Gene: CFDP1

10428
BCNT|BUCENTAUR|CENP-29|CP27|SWC5|Yeti|p97
craniofacial development protein 1
protein-coding
16q23.1
Ensembl:ENSG00000153774 MIM:608108 Vega:OTTHUMG00000137615 UniprotKB:Q9UEE9
NC_000016.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
9.490e-1 (AD)  1.672e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg03011941chr16:75468318CFDP1Promoter5.494e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PSMB60.916
CLTA0.916
ERP290.915
AIP0.912
MEA10.912
SOD10.911
DYNLRB10.91
PPIA0.91
DYNLL10.91
PHB0.909

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.734
OR4F29-0.724
P2RY14-0.263
FREM2-0.251
IL18RAP-0.251
ZIC5-0.251
SLC2A4-0.249
CC2D2B-0.248
VNN3-0.247
KCNK5-0.244

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CFDP1 mRNA"19114083
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFDP1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFDP1 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of CFDP1 mRNA26690555
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of CFDP1 mRNA24449571
D001280AtrazineAtrazine results in increased expression of CFDP1 mRNA22378314
D019324beta-Naphthoflavone[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFDP1 mRNA18164116
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CFDP1 mRNA21632981
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CFDP1 mRNA22228805
C006780bisphenol Abisphenol A results in increased expression of CFDP1 mRNA25181051
C013418bromfenacoumbromfenacoum results in decreased expression of CFDP1 protein28903499
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of CFDP1 mRNA23650126
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CFDP1 gene20938992
D019327Copper SulfateCopper Sulfate results in decreased expression of CFDP1 mRNA19549813
C014347decitabinedecitabine affects the expression of CFDP1 mRNA23300844
D003976DiazinonDiazinon affects the expression of CFDP1 mRNA22546817
D002945CisplatinCisplatin affects the expression of CFDP1 mRNA23300844
C000944dicrotophosdicrotophos results in decreased expression of CFDP1 mRNA28302478
D004026DieldrinDieldrin affects the expression of CFDP1 mRNA22546817
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFDP1 mRNA18164116
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of CFDP1 mRNA17555576
D018120FinasterideFinasteride results in increased expression of CFDP1 mRNA24136188
D005485FlutamideFlutamide results in decreased expression of CFDP1 mRNA24793618
D005485FlutamideFlutamide results in increased expression of CFDP1 mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CFDP1 gene20938992
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of CFDP1 mRNA22634610
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CFDP1 gene20938992
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CFDP1 mRNA28001369
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of CFDP1 mRNA25729387
D010416PentachlorophenolPentachlorophenol results in increased expression of CFDP1 mRNA23892564
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CFDP1 mRNA22714537
D012402RotenoneRotenone results in decreased expression of CFDP1 mRNA19013527
D013629TamoxifenTamoxifen affects the expression of CFDP1 mRNA17555576
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CFDP1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of CFDP1 mRNA16214954
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CFDP1 mRNA15328365|1661135
C009495titanium dioxidetitanium dioxide results in increased expression of CFDP1 mRNA23131501
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of CFDP1 mRNA25729387
D014241TrichloroethyleneTrichloroethylene results in increased expression of CFDP1 mRNA26745549
C012589trichostatin Atrichostatin A results in increased expression of CFDP1 mRNA24935251
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFDP1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of CFDP1 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CFDP1 mRNA26272509
D014638VanadatesVanadates results in increased expression of CFDP1 mRNA22714537

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003674molecular_function-ND-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007155cell adhesion-IEA-  
GO:0007275multicellular organism development-IEA-  
GO:0008150biological_process-ND-  
GO:0008360regulation of cell shape-IEA-  
GO:0042127regulation of cell proliferation-IEA-  
GO:2000270negative regulation of fibroblast apoptotic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000777condensed chromosome kinetochore-IEA-  
GO:0005575cellular_component-ND-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
29455858A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (2018 Mar 1)Sung YJAm J Hum Genet