisphenol Abisphenol A results in decreased expression of SPON1 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of SPON1 gene28505145
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SPON1 mRNA20147733
D002101Cacodylic AcidCacodylic Acid results in decreased expression of SPON1 mRNA16122865
D007631ChlordeconeSPON1 gene SNP affects the susceptibility to Chlordecone25622337
D002713Chlorine[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA18636392
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in decreased expression of SPON1 mRNA26272509
C023676chloroquine diphosphatechloroquine diphosphate results in increased expression of SPON1 mRNA19192274
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of SPON120938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPON1 gene20938992
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPON1 mRNA20938992
D003078ColchicineColchicine results in increased expression of SPON1 mRNA20624997
C408982CPG-oligonucleotideCPG-oligonucleotide results in increased expression of SPON1 protein17727805
D003561CytarabineCytarabine results in decreased expression of SPON1 mRNA21198554
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SPON1 mRNA28628672
D003907DexamethasoneDexamethasone results in decreased expression of SPON1 mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of SPON1 mRNA]20032058
D002945CisplatinSPON1 protein affects the susceptibility to Cisplatin16217747
D004041Dietary FatsDietary Fats results in increased expression of SPON1 mRNA18042831
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPON1 mRNA18164116
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of SPON1 mRNA17005392
D004237DiuronDiuron results in decreased expression of SPON1 mRNA25152437
D004317DoxorubicinDoxorubicin affects the expression of SPON1 mRNA15205334
C118739entinostatentinostat results in decreased expression of SPON1 mRNA26272509
C118739entinostatentinostat results in increased expression of SPON1 mRNA27188386
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of SPON1 mRNA17942748
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of SPON1 mRNA12655037|1583489
D005419FlavonoidsFlavonoids results in increased expression of SPON1 mRNA18035473
D005472FluorouracilFluorouracil affects the expression of SPON1 mRNA15205334
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of SPON120938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPON1 gene20938992
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPON1 mRNA20938992
C039281furanfuran results in increased expression of SPON1 mRNA27387713
D006052Gold Sodium ThiomalateGold Sodium Thiomalate results in increased expression of SPON1 mRNA19192274
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SPON1 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of SPON1 mRNA28628672
D008070LipopolysaccharidesLipopolysaccharides results in decreased expression of SPON1 mRNA22235868
C042720mercuric bromidemercuric bromide results in decreased expression of SPON1 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of SPON120938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SPON1 gene20938992
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SPON1 mRNA20938992
D008727MethotrexateMethotrexate results in increased expression of SPON1 mRNA19192274
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of SPON1 mRNA28001369
D015735MifepristoneMifepristone results in decreased expression of SPON1 mRNA25972201
D008942MitoxantroneSPON1 protein affects the susceptibility to Mitoxantrone16217747
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of SPON1 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of SPON1 mRNA"25554681
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPON1 mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of SPON1 mRNA27935865
C025589ochratoxin Aochratoxin A results in decreased methylation of SPON1 gene26431795
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of SPON1 mRNA25729387
D010126Ozone[Ozone co-treated with Chlorine] affects the expression of SPON1 mRNA18636392
D000073878Palm OilPalm Oil results in increased expression of SPON1 mRNA18042831
D052638Particulate Matter[SPON1 gene mutant form affects the susceptibility to Particulate Matter] which results in decreased expression of SPON1 mRNA21222557|2122255
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of SPON1 mRNA"25510870
D010634PhenobarbitalPhenobarbital results in increased expression of SPON1 mRNA12082028
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of SPON1 mRNA26272509
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPON1 mRNA27935865
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of SPON1 mRNA19710929
C006253pirinixic acidpirinixic acid results in increased expression of SPON1 mRNA12832660
D011192Potassium DichromatePotassium Dichromate results in increased expression of SPON1 mRNA23608068
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of SPON1 mRNA17404688
D011441PropylthiouracilPropylthiouracil results in decreased expression of SPON1 mRNA24780913
C017947sodium arsenitesodium arsenite affects the methylation of SPON1 gene28589171
D053260SootSoot affects the expression of SPON1 mRNA26551751
D053260SootSoot results in increased expression of SPON1 mRNA22461453
D013629TamoxifenTamoxifen results in increased expression of SPON1 mRNA25123088
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in decreased expression of SPON1 mRNA]20032058
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SPON1 mRNA26377647
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SPON1 mRNA27913140
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SPON1 mRNA19770486|2527062
C009495titanium dioxidetitanium dioxide results in increased expression of SPON1 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of SPON1 mRNA25729387
D019772TopotecanTopotecan results in increased expression of SPON1 mRNA25729387
D014212TretinoinTretinoin results in increased expression of SPON1 mRNA21934132
C032910triadimefontriadimefon results in increased expression of SPON1 mRNA26705709
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
C012589trichostatin Atrichostatin A results in decreased expression of SPON1 mRNA26272509
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SPON1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of SPON1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of SPON1 mRNA24383497|2627250
D014635Valproic AcidValproic Acid results in increased methylation of SPON1 gene29154799
D014640VancomycinVancomycin results in decreased expression of SPON1 mRNA18930951
D001335Vehicle Emissions[SPON1 gene mutant form affects the susceptibility to Vehicle Emissions] which results in decreased expression of SPON1 mRNA21222557|2122255
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SPON1 gene25560391
D014747VinblastineVinblastine results in increased expression of SPON1 mRNA20624997
C025643vinclozolinvinclozolin results in increased expression of SPON1 mRNA20566332
D014750VincristineVincristine results in increased expression of SPON1 mRNA20624997
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of SPON1 mRNA27935865
D015032ZincZinc results in decreased expression of SPON1 mRNA18316168

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI14983046  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-HDA20551380  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
GO:0062023collagen-containing extracellular matrixcolocalizes_withISS22261194  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-1643685DiseaseTAS
R-HSA-3781865Diseases of glycosylationTAS
R-HSA-3906995Diseases associated with O-glycosylation of proteinsTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-5083635Defective B3GALTL causes Peters-plus syndrome (PpS)TAS
R-HSA-5173105O-linked glycosylationTAS
R-HSA-5173214O-glycosylation of TSR domain-containing proteinsTAS
R-HSA-597592Post-translational protein modificationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27010727Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients. (2016 Mar)Yang HCPLoS Genet