Gene: CETP

1071
BPIFF|HDLCQ10
cholesteryl ester transfer protein
protein-coding
16q13
Ensembl:ENSG00000087237 MIM:118470 Vega:OTTHUMG00000133279 UniprotKB:P11597
NG_008952.1
PubMed
ND|AD
87   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.291e-2 (AD)  6.606e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PZP0.564
IL2RB0.558
FCRL30.548
KLRF10.543
HMCN10.54
MROH50.534
DPPA40.533
NMUR10.532
PROM10.531
C2orf830.526

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CADM1-0.455
GDF10-0.441
SLC1A4-0.44
WFS1-0.424
ADCY2-0.42
CHST1-0.418
SLC6A11-0.415
KLHL21-0.411
TMEM56-0.41
LRRC8A-0.405

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB06281TorcetrapibSmall Molecule262352-17-0InvestigationalTarget
ID Drug Name Action PubMed
C00358522-hydroxycholesterol22-hydroxycholesterol results in increased expression of CETP mRNA16142410
C00358522-hydroxycholesterol[alitretinoin co-treated with 22-hydroxycholesterol] results in increased expression of CETP mRNA16142410
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of CETP gene27153756
C103303alitretinoin[alitretinoin co-treated with 22-hydroxycholesterol] results in increased expression of CETP mRNA16142410
C103303alitretinoin[alitretinoin co-treated with TO-901317] results in increased expression of CETP mRNA16142410
C103303alitretinoinalitretinoin results in increased expression of CETP mRNA16142410
C530884anacetrapibanacetrapib results in decreased activity of CETP protein18414186
C530884anacetrapibanacetrapib results in decreased activity of CETP protein20645987|2561724
C006632arsenic trioxidearsenic trioxide results in increased expression of CETP protein27622732
D001629BezafibrateBezafibrate results in decreased activity of CETP protein12754275
D001629Bezafibrate"[Bezafibrate results in decreased activity of CETP protein] affects the reaction [Bezafibrate results in increased abundance of Cholesterol, HDL]"12754275
D001629BezafibrateBezafibrate inhibits the reaction [Cholesterol results in increased activity of CETP protein]10406588
D001629Bezafibrate[Cholesterol co-treated with Probucol co-treated with Bezafibrate] results in increased activity of CETP protein10406588
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide results in increased expression of CETP mRNA18804290
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of CETP mRNA18804290
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in decreased expression of CETP mRNA18804290
D002784CholesterolTeniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol]25914138
D002784CholesterolBezafibrate inhibits the reaction [Cholesterol results in increased activity of CETP protein]10406588
D002784Cholesterol[Cholesterol co-treated with Probucol co-treated with Bezafibrate] results in increased activity of CETP protein10406588
D002784Cholesterol[Cholesterol co-treated with Probucol] results in increased activity of CETP protein10406588
D002784CholesterolCholesterol results in increased activity of CETP protein10406588
D002791Cholesterol, Dietary"Cholesterol, Dietary results in increased expression of CETP protein"10519734
D008076Cholesterol, HDL"[Bezafibrate results in decreased activity of CETP protein] affects the reaction [Bezafibrate results in increased abundance of Cholesterol, HDL]"12754275
D008076Cholesterol, HDL"CETP gene polymorphism affects the abundance of Cholesterol, HDL"16030523
D008076Cholesterol, HDL"[CETP polymorphism affects the susceptibility to Simvastatin] which affects the abundance of Cholesterol, HDL"17931083
D008076Cholesterol, HDL"CETP protein results in decreased abundance of Cholesterol, HDL"25914138
D008076Cholesterol, HDL"Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol, HDL]"25914138
C018021cobaltous chloridecobaltous chloride results in decreased expression of CETP mRNA24612858
C411602dalcetrapibdalcetrapib results in decreased activity of CETP protein18414186
