Gene: CFTR

1080
ABC35|ABCC7|CF|CFTR/MRP|MRP7|TNR-CFTR|dJ760C5.1
cystic fibrosis transmembrane conductance regulator
protein-coding
7q31.2
Ensembl:ENSG00000001626 MIM:602421 Vega:OTTHUMG00000023076 UniprotKB:P13569
NG_016465.4
PubMed
ND|AD
45   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.063e-1 (AD)  8.588e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FRMD4B0.794
TRIM590.778
SH3TC20.768
SGK20.765
CCNE20.765
CREB50.76
NIPAL40.758
TMC70.757
ENOSF10.757
C21orf910.753

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC29A4-0.367
NANOS3-0.338
NGB-0.337
PRTN3-0.331
CHRNA2-0.328
GPR153-0.325
CUX2-0.323
CXCL14-0.318
CALB2-0.318
TCERG1L-0.316

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00171ATPSmall Molecule56-65-5Investigational|NutraceuticalTarget
DB00887BumetanideSmall Molecule28395-03-1ApprovedTarget
DB01016GlyburideSmall Molecule10238-21-8ApprovedTarget
DB01050IbuprofenSmall Molecule15687-27-1ApprovedTarget
DB02587ColforsinSmall Molecule66575-29-9Experimental|InvestigationalTarget
DB04395Phosphoaminophosphonic Acid-Adenylate EsterSmall MoleculeExperimentalTarget
DB04522DexfosfoserineSmall Molecule407-41-0ExperimentalTarget
DB04941CrofelemerSmall Molecule148465-45-6ApprovedTarget
DB06266LonidamineSmall Molecule50264-69-2InvestigationalTarget
DB08820IvacaftorSmall Molecule873054-44-5ApprovedTarget
DB09213DexibuprofenSmall Molecule51146-56-6Approved|InvestigationalTarget
DB09280LumacaftorSmall Molecule936727-05-8ApprovedTarget
DB11712TezacaftorSmall Molecule1152311-62-0Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0252051,10-phenanthroline"1,10-phenanthroline results in increased activity of CFTR protein"15921678
C0789861,2,3,4-tetrahydroisoquinoline-3-carboxylic acid"1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid analog results in increased activity of CFTR protein mutant form"15808474
C0703791,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]"15763242
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of CFTR mRNA"22698814
C0388061,4-dihydropyridine"1,4-dihydropyridine analog results in increased activity of CFTR protein mutant form"21568323
C4560291-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide"1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl)-2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide results in decreased activity of CFTR protein"15685210
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Butyrates results in increased expression of and affects the localization of CFTR protein]15304546
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C0939732-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased expression of CFTR protein mutant form15304546
C1111182',3,3',4',5-pentachloro-4-hydroxybiphenyl"2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CFTR mRNA"19114083
C0859112-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C0143282-amino-4-phenylbutyric acid2-amino-4-phenylbutyric acid results in decreased activity of CFTR protein15857825
C0679432-octanol2-octanol results in increased activity of CFTR protein14967738
C109154(2-(trimethylammonium)ethyl)methanethiosulfonate(2-(trimethylammonium)ethyl)methanethiosulfonate binds to and affects the activity of CFTR protein15504728
C5844693-(2-benzyloxyphenyl)-5-chloromethylisoxazole3-(2-benzyloxyphenyl)-5-chloromethylisoxazole results in increased phosphorylation of CFTR protein25946147
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein15371258
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein15496164
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [CFTR protein results in increased export of Chlorides]20675434
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein15131065|1537125
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in increased activity of CFTR protein15001557
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Enterotoxins results in increased activity of CFTR protein]14762788
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein15246976|1576193
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Enterotoxins results in increased activity of CFTR protein]14762788
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein15905414
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in increased activity of CFTR protein15001557
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [resveratrol results in increased activity of CFTR protein]24147347
C4829003-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone results in decreased activity of CFTR protein21707078|2594614
C0678513-(4-azidobenzoyl)-6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thiophene3-(4-azidobenzoyl)-6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thiophene binds to CFTR protein10991979
C0678513-(4-azidobenzoyl)-6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thiophene3-(4-azidobenzoyl)-6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thiophene results in decreased activity of CFTR protein10991979
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C4954504-chlorobenzo(f)isoquinoline4-chlorobenzo(f)isoquinoline results in increased activity of CFTR protein15148241|1592167
C4954504-chlorobenzo(f)isoquinoline4-chlorobenzo(f)isoquinoline results in increased activity of CFTR protein mutant form15921678
C5072554-cyclohexyloxy-2-(1-(4-(4-methoxy-benzenesulfonyl)piperazin-1-yl)ethyl)quinazoline4-cyclohexyloxy-2-(1-(4-(4-methoxy-benzenesulfonyl)piperazin-1-yl)ethyl)quinazoline results in increased folding of and results in increased localization of and results in increased activity of CFTR protein mutant form21602569
C0757734-phenylbutyric acid4-phenylbutyric acid results in increased activity of and affects the localization of CFTR protein mutant form14583596
C0757734-phenylbutyric acid4-phenylbutyric acid results in increased activity of CFTR protein mutant form15191910
C0757734-phenylbutyric acid4-phenylbutyric acid results in increased stability of and affects the localization of CFTR protein15880796
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride affects the localization of CFTR protein mutant form18230692
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride"[5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form"15163550
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride[5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with Colforsin] results in increased activity of CFTR protein mutant form15163550
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride results in increased activity of CFTR protein14761197
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride results in increased activity of CFTR protein mutant form14761197|1823069
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride results in increased stability of and affects the localization of CFTR protein mutant form14967738
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride results in increased activity of CFTR protein15020588
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chlorideGlyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein]17596272
C4394255-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein17596272
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium affects the localization of CFTR protein mutant form18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein14761197
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form14761197|1823069
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumBrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumBrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumgeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumbenzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
C4831985-butyl-7-chloro-6-hydroxybenzo(c)quinoliziniumgeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein15496164
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid analog binds to and results in increased activity of CFTR protein15857825
