Gene: IVNS1ABP

10625
ARA3|FLARA3|HSPC068|KLHL39|ND1|NS-1|NS1-BP|NS1BP
influenza virus NS1A binding protein
protein-coding
1q25.3
Ensembl:ENSG00000116679 MIM:609209 Vega:OTTHUMG00000035384 UniprotKB:Q9Y6Y0
NC_000001.11
PubMed
0   ANCO-SNPs
ND|AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.213e-1 (AD)  8.417e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PXK0.821
TIAL10.82
DYNC1I20.819
ZC3H11A0.817
GPBP10.805
FNTB0.803
CTCF0.801
SRSF60.801
CYTH10.799
RBPJ0.798

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.649
OR4F29-0.629
ACOT6-0.19
HORMAD2-0.176
CAV3-0.172
PON3-0.166
HMHB1-0.161
GLI1-0.157
MAP3K19-0.157
ZNF705B-0.156

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of IVNS1ABP mRNA"19162173
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of IVNS1ABP mRNA"21346803
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of IVNS1ABP mRNA"21346803
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]"19467301
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane affects the expression of IVNS1ABP mRNA"18648102
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IVNS1ABP mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IVNS1ABP mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of IVNS1ABP mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of IVNS1ABP gene27153756
D000452AldrinAldrin results in decreased expression of IVNS1ABP mRNA18579281
D000638AmiodaroneAmiodarone results in increased expression of IVNS1ABP mRNA17991464
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of IVNS1ABP mRNA24449571
D001151ArsenicArsenic affects the methylation of IVNS1ABP gene25304211
D001280AtrazineAtrazine results in decreased expression of IVNS1ABP mRNA22378314
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of IVNS1ABP mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IVNS1ABP mRNA20064835|2010694
D001564Benzo(a)pyreneBenzo(a)pyrene affects the expression of IVNS1ABP mRNA22342234
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of IVNS1ABP mRNA"19150397
D004958EstradiolEstradiol results in increased expression of IVNS1ABP mRNA25210133
C006780bisphenol Abisphenol A results in increased expression of IVNS1ABP mRNA25181051
D002220CarbamazepineCarbamazepine affects the expression of IVNS1ABP mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of IVNS1ABP mRNA17484886
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of IVNS1ABP mRNA24763279
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of IVNS1ABP mRNA23650126
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IVNS1ABP mRNA20938992
D002922CiguatoxinsCiguatoxins affects the expression of IVNS1ABP mRNA18353800
D002994ClofibrateClofibrate results in decreased expression of IVNS1ABP mRNA23811191
D002994ClofibrateClofibrate results in increased expression of IVNS1ABP mRNA17585979
D003033Coal TarCoal Tar results in decreased expression of IVNS1ABP mRNA27858113
C018021cobaltous chloridecobaltous chloride results in decreased expression of IVNS1ABP mRNA19320972
D003300CopperCopper results in decreased expression of IVNS1ABP mRNA17205981
D019327Copper SulfateCopper Sulfate results in decreased expression of IVNS1ABP mRNA18579281
D003375CoumestrolCoumestrol results in increased expression of IVNS1ABP mRNA19167446
D003513CycloheximideCycloheximide inhibits the reaction [Doxorubicin results in decreased expression of IVNS1ABP mRNA]17016628
D016572CyclosporineCyclosporine results in increased expression of IVNS1ABP mRNA20106945|2798913
D015638Cytochalasin DIVNS1ABP gene mutant form results in increased susceptibility to Cytochalasin D15485691
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of IVNS1ABP mRNA21266533
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of IVNS1ABP mRNA19030233|1946730
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]19030233
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of IVNS1ABP mRNA25242112
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in increased expression of IVNS1ABP mRNA27638505
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene affects the expression of IVNS1ABP mRNA"21785161
D004317DoxorubicinCycloheximide inhibits the reaction [Doxorubicin results in decreased expression of IVNS1ABP mRNA]17016628
D004317DoxorubicinDoxorubicin results in decreased expression of IVNS1ABP mRNA alternative form16952015
D004317DoxorubicinDoxorubicin results in decreased stability of and results in decreased expression of IVNS1ABP mRNA17016628
D004317DoxorubicinIVNS1ABP gene mutant form results in increased susceptibility to Doxorubicin15485691
D004317DoxorubicinIVNS1ABP results in decreased susceptibility to Doxorubicin16952015
D004997Ethinyl EstradiolEthinyl Estradiol affects the expression of IVNS1ABP mRNA17555576
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of IVNS1ABP mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IVNS1ABP mRNA17942748
D005485FlutamideFlutamide results in decreased expression of IVNS1ABP mRNA24136188
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IVNS1ABP mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of IVNS1ABP mRNA23649840
C039281furanfuran results in increased expression of IVNS1ABP mRNA26194646
