Gene: CEBPG

1054
GPE1BP|IG/EBP-1
CCAAT enhancer binding protein gamma
protein-coding
19q13.11
Ensembl:ENSG00000153879 MIM:138972 Vega:OTTHUMG00000180469 UniprotKB:P53567
NC_000019.10
PubMed
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.526e-1 (AD)  4.229e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TARS0.871
C16orf720.861
DNAJB60.858
SIAH20.852
ALG20.851
CCT40.851
NUFIP20.85
CACYBP0.849
STIP10.849
PTGES30.849

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.613
OR4F29-0.575
SNX22-0.295
HES5-0.279
PDE11A-0.275
C5orf64-0.268
TNFRSF13B-0.259
MYLK2-0.257
TRPV5-0.254
TCL1A-0.246

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0512461-methylanthracene[1-methylanthracene co-treated with fluoranthene] results in increased expression of CEBPG mRNA28329830
C0326681-nitropyrene1-nitropyrene results in increased expression of CEBPG mRNA19041380
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in increased expression of CEBPG mRNA"25614096
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether analog results in increased expression of CEBPG mRNA"19095052
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CEBPG mRNA"19114083
C0212962-ethoxyethanol2-ethoxyethanol results in increased expression of CEBPG mRNA19643169
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]"17316017
C0415253,3',4,5'-tetrahydroxystilbene"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]"17316017
C517041(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)"(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II) results in increased expression of CEBPG mRNA"19561079
D000082AcetaminophenAcetaminophen results in increased expression of CEBPG mRNA21420995|2906747
C103505AM 251AM 251 results in increased expression of CEBPG mRNA16500647
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CEBPG mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of CEBPG mRNA24449571
C520888arachidin-1arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]17316017
C520888arachidin-1arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]17316017
D001151ArsenicArsenic affects the methylation of CEBPG gene25304211
D017638Asbestos, Crocidolite"Asbestos, Crocidolite affects the expression of CEBPG mRNA"25757056
D016589AstemizoleAstemizole results in decreased expression of CEBPG mRNA20221588
C006680baicaleinbaicalein results in decreased expression of CEBPG mRNA24560969
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CEBPG mRNA20106945|2163298
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CEBPG mRNA21569818
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CEBPG mRNA"20382639
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CEBPG mRNA"19150397
D004958EstradiolEGF protein promotes the reaction [Estradiol results in increased expression of CEBPG mRNA]24758408
D004958EstradiolEstradiol results in increased expression of CEBPG mRNA24758408
D004958EstradiolEstradiol results in increased expression of CEBPG mRNA20068009
C044887beta-methylcholinebeta-methylcholine affects the expression of CEBPG mRNA21179406
C095105bexarotenebexarotene results in decreased expression of CEBPG mRNA17178900
C006780bisphenol Abisphenol A affects the expression of CEBPG mRNA21786754
C006780bisphenol Abisphenol A results in decreased expression of CEBPG mRNA22194820
C006780bisphenol Abisphenol A results in decreased expression of CEBPG mRNA20678512
C006780bisphenol Abisphenol A results in increased expression of CEBPG mRNA29275510
C006780bisphenol Abisphenol A affects the methylation of CEBPG promoter27334623
C006780bisphenol Abisphenol A results in increased expression of CEBPG mRNA25181051
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of CEBPG mRNA22079614
D002101Cacodylic AcidCacodylic Acid results in decreased expression of CEBPG mRNA17720352
D002392CatechinCatechin results in increased expression of CEBPG mRNA15465739
C100187chloropicrinchloropicrin affects the expression of CEBPG mRNA26352163
C018021cobaltous chloridecobaltous chloride results in increased expression of CEBPG mRNA19376846
D003300Copper[NSC 689534 binds to Copper] which results in increased expression of CEBPG mRNA20971185
D019327Copper SulfateCopper Sulfate results in increased expression of CEBPG mRNA19549813
C408982CPG-oligonucleotideCPG-oligonucleotide results in decreased expression of CEBPG mRNA21878529
C030973cupric oxidecupric oxide results in increased expression of CEBPG mRNA22077320
D003471CuprizoneCuprizone results in increased expression of CEBPG mRNA27523638
D016572CyclosporineCyclosporine results in increased expression of CEBPG mRNA20106945|2163298
D013759DronabinolDronabinol results in increased expression of CEBPG mRNA16616335
C016366dibenzothiophenedibenzothiophene results in increased expression of CEBPG mRNA23656968
D002945CisplatinCisplatin promotes the reaction [Piroxicam results in decreased expression of CEBPG mRNA]21858171
D002945CisplatinCisplatin results in increased expression of CEBPG mRNA27594783
D004121Dimethyl SulfoxideDimethyl Sulfoxide results in decreased expression of CEBPG mRNA22169935
D004147DioxinsDioxins affects the expression of CEBPG mRNA20463971
D004221DisulfiramDisulfiram results in increased expression of CEBPG mRNA20530235
D004237DiuronDiuron results in increased expression of CEBPG mRNA21551480
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CEBPG mRNA17557909
D005419FlavonoidsFlavonoids results in decreased expression of CEBPG mRNA15465739
D005419FlavonoidsFlavonoids results in increased expression of CEBPG mRNA18035473
C007738fluoranthene[1-methylanthracene co-treated with fluoranthene] results in increased expression of CEBPG mRNA28329830
C061365flusilazoleflusilazole affects the expression of CEBPG mRNA21195148
C409722hexaconazolehexaconazole affects the expression of CEBPG mRNA21195148
D017313FenretinideFenretinide results in decreased expression of CEBPG mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CEBPG mRNA20044591
C492448ICG 001ICG 001 results in increased expression of CEBPG mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CEBPG mRNA25613284
D007545IsoproterenolIsoproterenol results in increased expression of CEBPG mRNA20003209
C410337K 7174K 7174 results in increased expression of CEBPG mRNA24086573
C045463leflunomideleflunomide results in increased expression of CEBPG mRNA28988120
D008070Lipopolysaccharides"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]"17316017
D008070Lipopolysaccharides"3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]"17316017
D008070Lipopolysaccharidesarachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]17316017
D008070Lipopolysaccharidesarachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]17316017
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CEBPG mRNA17316017
D008070LipopolysaccharidesLipopolysaccharides results in increased expression of CEBPG protein17316017
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]17316017
D008070Lipopolysaccharidesresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]17316017
D008627Mercuric ChlorideMercuric Chloride affects the expression of CEBPG mRNA20353558
C005219methyl cellosolvemethyl cellosolve results in increased expression of CEBPG mRNA19643169
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CEBPG mRNA23458150
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of CEBPG mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of CEBPG mRNA23649840
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in increased expression of CEBPG mRNA24810058
D016685MitomycinMitomycin results in decreased expression of CEBPG mRNA25270620
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of CEBPG mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CEBPG mRNA"25554681
C022838nickel chloridenickel chloride results in increased expression of CEBPG mRNA17312168
C570897NSC668394NSC668394 results in increased expression of CEBPG mRNA27137931
C558013NSC 689534[NSC 689534 binds to Copper] which results in increased expression of CEBPG mRNA20971185
C025589ochratoxin Aochratoxin A results in increased expression of CEBPG mRNA23358140
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of CEBPG mRNA18593933
C086401pentabromodiphenyl etherpentabromodiphenyl ether analog results in increased expression of CEBPG mRNA19095052
C086401pentabromodiphenyl etherpentabromodiphenyl ether results in increased expression of CEBPG mRNA26705709
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of CEBPG mRNA19162173
D010634PhenobarbitalPhenobarbital affects the expression of CEBPG mRNA19159669
D010634PhenobarbitalPhenobarbital affects the expression of CEBPG mRNA23091169
C006253pirinixic acidpirinixic acid results in increased expression of CEBPG mRNA19162173
D010894PiroxicamCisplatin promotes the reaction [Piroxicam results in decreased expression of CEBPG mRNA]21858171
D010894PiroxicamPiroxicam results in increased expression of CEBPG mRNA21858171
D010936Plant ExtractsPlant Extracts results in decreased expression of CEBPG mRNA15465739
D059808PolyphenolsPolyphenols results in decreased expression of CEBPG mRNA15465739
D011374ProgesteroneProgesterone results in increased expression of CEBPG mRNA18037150
C031280pyrazolepyrazole results in increased expression of CEBPG mRNA17945193
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]17316017
C059514resveratrolresveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]17316017
D012834SilverSilver results in decreased expression of CEBPG mRNA27131904
C017947sodium arsenitesodium arsenite results in decreased expression of CEBPG mRNA28595984
D018038Sodium SeleniteSodium Selenite results in increased expression of CEBPG mRNA18175754
D053260SootSoot results in increased expression of CEBPG mRNA26551751
C061133tamibarotenetamibarotene results in decreased expression of CEBPG mRNA15498508
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CEBPG mRNA18336851
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CEBPG mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CEBPG mRNA21570461
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of CEBPG mRNA21215274
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CEBPG mRNA25613284
D019284ThapsigarginThapsigargin results in increased expression of CEBPG mRNA22378314
D014212TretinoinTretinoin results in decreased expression of CEBPG mRNA15498508|1721838
C032910triadimefontriadimefon affects the expression of CEBPG mRNA21195148
C012589trichostatin Atrichostatin A results in increased expression of CEBPG mRNA15901671
C057693troglitazonetroglitazone results in increased expression of CEBPG mRNA24559133
D014415TunicamycinTunicamycin results in increased expression of CEBPG mRNA22378314
D017974Uranium CompoundsUranium Compounds results in decreased expression of CEBPG mRNA19654044
D014635Valproic AcidValproic Acid affects the expression of CEBPG mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CEBPG mRNA15901671
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of CEBPG gene25560391
C111237vorinostatvorinostat results in decreased expression of CEBPG mRNA22083351
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of CEBPG mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000978RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISM19274049  
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-NAS19274049  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IDA15833715  
GO:0003677DNA binding-IDA7665092  
GO:0005515protein binding-IPI7665092  16189514  20102225  25416956  
GO:0008134transcription factor binding-IDA7665092  
GO:0042803protein homodimerization activity-IEA-  
GO:0043565sequence-specific DNA binding-IDA7665092  
GO:0046982protein heterodimerization activity-IDA7665092  
GO ID GO Term Qualifier Evidence PubMed
GO:0001889liver development-ISS-  
GO:0006357regulation of transcription by RNA polymerase II-IDA16255782  
GO:0006366transcription by RNA polymerase II-IEA-  
GO:0006955immune response-ISS-  
GO:0016071mRNA metabolic process-IEA-  
GO:0030183B cell differentiation-ISS-  
GO:0042267natural killer cell mediated cytotoxicity-ISS-  
GO:0043353enucleate erythrocyte differentiation-ISS-  
GO:0043388positive regulation of DNA binding-TAS7665092  
GO:0043433negative regulation of DNA-binding transcription factor activity-ISS7501458  
GO:0045078positive regulation of interferon-gamma biosynthetic process-ISS-  
GO:0045739positive regulation of DNA repair-IEP16255782  
GO:0045944positive regulation of transcription by RNA polymerase II-IDA15833715  
GO:0051091positive regulation of DNA-binding transcription factor activity-TAS7665092  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-ISS7501458  
GO:0005654nucleoplasm-IDA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
16255782CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma. (2005 Oct 29)Mullins DNBMC Cancer