C411602dalcetrapibdalcetrapib results in decreased activity of CETP protein20645987|2561724
D005047EtoposideEtoposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]25914138
D005047EtoposideEtoposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]25914138
D005047EtoposideEtoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]25914138
D005047EtoposideEtoposide results in increased expression of CETP mRNA25914138
D005047EtoposideEtoposide results in increased expression of CETP protein25914138
D005047EtoposideNR1H2 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]25914138
D005047EtoposideNR1H3 mutant form inhibits the reaction [Etoposide results in increased expression of CETP mRNA]25914138
D005047Etoposide[Tretinoin co-treated with Etoposide] results in increased expression of CETP mRNA25914138
D005047EtoposideTretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]25914138
D005047EtoposideTretinoin promotes the reaction [Etoposide results in increased expression of CETP protein]25914138
C061365flusilazoleflusilazole results in decreased expression of CETP mRNA22382673
C061365flusilazoleflusilazole results in increased expression of CETP mRNA22382673
C065180fluvastatin[ABCA1 gene SNP co-treated with CETP gene SNP co-treated with LIPC gene SNP co-treated with LPL gene SNP] affects the susceptibility to fluvastatin19773416
C065180fluvastatin[APOB gene SNP co-treated with APOE gene SNP co-treated with HMGCR gene SNP co-treated with LDLR gene SNP co-treated with PCSK9 gene SNP co-treated with ABCA1 gene SNP co-treated with CETP gene SNP co-treated with LIPC gene SNP co-treated with LPL gene SNP] affects the susceptibility to fluvastatin19773416
D005557FormaldehydeFormaldehyde results in increased expression of CETP mRNA23649840
D005632FructoseFructose results in increased expression of and results in increased activity of CETP protein11476189
D005632FructoseFructose results in increased expression of CETP mRNA11476189
C473027GW 3965GW 3965 results in increased expression of CETP mRNA19426978
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of CETP mRNA26011545
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of CETP mRNA23649840
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased expression of CETP mRNA]22056562
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [APOA1 protein results in increased secretion of CETP protein]22056562
D019829NevirapineNevirapine results in increased expression of CETP protein19667106
D059808PolyphenolsPolyphenols results in decreased activity of CETP protein16046716
D011341Probucol[Cholesterol co-treated with Probucol co-treated with Bezafibrate] results in increased activity of CETP protein10406588
D011341Probucol[Cholesterol co-treated with Probucol] results in increased activity of CETP protein10406588
D019821SimvastatinCETP polymorphism affects the susceptibility to Simvastatin16038892|1793108
D019821Simvastatin"[CETP polymorphism affects the susceptibility to Simvastatin] which affects the abundance of Cholesterol, HDL"17931083
D019821Simvastatin[CETP polymorphism affects the susceptibility to Simvastatin] which affects the abundance of Triglycerides17931083
D019821SimvastatinSimvastatin results in decreased expression of CETP protein10519734
C009277sodium arsenatesodium arsenate results in decreased expression of CETP mRNA23922661
C016104sodium bichromatesodium bichromate results in decreased expression of CETP mRNA24612858
D013713TeniposideCETP protein promotes the reaction [Teniposide results in decreased abundance of Triglycerides]25914138
D013713TeniposideNR1H2 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]25914138
D013713TeniposideNR1H3 mutant form inhibits the reaction [Teniposide results in increased expression of CETP mRNA]25914138
D013713TeniposideTeniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol]25914138
D013713Teniposide"Teniposide promotes the reaction [CETP protein results in decreased abundance of Cholesterol, HDL]"25914138
D013713TeniposideTeniposide promotes the reaction [CETP protein results in decreased abundance of Triglycerides]25914138
D013713TeniposideTeniposide promotes the reaction [NR1H2 protein results in increased expression of CETP mRNA]25914138
D013713TeniposideTeniposide promotes the reaction [NR1H3 protein results in increased expression of CETP mRNA]25914138
D013713TeniposideTeniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]25914138
D013713TeniposideTeniposide results in increased expression of and results in increased secretion of CETP protein25914138
D013713TeniposideTeniposide results in increased expression of CETP mRNA25914138
D013713Teniposide[Tretinoin co-treated with Teniposide] results in increased expression of CETP mRNA25914138
D013713TeniposideTretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]25914138
D013713TeniposideTretinoin promotes the reaction [Teniposide results in increased expression of CETP protein]25914138
D013713TeniposideTeniposide promotes the reaction [CETP protein results in decreased expression of MTTP mRNA]25914138
C423915TO-901317[alitretinoin co-treated with TO-901317] results in increased expression of CETP mRNA16142410
C423915TO-901317TO-901317 results in increased expression of CETP mRNA16142410|1942697
C483909torcetrapibtorcetrapib results in decreased activity of CETP protein18414186|2002678
C483909torcetrapibtorcetrapib results in decreased activity of CETP protein19164467|2064598
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased expression of CETP mRNA]22056562
D014108Tosylphenylalanyl Chloromethyl KetoneTosylphenylalanyl Chloromethyl Ketone promotes the reaction [APOA1 protein results in increased secretion of CETP protein]22056562
D014212Tretinoin[Tretinoin co-treated with Etoposide] results in increased expression of CETP mRNA25914138
D014212Tretinoin[Tretinoin co-treated with Teniposide] results in increased expression of CETP mRNA25914138
D014212TretinoinTretinoin promotes the reaction [Etoposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]25914138
D014212TretinoinTretinoin promotes the reaction [Etoposide results in increased expression of CETP protein]25914138
D014212TretinoinTretinoin promotes the reaction [RXRA protein results in increased expression of CETP mRNA]25914138
D014212TretinoinTretinoin promotes the reaction [Teniposide promotes the reaction [RXRA protein results in increased expression of CETP mRNA]]25914138
D014212TretinoinTretinoin promotes the reaction [Teniposide results in increased expression of CETP protein]25914138
D014212TretinoinTretinoin results in increased expression of CETP mRNA25914138
D014280Triglycerides[CETP polymorphism affects the susceptibility to Simvastatin] which affects the abundance of Triglycerides17931083
D014280TriglyceridesCETP protein promotes the reaction [Teniposide results in decreased abundance of Triglycerides]25914138
D014280TriglyceridesCETP protein results in decreased abundance of Triglycerides25914138
D014280TriglyceridesTeniposide promotes the reaction [CETP protein results in decreased abundance of Triglycerides]25914138
D014635Valproic AcidValproic Acid results in increased methylation of CETP gene29154799
D014750VincristineVincristine results in increased expression of CETP mRNA23649840

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005319lipid transporter activity-IDA2833496  
GO:0005548phospholipid transporter activity-IDA2833496  
GO:0008289lipid binding-IDA3818596  
GO:0015485cholesterol binding-IDA2833496  
GO:0017127cholesterol transporter activity-IDA2833496  3600759  24293641  
GO:0017129triglyceride binding-IDA2833496  
GO:0031210phosphatidylcholine binding-IDA2833496  
GO ID GO Term Qualifier Evidence PubMed
GO:0006641triglyceride metabolic process-IDA2833496  
GO:0006869lipid transport-IDA3818596  
GO:0008203cholesterol metabolic process-IDA2833496  
GO:0008203cholesterol metabolic process-IMP2586614  
GO:0010745negative regulation of macrophage derived foam cell differentiation-IC16670775  
GO:0010874regulation of cholesterol efflux-IMP16670775  
GO:0015914phospholipid transport-IDA2833496  
GO:0030301cholesterol transport-IDA2833496  24293641  
GO:0034197triglyceride transport-IDA24293641  
GO:0034372very-low-density lipoprotein particle remodeling-IDA2833496  24293641  
GO:0034374low-density lipoprotein particle remodeling-IDA2833496  
GO:0034374low-density lipoprotein particle remodeling-TAS-  
GO:0034375high-density lipoprotein particle remodeling-IDA24293641  
GO:0034375high-density lipoprotein particle remodeling-IMP2586614  
GO:0034375high-density lipoprotein particle remodeling-TAS-  
GO:0042632cholesterol homeostasis-IMP2586614  
GO:0043691reverse cholesterol transport-IC7583561  
GO:0046470phosphatidylcholine metabolic process-IDA2833496  
GO:0055088lipid homeostasis-IDA3818596  
GO:0055091phospholipid homeostasis-IDA2833496  
GO:0070328triglyceride homeostasis-IDA2833496  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-IDA3104518  24293641  
GO:0031982vesicle-IDA2833496  
GO:0034364high-density lipoprotein particle-IDA3104518  
GO:0070062extracellular exosome-HDA19056867  23533145  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-174824Plasma lipoprotein assembly, remodeling, and clearanceTAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-8963899Plasma lipoprotein remodelingTAS
R-HSA-8964041LDL remodelingTAS
R-HSA-8964058HDL remodelingTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
11888533A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men. (2002 Apr)Liu SAtherosclerosis
8566946Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors. (1996 Feb)Kauma HHum Genet
9670349High-density lipoprotein cholesterol is related to the TaqIB cholesteryl ester transfer protein gene polymorphism and smoking, but not to moderate alcohol consumption in insulin-dependent diabetic men. (1998 May)Dullaart RPScand J Clin Lab Invest
18187430The lipoprotein lipase serine 447 stop polymorphism is associated with altered serum carotenoid concentrations in the Stanislas Family Study. (2007 Dec)Herbeth BJ Am Coll Nutr
27478449Serum CETP and PLTP activity in middle-aged men living in urban or rural area of the Lower Silesia region. PURE Poland sub-study. (2016 Aug 1)Skoczynska AArch Med Sci
24608419Elevated high-density lipoprotein cholesterol and age-related macular degeneration: the Alienor study. (2014)Cougnard-Gregoire APLoS One
18480348Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels. (2008 Jun)Hausenloy DJHeart
12821213Secondary prevention in coronary heart disease patients with low HDL: which options do we have? (2003 Jul)Liem AHInt J Cardiol
22003152Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. (2012 Jan)Grallert HEur Heart J
15996208An interaction between the TaqIB polymorphism of cholesterol ester transfer protein and smoking is associated with changes in plasma high-density lipoprotein cholesterol levels in Turks. (2005 Aug)Hodoglugil UClin Genet
22235250Quantile-specific penetrance of genes affecting lipoproteins, adiposity and height. (2012)Williams PTPLoS One
9555865Molecular genetic study of Finns with hypoalphalipoproteinemia and hyperalphalipoproteinemia: a novel Gly230 Arg mutation (LCAT[Fin]) of lecithin:cholesterol acyltransferase (LCAT) accounts for 5% of cases with very low serum HDL cholesterol levels. (1998 Apr)Miettinen HEArterioscler Thromb Vasc Biol
22941786Relationship between atorvastatin dose and the harm caused by torcetrapib. (2012 Nov)Barter PJJ Lipid Res
24267222Controlling for apolipoprotein A-I concentrations changes the inverse direction of the relationship between high HDL-C concentration and a measure of pre-clinical atherosclerosis. (2013 Dec)Sung KCAtherosclerosis
11714857Genetic influences on lipid metabolism trait variability within the Stanislas Cohort. (2001 Nov)Pallaud CJ Lipid Res
9387148The effects of the cholesterol ester transfer protein gene and environmental factors on the plasma high density lipoprotein cholesterol levels in the Korean population. (1997 Oct 31)Song GJMol Cells
20430392No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels. (2010 Aug)Marques-Vidal PAtherosclerosis
9084928Interaction of the cholesteryl ester transfer protein I405V polymorphism with alcohol consumption in smoking and non-smoking healthy men, and the effect on plasma HDL cholesterol and apoAI concentration. (1997 Jan)Gudnason VClin Genet
12519369The association of cholesteryl ester transfer protein polymorphism with high-density lipoprotein cholesterol and coronary artery disease in Koreans. (2003 Jan)Park KWClin Genet
22460205Genetic variants at the APOE, lipoprotein lipase (LpL), cholesteryl ester transfer protein (CETP), and endothelial nitric oxide (eNOS) genes and coronary artery disease (CAD): CETP Taq1 B2B2 associates with lower risk of CAD in Asian Indians. (2010 Jun)Bhanushali AAJ Community Genet
15655129Cholesteryl ester transfer protein TaqIB variant, high-density lipoprotein cholesterol levels, cardiovascular risk, and efficacy of pravastatin treatment: individual patient meta-analysis of 13,677 subjects. (2005 Jan 25)Boekholdt SMCirculation
15254877Smoking prevents the intravascular remodeling of high-density lipoprotein particles: implications for reverse cholesterol transport. (2004 Jul)Zaratin ACMetabolism
16674961The association between high-density lipoprotein cholesterol level and cholesteryl ester transfer protein TaqIB gene polymorphism is influenced by alcohol drinking in a population-based sample. (2007 Mar)Tsujita YAtherosclerosis
14967821A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly. (2004 May)Curb JDJ Lipid Res
19056069Association of the cholesteryl ester transfer protein Taq1 B2B2 genotype with higher high-density lipoprotein cholesterol concentrations and lower risk of coronary artery disease in a Tunisian population. (2008 Oct)Rejeb JArch Cardiovasc Dis
18393253[Association of CETP and CRP gene polymorphisms with non-valvular atrial fibrillation in Chinese Han population]. (2008 Apr)Yang WYZhonghua Yi Xue Yi Chuan Xue Za Zhi
24283500CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population. (2013 Nov 27)Wang JLipids Health Dis
19878569Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis. (2009 Oct 30)Chen SNBMC Med Genet
27827461Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population. (2016 Nov 9)Lin ESci Rep
25541553Adiposity is associated with DNA methylation profile in adipose tissue. (2015 Aug)Agha GInt J Epidemiol
28209224Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. (2017 Feb 21)Webb TRJ Am Coll Cardiol
23950155Association between the cholesteryl ester transfer protein gene and polypoidal choroidal vasculopathy. (2013 Sep 9)Nakata IInvest Ophthalmol Vis Sci
11359462APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort). (2001 May)Pallaud CClin Genet
20581105Gene-environment interactions of CETP gene variation in a high cardiovascular risk Mediterranean population. (2010 Sep)Corella DJ Lipid Res
28128572[Genetic determination of dyslipidemia - What tell us the results of genome-wide association studies?] (Fall 2016)Hubacek JAVnitr Lek
18956684[Study on the correlation between CETP TaqIB, KCNE1 S38G and eNOS T-786C gene polymorphisms for predisposition and non-valvular atrial fibrillation]. (2008 May)Xu LXZhonghua Liu Xing Bing Xue Za Zhi
17587762Human cholestryl ester transfer protein (TaqIB) polymorphism among Filipinos with cardiovascular risk factors. (2007 Jun)Sy RGJ Atheroscler Thromb
21589926Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks. (2011 May 11)Turner SDPLoS One
16426594The effect of the APOE polymorphism on HDL-C concentrations depends on the cholesterol ester transfer protein gene variation in a Southern European population. (2006 Apr)Sorli JVClin Chim Acta
11575217[APOC3, CETP, beta-fibrinogen and MTHFR are genetic determinants of carotid intim-media thickness (Stanislas cohort)]. (2001 Aug)Pallaud CArch Mal Coeur Vaiss
25993681Reassessing lipid metabolism and its potentialities in the prediction of cardiovascular risk. (2015 Apr)Silva ITArch Endocrinol Metab
9102177Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels. (1997 Mar)Kuivenhoven JAArterioscler Thromb Vasc Biol
9684753Decreased postprandial high density lipoprotein cholesterol and apolipoproteins A-I and E in normolipidemic smoking men: relations with lipid transfer proteins and LCAT activities. (1998 Jul)Mero NJ Lipid Res
10998464Association of TaqIB polymorphism in the cholesteryl ester transfer protein gene with plasma lipid levels in a healthy Spanish population. (2000 Oct)Corella DAtherosclerosis
9392500Cholesteryl ester transfer protein gene polymorphism is a determinant of HDL cholesterol and of the lipoprotein response to a lipid-lowering diet in type 1 diabetes. (1997 Dec)Dullaart RPDiabetes
23852759Effects of cigarette smoking on HDL quantity and function: implications for atherosclerosis. (2013 Nov)He BMJ Cell Biochem
17970962Polymorphism in the cholesteryl ester transfer protein gene and the risk of early onset myocardial infarction among cigarette smokers. (2007 Oct)Goldenberg IAnn Noninvasive Electrocardiol
14563342A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. (2003 Oct)Freeman DJEur Heart J
1476558Evaluation of plasma cholesteryl ester transfer protein (CETP) activity as a marker of alcoholism. (1992 Sep)Hannuksela MAlcohol Alcohol
17991668Interaction between dietary fat intake and the cholesterol ester transfer protein TaqIB polymorphism in relation to HDL-cholesterol concentrations among US diabetic men. (2007 Nov)Li TYAm J Clin Nutr
19876761Protective modulation of carotid atherosclerosis in hyperalphalipoproteinemic individuals. (2010 Jan)Santiago FDInt J Cardiovasc Imaging
25893111Association of OCT derived drusen measurements with AMD associated-genotypic SNPs in Amish population. (2015)Chavali VRJ Clin Med
10807749Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham study. (2000 May)Ordovas JMArterioscler Thromb Vasc Biol
12820950[Study on the distribution and association of cholesteryl ester transfer protein-TaqIB polymorphism and plasma concentration in general population]. (2003 Apr)Liu JZhonghua Liu Xing Bing Xue Za Zhi
12033532Association of human cholesteryl ester transfer protein-TaqI polymorphisms with serum HDL cholesterol levels in a normolipemic Japanese rural population. (2002 Mar)Chen JJ Epidemiol
19103817Targeting residual cardiovascular risk: raising high-density lipoprotein cholesterol levels. (2008 Nov)Hausenloy DJPostgrad Med J
27899788Serum Lipid Transfer Proteins in Hypothyreotic Patients Are Inversely Correlated with Thyroid-Stimulating Hormone (TSH) Levels. (2016 Nov 30)Skoczynska AMed Sci Monit
7857368Relation of polymorphisms in the cholesteryl ester transfer protein gene to transfer protein activity and plasma lipoprotein levels in alcohol drinkers. (1994 Sep 30)Hannuksela MLAtherosclerosis
24376512Gene-gene combination effect and interactions among ABCA1, APOA1, SR-B1, and CETP polymorphisms for serum high-density lipoprotein-cholesterol in the Japanese population. (2013)Nakamura APLoS One
7907227Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqI B RFLP in the CETP gene and smoking and obesity. (1994 Mar)Freeman DJArterioscler Thromb
15039035Genetic risk factors for stroke and carotid atherosclerosis: insights into pathophysiology from candidate gene approaches. (2004 Apr)Humphries SELancet Neurol
28906356Shared polymorphisms and modifiable behavior factors for myocardial infarction and high cholesterol in a retrospective population study. (2017 Sep)Liang YMedicine (Baltimore)
20842556High-density lipoprotein therapy: is there hope? (2010 Aug)Bhatt KNCurr Treat Options Cardiovasc Med
8971092Macrovascular disease is associated with increased plasma apolipoprotein A-IV levels in NIDDM. (1997 Jan)Verges BLDiabetes
18221399Glucocorticoid replacement is associated with hypertriglyceridaemia, elevated glucose and higher non-HDL cholesterol and may diminish the association of HDL cholesterol with the -629C>A CETP promoter polymorphism in GH-receiving hypopituitary patients. (2008 Sep)Dullaart RPClin Endocrinol (Oxf)
15469403Pharmacogenomics and drug response in cardiovascular disorders. (2004 Oct)Siest GPharmacogenomics
7918308Higher plasma lipid transfer protein activities and unfavorable lipoprotein changes in cigarette-smoking men. (1994 Oct)Dullaart RPArterioscler Thromb
9543093R451Q mutation in the cholesteryl ester transfer protein (CETP) gene is associated with high plasma CETP activity. (1998 Feb)Kakko SAtherosclerosis
7474298CETP and LCAT activities are unrelated to smoking and moderate alcohol consumption in healthy normolipidemic men. (1995 Aug)Ito TJpn Circ J
23758630Association of CETP Taq1B and -629C > A polymorphisms with coronary artery disease and lipid levels in the multi-ethnic Singaporean population. (2013 Jun 8)Lu YLipids Health Dis
24615107Relationship between the TaqI B polymorphism of the cholesterol ester transfer protein gene and atrial fibrillation in Han and Kazak populations. (2014 Feb 14)Bakeyi MGenet Mol Res
28167353Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants. (2017 Mar)Shahid SUAtherosclerosis
2060438Elevated cholesteryl ester transfer protein activity in IDDM men who smoke. Possible factor for unfavorable lipoprotein profile. (1991 Apr)Dullaart RPDiabetes Care
8281981Smoking and plasma lipoproteins in man: effects on low density lipoprotein cholesterol levels and high density lipoprotein subfraction distribution. (1993 Oct)Freeman DJEur J Clin Invest
20799898Cholesteryl ester transfer protein Taq1B polymorphism in an angiographically assessed Turkish population: no effects on coronary artery disease risk. (2010 Oct)Tanrikulu-Kucuk SGenet Test Mol Biomarkers
14669156Association of cholesteryl ester transfer protein activity and TaqIB polymorphism with lipoprotein variations in Japanese subjects. (2003 Dec)Ikewaki KMetabolism
19784962Association of cholesteryl ester transfer protein -629C > A polymorphism with high-density lipoprotein cholesterol levels in coronary artery disease patients. (2009 Oct)Tanrikulu SCell Biochem Funct
28070240Newer perspectives of coronary artery disease in young. (2016 Dec 26)Aggarwal AWorld J Cardiol
19822408Association of Taq 1B CETP polymorphism with insulin and HOMA levels in the population of the Canary Islands. (2011 Jan)Lopez-Rios LNutr Metab Cardiovasc Dis
21447678Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration. (2011 Jun 28)Yu YInvest Ophthalmol Vis Sci
8645374CETP is a determinant of serum LDL-cholesterol but not HDL-cholesterol in healthy Japanese. (1996 Feb)Kinoshita MAtherosclerosis
15939053CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease. (2005 Jul)Thompson JFAtherosclerosis
12174215Genetic and environmental determinants of plasma high density lipoprotein cholesterol and apolipoprotein AI concentrations in healthy middle-aged men. (2002 Mar)Talmud PJAnn Hum Genet
18063597Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women. (2008 Jan)Jensen MKEur Heart J
9726040The effect of smoking on post-heparin lipoprotein and hepatic lipase, cholesteryl ester transfer protein and lecithin:cholesterol acyl transferase activities in human plasma. (1998 Jul)Freeman DJEur J Clin Invest
26820801Serum CETP concentration is not associated with measures of body fat: The NEO study. (2016 Mar)Blauw LLAtherosclerosis
12889988Moderate hyperalphalipoproteinaemia in a Brazilian population is related to lipoprotein lipase activity, apolipoprotein A-I concentration, age and body mass index. (2004 Jan)Alarcon SBClin Sci (Lond)