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of IVNS1ABP mRNA22634610
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of IVNS1ABP mRNA24763279
D017313FenretinideFenretinide results in increased expression of IVNS1ABP mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of IVNS1ABP mRNA20044591
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IVNS1ABP mRNA25613284
D007649KetamineKetamine results in decreased expression of IVNS1ABP mRNA20080153
D064704LevofloxacinLevofloxacin results in increased expression of IVNS1ABP mRNA24136188
C482199lipopolysaccharide, E coli O55-B5"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IVNS1ABP mRNA"18930950
D008628MercuryMercury results in decreased expression of IVNS1ABP mRNA16823088
D008694MethamphetamineMethamphetamine results in decreased methylation of IVNS1ABP promoter26307267
D008694MethamphetamineMethamphetamine results in increased expression of IVNS1ABP mRNA26307267
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of IVNS1ABP mRNA20938992
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of IVNS1ABP mRNA23179753
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of IVNS1ABP mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of IVNS1ABP mRNA"20188158
D0156551-Methyl-4-phenylpyridinium1-Methyl-4-phenylpyridinium results in decreased expression of IVNS1ABP protein26558463
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of IVNS1ABP mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of IVNS1ABP mRNA"25620056
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of IVNS1ABP mRNA"25554681
C029938nickel sulfatenickel sulfate results in decreased expression of IVNS1ABP mRNA22714537
D010126OzoneOzone results in decreased expression of IVNS1ABP mRNA12763052
C046012pentanalpentanal results in decreased expression of IVNS1ABP mRNA26079696
C014153pirimiphos methylpirimiphos methyl results in decreased expression of IVNS1ABP mRNA27845199
C006253pirinixic acidpirinixic acid results in decreased expression of IVNS1ABP mRNA20813756
C006253pirinixic acidpirinixic acid results in increased expression of IVNS1ABP mRNA18445702
D010936Plant ExtractsPlant Extracts results in increased expression of IVNS1ABP mRNA23557933
D011374ProgesteroneProgesterone results in decreased expression of IVNS1ABP mRNA21795739
D011794QuercetinQuercetin results in decreased expression of IVNS1ABP mRNA21632981
C059514resveratrolresveratrol results in increased expression of IVNS1ABP mRNA22610192
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of IVNS1ABP mRNA]19030233
D012402RotenoneRotenone results in increased expression of IVNS1ABP mRNA19013527
D012822Silicon DioxideSilicon Dioxide results in increased expression of IVNS1ABP mRNA23221170
D013629TamoxifenTamoxifen affects the expression of IVNS1ABP mRNA17555576
D013629TamoxifenTamoxifen results in increased expression of IVNS1ABP mRNA25123088
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IVNS1ABP mRNA20106945|2163298
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of IVNS1ABP mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin binds to AHR protein] which results in decreased expression of IVNS1ABP mRNA16214954
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of IVNS1ABP mRNA17942748
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of IVNS1ABP mRNA25975270
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IVNS1ABP mRNA18796159
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of IVNS1ABP mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IVNS1ABP mRNA18796159|2121527
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IVNS1ABP mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of IVNS1ABP mRNA20133372
D014212TretinoinTretinoin results in increased expression of IVNS1ABP mRNA15894607
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IVNS1ABP mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of IVNS1ABP mRNA26272509
C080163trovafloxacin"[trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IVNS1ABP mRNA"18930950
D014520UrethaneUrethane results in decreased expression of IVNS1ABP mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of IVNS1ABP mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of IVNS1ABP mRNA19101580|2317975
D014635Valproic AcidValproic Acid results in increased expression of IVNS1ABP mRNA25192806
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of IVNS1ABP gene25560391
D014750VincristineVincristine results in decreased expression of IVNS1ABP mRNA23649840
C088658zoledronic acidzoledronic acid results in decreased expression of IVNS1ABP mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI23825951  25619834  
GO ID GO Term Qualifier Evidence PubMed
GO:0006383transcription by RNA polymerase III-TAS9696811  
GO:0008380RNA splicing-IMP23825951  
GO:0009615response to virus-IMP23825951  
GO:0016032viral process-IEA-  
GO:0031397negative regulation of protein ubiquitination-IMP25619834  
GO:2001243negative regulation of intrinsic apoptotic signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IEA-  
GO:0005667transcription factor complex-TAS9696811  
GO:0005681spliceosomal complex-TAS9696811  
GO:0005829cytosol-IDA-  
GO:0015629actin cytoskeleton-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal