Gene: CETN1

1068
CEN1|CETN
centrin 1
protein-coding
18p11.32
Ensembl:ENSG00000177143 MIM:603187 Vega:OTTHUMG00000131471 UniprotKB:Q12798
NC_000018.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.493e-1 (AD)  1.180e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MS4A50.567
POTED0.506
PRAMEF50.433
ESX10.432
TUBA1C0.37
PRM10.364
CCDC630.362
BANF20.36
TAS2R600.36
PRR210.355

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR5B12-0.221
ZNF273-0.214
SLITRK4-0.213
SLC6A5-0.21
PLGLB1-0.207
FAM153A-0.206
VWDE-0.203
SDR9C7-0.196
CCDC73-0.192
SLC25A2-0.188

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D020106AcrylamideAcrylamide results in increased expression of CETN1 mRNA28959563
D001280AtrazineAtrazine results in increased expression of CETN1 mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CETN1 mRNA20504355
C006780bisphenol Abisphenol A results in decreased expression of CETN1 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of CETN1 mRNA26079696
D004041Dietary FatsDietary Fats results in increased expression of CETN1 mRNA25016146
D014635Valproic AcidValproic Acid results in increased methylation of CETN1 gene29154799
D001335Vehicle EmissionsVehicle Emissions affects the methylation of CETN1 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005509calcium ion binding-IBA21873635  
GO:0005509calcium ion binding-IEA-  
GO:0005515protein binding-IPI20643351  25416956  
GO:0008017microtubule binding-IBA21873635  
GO:0008017microtubule binding-IEA-  
GO:0031683G-protein beta/gamma-subunit complex binding-IBA21873635  
GO:0031683G-protein beta/gamma-subunit complex binding-IEA-  
GO:0032795heterotrimeric G-protein binding-IBA21873635  
GO:0032795heterotrimeric G-protein binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000226microtubule cytoskeleton organization-IBA21873635  
GO:0000281mitotic cytokinesis-IBA21873635  
GO:0007049cell cycle-IEA-  
GO:0007099centriole replication-IBA21873635  
GO:0010824regulation of centrosome duplication-IBA21873635  
GO:0019722calcium-mediated signaling-IBA21873635  
GO:0032465regulation of cytokinesis-IBA21873635  
GO:0034605cellular response to heat-IEA-  
GO:0051301cell division-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0000922spindle pole-IDA8175926  
GO:0005634nucleus-IBA21873635  
GO:0005737cytoplasm-IBA21873635  
GO:0005813centrosome-IBA21873635  
GO:0005813centrosome-IDA8175926  
GO:0005813centrosome-IMP18331714  
GO:0005814centriole-IBA21873635  
GO:0005814centriole-IDA18331714  24421332  
GO:0032391photoreceptor connecting cilium-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
26202054Interaction between smoking history and gene expression levels impacts survival of breast cancer patients. (2015 Aug)Andres SABreast Cancer Res Treat