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid analog binds to and results in increased activity of CFTR protein mutant form15857825
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of CFTR protein15857825
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid binds to and results in increased activity of CFTR protein mutant form15857825
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein15131065|1527757
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein15389550
C0581765-nitro-2-(3-phenylpropylamino)benzoic acid5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein15711774|1592532
C0581765-nitro-2-(3-phenylpropylamino)benzoic acidGenistein promotes the reaction [5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein]15925323
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
C4519016-hydroxy-10-chlorobenzo(c)quinolizinium6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
C4519016-hydroxy-10-chlorobenzo(c)quinolizinium6-hydroxy-10-chlorobenzo(c)quinolizinium results in increased activity of CFTR protein14761197
C4519016-hydroxy-10-chlorobenzo(c)quinolizinium6-hydroxy-10-chlorobenzo(c)quinolizinium results in increased activity of CFTR protein mutant form18230692
C4519016-hydroxy-10-chlorobenzo(c)quinolizinium6-hydroxy-10-chlorobenzo(c)quinolizinium results in increased activity of CFTR protein15020588
C4519016-hydroxy-10-chlorobenzo(c)quinolizinium[Phenylephrine co-treated with 6-hydroxy-10-chlorobenzo(c)quinolizinium] results in increased activity of CFTR protein17596272
C1172987,8-benzoquinoline"7,8-benzoquinoline promotes the reaction [CFTR protein affects the secretion of Chlorides]"12967937
C1172987,8-benzoquinoline"7,8-benzoquinoline results in increased activity of CFTR protein"12967937|1592167
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"[1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein"15161604
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"[1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form"15163550
C0159298-((4-chlorophenyl)thio)cyclic-3',5'-AMP"[5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form"15163550
C0100309-anthroic acid9-anthroic acid results in decreased activity of CFTR protein15140627
C0100309-anthroic acid9-anthroic acid results in decreased activity of CFTR protein15290302
C0100309-anthroic acid9-anthroic acid results in increased activity of CFTR protein mutant form15290302
C0100309-anthroic acid9-anthroic acid results in decreased activity of CFTR protein15140627
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]19061877
D000111AcetylcysteineAcetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein]19061877
C006303acivicinacivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]14766015
C006303acivicinacivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of CFTR mRNA]14766015
D000241AdenosineAdenosine results in increased activity of CFTR protein15039139
D000241Adenosine[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein15039139
D000242Cyclic AMPCyclic AMP results in increased activity of CFTR protein15371258
D000242Cyclic AMPCyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates]11786964
D000242Cyclic AMPCyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides]11786964
D000242Cyclic AMPCyclic AMP results in increased activity of CFTR protein15229107|1537125
D000242Cyclic AMPGenistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form]12556293
D000242Cyclic AMPCFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]12612912
D000242Cyclic AMPCyclic AMP affects the localization of and results in increased activity of CFTR protein12529251
D000242Cyclic AMPNitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]12612912
D000242Cyclic AMPNocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]12529251
D000242Cyclic AMPPrimaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]12529251
D000242Cyclic AMPCyclic AMP results in increased activity of CFTR protein15229107
D000242Cyclic AMPCyclic AMP results in increased activity of CFTR protein12519749
D000244Adenosine DiphosphateAdenosine Diphosphate binds to and results in decreased activity of CFTR protein15684079
D000244Adenosine Diphosphate"P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein]"15684079
D000255Adenosine Triphosphate3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
D000255Adenosine TriphosphateAdenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]17178710
D000255Adenosine TriphosphateAdenosine Triphosphate binds to and results in increased activity of CFTR protein15623556
D000255Adenosine TriphosphateAdenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]20675434
D000255Adenosine Triphosphate"[Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein"14710196
D000255Adenosine TriphosphateAdenosine Triphosphate results in increased activity of CFTR protein15240343
D000266Adenylyl ImidodiphosphateAdenylyl Imidodiphosphate affects the activity of CFTR protein15657297
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CFTR mRNA23630614
C031143AICA ribonucleotideAICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein]12519745
C095512alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]"19061877
D024502alpha-Tocopherolalpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein]20363832
D000584AmilorideAmiloride results in increased activity of CFTR protein15246976
D000584AmilorideAmiloride results in increased activity of CFTR protein15246976
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CFTR mRNA16483693
C010680antibiotic G 418antibiotic G 418 results in increased expression of CFTR protein mutant form17541014
D047310ApigeninApigenin affects the localization of CFTR protein mutant form15191910
D047310ApigeninApigenin results in increased activity of CFTR protein15277574
D047310ApigeninApigenin results in increased activity of CFTR protein mutant form15191910
D001151ArsenicArsenic inhibits the reaction [CFTR protein results in increased secretion of Chlorides]17038445
D001151ArsenicArsenic inhibits the reaction [SGK1 protein results in increased activity of CFTR protein]20207026
D001151ArsenicArsenic results in decreased activity of CFTR protein17038445
D001151ArsenicArsenic results in decreased expression of and affects the localization of CFTR protein20207026
D001151ArsenicArsenic results in decreased expression of CFTR protein17038445
D001151ArsenicArsenic results in increased ubiquitination of and results in increased degradation of CFTR protein20207026
C015001arsenitearsenite results in decreased methylation of CFTR promoter23974009
D001205Ascorbic AcidAscorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides]14993613
D001205Ascorbic AcidAscorbic Acid results in increased activity of CFTR protein14993613
D001418BaclofenBaclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]15151902
C006680baicaleinbaicalein results in increased activity of CFTR protein15234961
D001507BeclomethasoneBeclomethasone results in increased expression of CFTR mRNA23656298
C487081belinostatbelinostat results in decreased expression of CFTR mRNA27188386
C039108benzo(f)quinolinebenzo(f)quinoline results in increased activity of CFTR protein15921678
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C072553benzyloxycarbonylleucyl-leucyl-leucine aldehydebenzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
D004958EstradiolEstradiol results in increased expression of CFTR mRNA15471937
D004958EstradiolEstradiol results in increased expression of CFTR protein15471937
D004958Estradiol[Progesterone co-treated with Estradiol] results in decreased expression of CFTR mRNA17404688
D004958EstradiolEstradiol affects the expression of CFTR mRNA15598610
D004958EstradiolEstradiol results in increased expression of CFTR mRNA15289156
D004958Estradiol[bisphenol A co-treated with Estradiol] results in increased expression of CFTR mRNA26496021
D001639Bicarbonates[Bicarbonates co-treated with sodium bisulfite] results in increased phosphorylation of CFTR protein12519749
D001639BicarbonatesBicarbonates results in increased phosphorylation of CFTR protein12519749|1511740
D001639BicarbonatesBicarbonates results in decreased activity of CFTR protein15286085
D001639BicarbonatesCFTR protein mutant form results in decreased transport of Bicarbonates11786964
D001639BicarbonatesCFTR protein results in increased transport of Bicarbonates11786964
D001639BicarbonatesCyclic AMP promotes the reaction [CFTR protein results in increased transport of Bicarbonates]11786964
D001639BicarbonatesCFTR protein affects the transport of Bicarbonates14679199|1565013
D001639BicarbonatesCFTR protein mutant form results in decreased secretion of Bicarbonates15480994
D001639BicarbonatesCFTR protein mutant form results in decreased transport of Bicarbonates15650130
D001639BicarbonatesGlyburide inhibits the reaction [CFTR protein affects the transport of Bicarbonates]15650130
D001647Bile Acids and SaltsBile Acids and Salts results in increased activity of CFTR protein16037545
C006780bisphenol Abisphenol A affects the expression of CFTR mRNA25181051
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in increased expression of CFTR mRNA26496021
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in decreased expression of CFTR mRNA26496021
D020126Brefeldin ABrefeldin A results in decreased activity of CFTR protein15371258
D020126Brefeldin ABrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D020126Brefeldin ABrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
D020126Brefeldin ABrefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D020126Brefeldin ABrefeldin A inhibits the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
D020126Brefeldin ABrefeldin A results in decreased activity of CFTR protein15371258
D000068438Brimonidine TartrateBrimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D001966BromineBromine results in decreased activity of CFTR protein15286085
D002034BumetanideBumetanide results in decreased activity of CFTR protein15131065|1580261
D0200011-Butanol1-Butanol results in decreased expression of and results in decreased secretion of CFTR protein17936375
D0200011-ButanolPhosphatidic Acids inhibits the reaction [1-Butanol results in decreased expression of and results in decreased secretion of CFTR protein]17936375
D002087Butyrates2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Butyrates results in increased expression of and affects the localization of CFTR protein]15304546
D002087ButyratesButyrates inhibits the reaction [CFTR protein binds to HSPA8 protein]15304546
D002087ButyratesButyrates inhibits the reaction [CFTR protein mutant form binds to HSPA8 protein]15304546
D002087ButyratesButyrates results in increased expression of and affects the localization of and results in increased stability of CFTR protein15304546
D002087ButyratesButyrates results in increased expression of CFTR mRNA mutant form17541014
D002087ButyratesButyrates results in increased expression of CFTR protein mutant form17541014
D002104Cadmiumalpha-Tocopherol inhibits the reaction [Cadmium results in decreased expression of CFTR protein]20363832
D002104CadmiumCadmium results in decreased expression of CFTR mRNA21120746
D002104CadmiumCadmium results in decreased expression of CFTR protein20363832
D002104Cadmium[Cadmium results in decreased expression of CFTR protein] which results in decreased transport of Chlorides20363832
D002104CadmiumCadmium results in decreased expression of CFTR protein20363832
D002118CalciumCFTR protein mutant form affects the transport of Calcium22514656
D002118Calcium[[denufosol tetrasodium affects the activity of P2RY2 protein] which results in increased secretion of Calcium] affects the reaction [CFTR protein mutant form affects the transport of Calcium]22514656
D002118Calciumdenufosol tetrasodium inhibits the reaction [CFTR protein mutant form affects the transport of Calcium]22514656
D002211CapsaicinCapsaicin results in increased activity of CFTR protein15155835
D002211CapsaicinCapsaicin results in increased activity of CFTR protein mutant form15155835
D002330CarmustineCarmustine affects the activity of CFTR protein mutant form17849169
D002330CarmustineCarmustine promotes the reaction [Dithiothreitol affects the activity of CFTR protein mutant form]17849169
D002330CarmustineCarmustine promotes the reaction [Mercaptoethanol affects the activity of CFTR protein mutant form]17849169
C033394CGP 121772-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C033394CGP 121772-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C033394CGP 12177CGP 12177 results in increased activity of CFTR protein15563584
C033394CGP 12177Pertussis Toxin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C033394CGP 12177U 0126 inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C033394CGP 12177wortmannin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C016299chelerythrinechelerythrine results in decreased activity of CFTR protein14744818
D002712ChloridesCFTR protein affects the transport of Chlorides8886418
D002712ChloridesArsenic inhibits the reaction [CFTR protein results in increased secretion of Chlorides]17038445
D002712ChloridesCFTR protein results in increased secretion of Chlorides16791002|2020702
D002712Chloridessodium arsenite inhibits the reaction [CFTR protein results in increased secretion of Chlorides]16791002|2020702
D002712Chlorides1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D002712Chlorides3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Adenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
D002712Chlorides3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [CFTR protein results in increased export of Chlorides]20675434
D002712Chlorides3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
D002712Chlorides"7,8-benzoquinoline promotes the reaction [CFTR protein affects the secretion of Chlorides]"12967937
D002712ChloridesAdenosine Triphosphate promotes the reaction [CFTR protein results in increased export of Chlorides]20675434
D002712ChloridesAscorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides]14993613
D002712Chlorides[Cadmium results in decreased expression of CFTR protein] which results in decreased transport of Chlorides20363832
D002712ChloridesCFTR protein affects the export of Chlorides12914781
D002712ChloridesCFTR protein affects the secretion of Chlorides12714375|1296793
D002712ChloridesCFTR protein affects the transport of Chlorides15148241|1521305
D002712ChloridesCFTR protein mutant form affects the transport of Chlorides1718974
D002712ChloridesCFTR protein mutant form results in decreased secretion of Chlorides15517342
D002712ChloridesCFTR protein mutant form results in decreased transport of Chlorides14993613
D002712ChloridesCFTR protein results in increased secretion of Chlorides14993613|1612103
D002712ChloridesCFTR protein results in increased transport of Chlorides11786964|1623682
D002712Chloridescilostazol promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712ChloridesColforsin promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D002712ChloridesCyclic AMP promotes the reaction [CFTR protein results in increased transport of Chlorides]11786964
D002712ChloridesGenistein promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D002712Chlorides[ivacaftor results in increased activity of CFTR protein mutant form] which results in increased secretion of Chlorides19846789
D002712ChloridesMethacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]20675434
D002712ChloridesMilrinone promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712ChloridesPapaverine promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712ChloridesPhosphodiesterase Inhibitors promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712ChloridesRolipram promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712ChloridesSildenafil Citrate promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D002712Chloridessodium arsenite inhibits the reaction [CFTR protein results in increased secretion of Chlorides]16121039
D002712ChloridesBrimonidine Tartrate inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D002712ChloridesCFTR protein affects the transport of Chlorides12598592|1467919
D002712ChloridesCFTR protein mutant form results in decreased transport of Chlorides15650130
D002712ChloridesClonidine inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D002712ChloridesGlyburide inhibits the reaction [CFTR protein affects the transport of Chlorides]15650130
D002712ChloridesMedetomidine inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D002712Chlorides[Gentamicins results in increased expression of and results in increased activity of CFTR protein mutant form] which results in increased export of Chlorides17290305
D002712ChloridesCFTR protein results in increased secretion of Chlorides16432888
D002712Chlorides[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]16236827
D002712ChloridesMercuric Chloride inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]]16236827
D002712ChloridesCFTR protein affects the transport of Chlorides12172647|1526569
D002712ChloridesCFTR protein results in increased transport of Chlorides8397274
D002713ChlorineCFTR protein results in increased transport of Chlorine21765217
D002713ChlorineCFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]12612912
D002713ChlorineNitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]12612912
D0027314-Chloromercuribenzenesulfonate4-Chloromercuribenzenesulfonate results in decreased activity of CFTR protein16236827
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of CFTR mRNA26272509
D002746ChlorpromazineChlorpromazine results in decreased secretion of CFTR protein mutant form17936375
D002772Cholera ToxinCholera Toxin results in increased activity of CFTR protein15872007
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA20938992
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of CFTR mRNA28472532
C045645cilostazolcilostazol promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
C045645cilostazolcilostazol results in increased activity of CFTR protein12714375
D002994ClofibrateClofibrate results in increased expression of CFTR mRNA17585979
D003000ClonidineClonidine inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D005576ColforsinColforsin results in increased activity of CFTR protein15140627
D005576Colforsin[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein16027156
D005576Colforsin[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form15163550
D005576Colforsin3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D005576Colforsin"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]"16038730
D005576Colforsin[5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride co-treated with Colforsin] results in increased activity of CFTR protein mutant form15163550
D005576Colforsin5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D005576Colforsin5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D005576Colforsin6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D005576Colforsinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576Colforsinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinBrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinBrefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinCFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]18230692
D005576ColforsinColforsin affects the localization of CFTR protein15994425
D005576ColforsinColforsin analog results in increased activity of CFTR protein mutant form22074181
D005576ColforsinColforsin binds to and results in decreased activity of CFTR protein15194485
D005576Colforsin[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein15763242
D005576Colforsin[Colforsin co-treated with Genistein] results in increased activity of CFTR protein18230692
D005576Colforsin[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides18230692
D005576Colforsin[Colforsin co-treated with NS 004] results in increased activity of CFTR protein mutant form14502435
D005576ColforsinColforsin promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D005576ColforsinColforsin results in increased activity of CFTR protein12914781|1496773
D005576ColforsinColforsin results in increased activity of CFTR protein mutant form21724857
D005576ColforsinColforsin results in increased phosphorylation of and results in increased activity of CFTR protein21724857
D005576Colforsinfenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D005576Colforsinfenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]16038730
D005576Colforsingeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576Colforsingeldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinGlyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D005576ColforsinGlyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]14967738|1906187
D005576Colforsinmiglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D005576ColforsinN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]14967738
D005576ColforsinN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]21724857
D005576ColforsinOzone inhibits the reaction [Colforsin results in increased activity of CFTR protein]19061877
D005576ColforsinThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinThapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D005576ColforsinVRT 532 analog promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]22074181
D005576ColforsinVRT 532 promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]21724857
D005576Colforsin[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein15517342
D005576ColforsinColforsin results in increased activity of CFTR protein15246976|1579091
D005576ColforsinColforsin results in increased activity of CFTR protein15140627
D005576ColforsinAICA ribonucleotide inhibits the reaction [Colforsin results in increased activity of CFTR protein]12519745
D005576Colforsin[Colforsin co-treated with Genistein] results in increased activity of CFTR protein17596272
D005576ColforsinColforsin results in increased activity of CFTR protein12519745|1538955
D005576Colforsin[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]16236827
D005576ColforsinMercuric Chloride inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]]16236827
D005576ColforsinColforsin results in increased activity of CFTR protein15246976
D005576ColforsinColforsin results in increased phosphorylation of and results in increased activity of CFTR protein25946147
D003471CuprizoneCuprizone results in decreased expression of CFTR mRNA26577399
D003474CurcuminAdenosine Triphosphate affects the reaction [Curcumin results in increased activity of CFTR protein mutant form]17178710
D003474CurcuminCurcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]23978416
D003474CurcuminCurcumin results in increased activity of CFTR protein15582996|1717871
D003474CurcuminCurcumin results in increased activity of CFTR protein mutant form15582996
D003474Curcumin[PRKCA protein results in increased phosphorylation of CFTR protein] promotes the reaction [Curcumin results in increased activity of CFTR protein]17178710
D003474CurcuminCurcumin affects the folding of and affects the localization of CFTR protein mutant form15280357
D003474CurcuminCurcumin affects the localization of CFTR protein mutant form15105504
D003513CycloheximideCycloheximide affects the expression of CFTR mRNA17290305
D016572CyclosporineCyclosporine results in decreased methylation of CFTR promoter27989131
D003634DDTDDT inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]14766015
D003634DDTDDT results in decreased expression of CFTR protein22426039
D003894Deamino Arginine VasopressinDeamino Arginine Vasopressin results in increased activity of CFTR protein15685210
C465279denufosol tetrasodium[[denufosol tetrasodium affects the activity of P2RY2 protein] which results in increased secretion of Calcium] affects the reaction [CFTR protein mutant form affects the transport of Calcium]22514656
C465279denufosol tetrasodiumdenufosol tetrasodium inhibits the reaction [CFTR protein mutant form affects the transport of Calcium]22514656
D003958Diamide[Glutathione co-treated with Diamide] results in decreased activity of CFTR protein15857825
D004004DichlororibofuranosylbenzimidazoleDichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
D004054DiethylstilbestrolDiethylstilbestrol results in decreased activity of CFTR protein10991979
D004054DiethylstilbestrolDiethylstilbestrol results in increased expression of CFTR mRNA15289156
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]"16038730
D0178784,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid"4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid results in decreased activity of CFTR protein"15131065
D004229DithiothreitolDithiothreitol inhibits the reaction [Glutathione results in decreased activity of CFTR protein]15657297
D004229DithiothreitolDithiothreitol inhibits the reaction [Mercuric Chloride results in decreased activity of CFTR protein]16236827
D004229DithiothreitolDithiothreitol inhibits the reaction [Mercury results in decreased activity of CFTR protein]16236827
D004229DithiothreitolCarmustine promotes the reaction [Dithiothreitol affects the activity of CFTR protein mutant form]17849169
D004317DoxorubicinDoxorubicin results in decreased ubiquitination of CFTR protein mutant form17762173
D004317DoxorubicinDoxorubicin results in increased folding of CFTR protein mutant form17762173
D004573ElectrolytesCFTR protein mutant form results in increased import of Electrolytes15517342
C017435enilconazoleenilconazole binds to CFTR protein29106682
C017435enilconazoleenilconazole results in decreased expression of CFTR mRNA29106682
C017435enilconazoleenilconazole results in decreased expression of CFTR protein29106682
D004768EnterotoxinsEnterotoxins results in increased activity of CFTR protein15049831
D004768Enterotoxins3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Enterotoxins results in increased activity of CFTR protein]14762788
D004768Enterotoxins3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Enterotoxins results in increased activity of CFTR protein]14762788
D004768EnterotoxinsEnterotoxins affects the localization of CFTR protein15872007
D004768EnterotoxinsEnterotoxins results in increased activity of CFTR protein15872007
C514340estradiol-17-benzoate[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR mRNA26529183
C514340estradiol-17-benzoate[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR protein26529183
C514340estradiol-17-benzoate[Genistein co-treated with estradiol-17-benzoate] results in increased expression of CFTR mRNA26529183
C514340estradiol-17-benzoate[Genistein co-treated with estradiol-17-benzoate] results in increased expression of CFTR protein26529183
D004967EstrogensEstrogens results in increased expression of and results in increased activity of CFTR protein16051669
D004967EstrogensEstrogens results in increased expression of CFTR mRNA16051669
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CFTR mRNA17555576|1794274
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CFTR mRNA17942748
D005033EthylmaleimideEthylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein]15657297
D005227Fatty AcidsCFTR protein mutant form affects the expression of and affects the metabolism of Fatty Acids14762183
D015736FelodipineFelodipine results in increased activity of CFTR protein mutant form21568323
C001209fenamic acidfenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
C001209fenamic acidfenamic acid inhibits the reaction [Colforsin results in increased activity of CFTR protein]16038730
C001209fenamic acidfenamic acid results in decreased activity of CFTR protein14502435|1466813
C001209fenamic acidfenamic acid results in decreased activity of CFTR protein15986093
C001209fenamic acidfenamic acid results in decreased activity of CFTR protein15020588
C001209fenamic acidfenamic acid results in decreased activity of CFTR protein15711774
C001209fenamic acidfenamic acid binds to and results in decreased activity of CFTR protein8397274
D005439Flufenamic AcidFlufenamic Acid results in decreased activity of CFTR protein15277574
D005439Flufenamic AcidFlufenamic Acid binds to and results in decreased activity of CFTR protein8397274
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA20938992
C039281furanfuran results in increased expression of CFTR mRNA26194646|2738771
C001277geldanamycingeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C001277geldanamycingeldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C001277geldanamycingeldanamycin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C001277geldanamycingeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
D015248GemfibrozilGemfibrozil results in decreased activity of CFTR protein15289377
D019833GenisteinGenistein results in decreased activity of CFTR protein15496164
D019833Genistein3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D019833Genistein5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D019833Genistein5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D019833Genistein6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D019833Genisteinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833Genisteinbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinBrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinBrefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinCFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]18230692
D019833Genistein[Colforsin co-treated with Genistein] results in increased activity of CFTR protein18230692
D019833Genistein[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides18230692
D019833Genisteinfenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D019833Genisteingeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833Genisteingeldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinGenistein affects the localization of CFTR protein mutant form15191910
D019833GenisteinGenistein promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D019833GenisteinGenistein results in increased activity of CFTR protein12914781|1516355
D019833GenisteinGenistein results in increased activity of CFTR protein mutant form15163550
D019833GenisteinGlyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D019833Genisteinmiglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D019833GenisteinThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinThapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019833GenisteinGenistein promotes the reaction [Cyclic AMP results in increased activity of CFTR protein mutant form]12556293
D019833GenisteinGenistein results in increased activity of CFTR protein15155835
D019833GenisteinGenistein results in increased activity of CFTR protein mutant form15155835
D019833GenisteinGenistein results in increased expression of CFTR mRNA15289156
D019833Genistein[Colforsin co-treated with Genistein] results in increased activity of CFTR protein17596272
D019833Genistein[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR mRNA26529183
D019833Genistein[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR protein26529183
D019833Genistein[Genistein co-treated with estradiol-17-benzoate] results in increased expression of CFTR mRNA26529183
D019833Genistein[Genistein co-treated with estradiol-17-benzoate] results in increased expression of CFTR protein26529183
D019833GenisteinGenistein affects the localization of CFTR protein15925323
D019833GenisteinGenistein promotes the reaction [5-nitro-2-(3-phenylpropylamino)benzoic acid results in decreased activity of CFTR protein]15925323
D019833GenisteinGenistein results in increased activity of CFTR protein15996659|2594614
D005839GentamicinsGentamicins results in increased activity of CFTR protein mutant form11786964|1453433
D005839GentamicinsGentamicins results in increased expression of and results in increased activity of CFTR protein mutant form11401894
D005839GentamicinsGentamicins results in increased expression of and results in increased activity of CFTR protein mutant form17290305
D005839Gentamicins[Gentamicins results in increased expression of and results in increased activity of CFTR protein mutant form] which results in increased export of Chlorides17290305
D005978GlutathioneDithiothreitol inhibits the reaction [Glutathione results in decreased activity of CFTR protein]15657297
D005978GlutathioneEthylmaleimide inhibits the reaction [Glutathione results in decreased activity of CFTR protein]15657297
D005978GlutathioneGlutathione analog results in decreased activity of CFTR protein15657297
D005978Glutathione[Glutathione co-treated with Diamide] results in decreased activity of CFTR protein15857825
D005978GlutathioneCFTR protein affects the export of Glutathione15561710
D005978GlutathioneCFTR protein affects the export of Glutathione15845416
D019803Glutathione DisulfideGlutathione Disulfide results in decreased activity of CFTR protein15657297
D005905GlyburideGlyburide results in decreased activity of CFTR protein15371258
D005905GlyburideGlyburide results in decreased activity of CFTR protein15496164
D005905GlyburideGlyburide results in decreased activity of CFTR protein15365090
D005905GlyburideGlyburide binds to and results in decreased activity of CFTR protein15857825
D005905GlyburideGlyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]14967738
D005905GlyburideGlyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D005905GlyburideGlyburide inhibits the reaction [Colforsin results in increased activity of CFTR protein]14967738|1906187
D005905GlyburideGlyburide results in decreased activity of CFTR protein14502435|1513106
D005905GlyburideGlyburide inhibits the reaction [CFTR protein affects the transport of Bicarbonates]15650130
D005905GlyburideGlyburide inhibits the reaction [CFTR protein affects the transport of Chlorides]15650130
D005905GlyburideGlyburide results in decreased activity of CFTR protein15650130|1601294
D005905GlyburideGlyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein]17596272
D005905GlyburideGlyburide results in decreased activity of CFTR protein15236628|1538955
D005905GlyburideGlyburide binds to and affects the folding of and results in decreased activity of CFTR protein15366420
D005905GlyburideGlyburide binds to and results in decreased activity of CFTR protein15711774
D005905GlyburideGlyburide results in decreased activity of CFTR protein15235914
D005905GlyburideGlyburide results in decreased activity of CFTR protein15306545
C004312glycidolglycidol results in decreased expression of CFTR mRNA24915197
D018684Glycine AgentsGlycine Agents analog results in increased activity of CFTR protein mutant form15722457
D006062GonadotropinsGonadotropins results in increased expression of and results in increased activity of CFTR protein16051669
D006062GonadotropinsGonadotropins results in increased expression of CFTR mRNA16051669
C072685guanylinguanylin results in increased phosphorylation of CFTR protein14986129
C037258gusperimus[ALB protein binds to gusperimus] which results in increased activity of CFTR protein mutant form18515409
D019850HeptanolHeptanol results in increased activity of CFTR protein14967738
C088350hexestrol diazirinehexestrol diazirine binds to CFTR protein10991979
C088350hexestrol diazirinehexestrol diazirine results in decreased activity of CFTR protein10991979
D012701SerotoninSerotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein]15151902
D012701SerotoninSerotonin results in increased activity of CFTR protein15151902
D006820Hyaluronic AcidCFTR protein results in increased export of Hyaluronic Acid23978416
D006820Hyaluronic AcidCurcumin analog inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]23978416
D006820Hyaluronic Acidxanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]23978416
D006854HydrocortisoneHydrocortisone results in increased expression of CFTR mRNA17038445
D006854HydrocortisoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of CFTR mRNA]17038445
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of CFTR mRNA20044591
D007454Iodides3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D007454Iodides5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D007454Iodides5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D007454Iodides6-hydroxy-10-chlorobenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D007454Iodidesbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454Iodidesbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454IodidesBrefeldin A inhibits the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454IodidesBrefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454IodidesCFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]18230692
D007454Iodides[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides18230692
D007454Iodidesfenamic acid inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D007454Iodidesgeldanamycin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454Iodidesgeldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454IodidesGlyburide inhibits the reaction [[[Colforsin co-treated with Genistein] results in increased activity of CFTR protein] which results in increased transport of Iodides]18230692
D007454Iodidesmiglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
D007454IodidesThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D007454IodidesThapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D015759IonomycinIonomycin results in increased activity of CFTR protein15389550
C051890irinotecanirinotecan affects the expression of CFTR mRNA20097248
D0150561-Methyl-3-isobutylxanthine"[1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein"15161604
D0150561-Methyl-3-isobutylxanthine"[1-Methyl-3-isobutylxanthine co-treated with 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] results in increased activity of CFTR protein mutant form"15163550
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein16027156
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein mutant form15163550
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the export of Chlorides]12914781
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine results in increased activity of CFTR protein12914781
D0150561-Methyl-3-isobutylxanthine[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] results in increased activity of CFTR protein15763242
D0150561-Methyl-3-isobutylxanthine[1-Methyl-3-isobutylxanthine co-treated with Colforsin] results in increased activity of CFTR protein15517342
D0150561-Methyl-3-isobutylxanthine1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water]12606488
D0150561-Methyl-3-isobutylxanthine[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]16236827
D0150561-Methyl-3-isobutylxanthineMercuric Chloride inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]]16236827
D014668VasotocinVasotocin results in increased activity of CFTR protein15685210
D007545IsoproterenolBaclofen promotes the reaction [Isoproterenol results in increased activity of CFTR protein]15151902
D007545Isoproterenol"Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]"15151902
D007545Isoproterenol[Isoproterenol co-treated with Adenosine] results in increased activity of CFTR protein15039139
D007545IsoproterenolIsoproterenol results in increased activity of CFTR protein15039139|1515190
D007545IsoproterenolSerotonin promotes the reaction [Isoproterenol results in increased activity of CFTR protein]15151902
D007545IsoproterenolIsoproterenol results in increased activity of CFTR protein15020588
C008215isotocinisotocin results in increased activity of CFTR protein15685210
C545203ivacaftorivacaftor results in increased activity of CFTR protein21083385
C545203ivacaftorivacaftor results in increased activity of CFTR protein mutant form19846789|2108338
C545203ivacaftor[ivacaftor results in increased activity of CFTR protein mutant form] which affects the transport of Sodium19846789
C545203ivacaftor[ivacaftor results in increased activity of CFTR protein mutant form] which results in increased secretion of Chlorides19846789
C006552kaempferolkaempferol affects the localization of CFTR protein mutant form15191910
C459562L-826,141"L-826,141 results in increased activity of CFTR protein"15901792
D016308Enkephalin, Leucine-2-Alanine"Enkephalin, Leucine-2-Alanine promotes the reaction [Isoproterenol results in increased activity of CFTR protein]"15151902
D008070LipopolysaccharidesLipopolysaccharides binds to CFTR protein14688350
D018021Lithium ChlorideLithium Chloride results in increased expression of CFTR mRNA23527032
C016371lonidaminelonidamine results in decreased activity of CFTR protein15634668
C016371lonidaminelonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
C016371lonidaminelonidamine results in decreased activity of CFTR protein12606488
D020926MedetomidineMedetomidine inhibits the reaction [CFTR protein affects the transport of Chlorides]12598592
D008623MercaptoethanolCarmustine promotes the reaction [Mercaptoethanol affects the activity of CFTR protein mutant form]17849169
C042720mercuric bromidemercuric bromide results in increased expression of CFTR mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
D008627Mercuric ChlorideDithiothreitol inhibits the reaction [Mercuric Chloride results in decreased activity of CFTR protein]16236827
D008627Mercuric ChlorideMercuric Chloride inhibits the reaction [[Colforsin co-treated with 1-Methyl-3-isobutylxanthine] promotes the reaction [CFTR protein results in increased transport of Chlorides]]16236827
D008627Mercuric ChlorideMercuric Chloride results in decreased activity of CFTR protein16236827|1643288
D008628MercuryDithiothreitol inhibits the reaction [Mercury results in decreased activity of CFTR protein]16236827
D008628MercuryMercury results in decreased activity of CFTR protein16236827|1643288
D016210Methacholine Chloride3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [Methacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]]20675434
D016210Methacholine ChlorideMethacholine Chloride promotes the reaction [CFTR protein results in increased export of Chlorides]20675434
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CFTR mRNA20938992
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CFTR mRNA26011545
D015735MifepristoneMifepristone inhibits the reaction [Hydrocortisone results in increased expression of CFTR mRNA]17038445
C059896miglustatbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C059896miglustatbenzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C059896miglustatBrefeldin A inhibits the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C059896miglustatBrefeldin A inhibits the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C059896miglustatgeldanamycin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C059896miglustatgeldanamycin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C059896miglustatmiglustat inhibits the reaction [CANX protein binds to CFTR protein mutant form]18230692
C059896miglustatmiglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]18230692
C059896miglustatmiglustat results in increased activity of CFTR protein mutant form18230692
C059896miglustatThapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
C059896miglustatThapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C059896miglustatmiglustat affects the localization of and affects the glycosylation of CFTR protein mutant form18230692
C059896miglustatmiglustat affects the localization of CFTR protein mutant form19299496
D020105MilrinoneMilrinone promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D020105MilrinoneMilrinone results in increased activity of CFTR protein12714375
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide affects the localization of CFTR protein15994425
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]14967738
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased activity of CFTR protein]14967738
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in increased phosphorylation of CFTR protein]21724857
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide results in decreased activity of CFTR protein14744818
C063509N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamideN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]12606488
C548779N-(2-naphthalenyl)-((3,5-dibromo-2,4-dihydroxyphenyl)methylene)glycine hydrazide"N-(2-naphthalenyl)-((3,5-dibromo-2,4-dihydroxyphenyl)methylene)glycine hydrazide results in decreased activity of CFTR protein"21707078
C064769N-acetylsphingosineN-acetylsphingosine results in increased activity of CFTR protein15474513
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of CFTR mRNA"25511174
C031721naphthaleneCFTR gene mutant form affects the reaction [naphthalene results in decreased expression of ALDH1A1 protein]19438287
C031721naphthaleneCFTR gene mutant form affects the reaction [naphthalene results in decreased expression of ALDH2 protein]19438287
C031721naphthaleneCFTR gene mutant form affects the reaction [naphthalene results in decreased expression of CBR2 protein]19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ACO2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ALDH1A1 mRNA19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ALDH1A1 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ALDH2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of ATP5A1 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CAP1 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CBR2 mRNA19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CBR2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CCT1 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CCT2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of CCT5 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of DPYSL2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of EEF2 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of EHD4 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of EZR protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of KRT16 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of LDHB protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of LMNA protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of MSN protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of PKM protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of RDX protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of SEC14L3 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of SELENBP1 protein19438287
C031721naphthalene[naphthalene co-treated with CFTR gene mutant form] results in decreased expression of VAT1 protein19438287
C029383n-decyl alcoholn-decyl alcohol results in increased activity of CFTR protein14967738
D009532NickelNickel results in decreased expression of CFTR mRNA24768652|2558310
D009543NifedipineNifedipine results in increased activity of CFTR protein mutant form21568323
D009544Niflumic AcidNiflumic Acid results in decreased activity of CFTR protein14668136
D009566NitratesNitrates results in decreased activity of CFTR protein15286085
D009569Nitric OxideNitric Oxide inhibits the reaction [CFTR protein promotes the reaction [Cyclic AMP results in increased transport of Chlorine]]12612912
D026422S-Nitrosoglutathioneacivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]14766015
D026422S-Nitrosoglutathioneacivicin inhibits the reaction [S-Nitrosoglutathione results in increased expression of CFTR mRNA]14766015
D026422S-NitrosoglutathioneDDT inhibits the reaction [S-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein]14766015
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in decreased activity of CFTR protein15657297
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in decreased expression of CFTR mRNA14766015
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in increased expression of and results in increased stability of CFTR protein14766015
D026422S-NitrosoglutathioneS-Nitrosoglutathione results in increased expression of CFTR mRNA14766015
D015739NocodazoleNocodazole affects the localization of CFTR protein15994425
D015739NocodazoleNocodazole inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]12529251
C083230NS 004[Colforsin co-treated with NS 004] results in increased activity of CFTR protein mutant form14502435
C083230NS 004NS 004 results in increased activity of CFTR protein14502435
D0200031-Octanol1-Octanol results in increased activity of CFTR protein14967738
D0200031-Octanol1-Octanol results in increased activity of CFTR protein mutant form14967738
D0200031-OctanolGlyburide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]14967738
D0200031-OctanolN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [1-Octanol results in increased activity of CFTR protein]14967738
D019319Okadaic AcidOkadaic Acid results in decreased activity of CFTR protein15936019
D009853OmeprazoleCFTR protein affects the metabolism of Omeprazole15319328
D010126OzoneAcetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]19061877
D010126OzoneAcetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein]19061877
D010126Ozone"alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]"19061877
D010126OzoneOzone inhibits the reaction [Colforsin results in increased activity of CFTR protein]19061877
D010126OzoneOzone results in decreased expression of CFTR mRNA19061877
D010126OzoneOzone results in decreased expression of CFTR protein19061877
D010126OzoneOzone results in increased expression of CFTR mRNA27206323
D010126Ozonepimagedine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]19061877
D010126Ozonepimagedine inhibits the reaction [Ozone results in decreased expression of CFTR protein]19061877
C012275P(1),P(5)-di(adenosine-5'-)pentaphosphate"P(1),P(5)-di(adenosine-5'-)pentaphosphate inhibits the reaction [Adenosine Diphosphate binds to and results in decreased activity of CFTR protein]"15684079
C112653PAPA NONOatePAPA NONOate affects the localization of CFTR protein15994425
D010208PapaverinePapaverine promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D010208PapaverinePapaverine results in increased activity of CFTR protein12714375
D010269ParaquatParaquat affects the splicing of CFTR exon27111068
D010269ParaquatParaquat affects the expression of CFTR mRNA15206577
D037342Pertussis ToxinPertussis Toxin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
D010656PhenylephrineGlyburide inhibits the reaction [[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein]17596272
D010656Phenylephrine[Phenylephrine co-treated with 5-butyl-6-hydroxy-10-chlorobenzo(c)quinolizinium chloride] results in increased activity of CFTR protein17596272
D010656Phenylephrine[Phenylephrine co-treated with 6-hydroxy-10-chlorobenzo(c)quinolizinium] results in increased activity of CFTR protein17596272
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of CFTR mRNA26272509
D010693PhloretinPhloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
C119222phorbol-12-myristatephorbol-12-myristate results in increased activity of CFTR protein15229107
C119222phorbol-12-myristatephorbol-12-myristate results in increased activity of CFTR protein15229107
D010712Phosphatidic AcidsPhosphatidic Acids inhibits the reaction [1-Butanol results in decreased expression of and results in decreased secretion of CFTR protein]17936375
D010712Phosphatidic AcidsPhosphatidic Acids results in decreased transport of CFTR protein17936375
D010712Phosphatidic AcidsPhosphatidic Acids results in decreased transport of CFTR protein mutant form17936375
D010716PhosphatidylinositolsPhosphatidylinositols results in increased activity of CFTR protein14710196
D010726Phosphodiesterase InhibitorsPhosphodiesterase Inhibitors promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D010726Phosphodiesterase InhibitorsPhosphodiesterase Inhibitors results in increased activity of CFTR protein12714375
C030090phosphoramide mustardphosphoramide mustard results in increased expression of CFTR mRNA27888070
C004479pimagedinepimagedine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]19061877
C004479pimagedinepimagedine inhibits the reaction [Ozone results in decreased expression of CFTR protein]19061877
D010936Plant ExtractsPlant Extracts results in decreased expression of CFTR mRNA23557933
D011319PrimaquinePrimaquine inhibits the reaction [Cyclic AMP affects the localization of and results in increased activity of CFTR protein]12529251
D011374Progesterone[Progesterone co-treated with Estradiol] results in decreased expression of CFTR mRNA17404688
D011374ProgesteroneProgesterone results in decreased expression of CFTR mRNA15471937
D011374ProgesteroneProgesterone results in decreased expression of CFTR protein15471937
D011374Progesterone[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR mRNA26529183
D011374Progesterone[Genistein co-treated with estradiol-17-benzoate co-treated with Progesterone] results in increased expression of CFTR protein26529183
D011433PropranololPropranolol results in decreased secretion of CFTR protein mutant form17936375
D011441PropylthiouracilPropylthiouracil affects the expression of CFTR mRNA24780913
D011453ProstaglandinsProstaglandins results in increased activity of CFTR protein16055675
D019269Phosphatidylinositol 4,5-Diphosphate"[Phosphatidylinositol 4,5-Diphosphate co-treated with Adenosine Triphosphate] results in increased activity of CFTR protein"14710196
D019269Phosphatidylinositol 4,5-Diphosphate"Phosphatidylinositol 4,5-Diphosphate results in increased activity of CFTR protein"14710196
D011794QuercetinQuercetin results in increased activity of CFTR protein mutant form15191910
D011794QuercetinQuercetin results in increased expression of CFTR mRNA28431985
D011794QuercetinQuercetin results in increased expression of CFTR protein28431985
C082134relcovaptanrelcovaptan results in decreased activity of CFTR protein15685210
C059514resveratrolresveratrol results in increased activity of CFTR protein24282612|2594614
C059514resveratrolresveratrol results in increased activity of CFTR protein24282612
C059514resveratrolresveratrol results in increased activity of CFTR protein24282612
C059514resveratrol3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [resveratrol results in increased activity of CFTR protein]24147347
C059514resveratrolresveratrol results in increased activity of CFTR protein24147347|2438023
C014925RMI 12330ARMI 12330A inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
D020889RolipramRolipram promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D020889RolipramRolipram results in decreased activity of CFTR protein15611099
D020889RolipramRolipram results in increased activity of CFTR protein12714375
D000068299Salmeterol Xinafoate[Salmeterol Xinafoate binds to ADRB2 protein] which results in increased expression of CFTR protein12621035
D000068299Salmeterol XinafoateSalmeterol Xinafoate promotes the reaction [CFTR protein binds to SLC9A3R1 protein]12621035
D000068299Salmeterol XinafoateSalmeterol Xinafoate results in increased expression of CFTR protein12621035
D012492SaltsCFTR protein affects the transport of Salts15657297
D012604Scorpion VenomsScorpion Venoms results in decreased activity of CFTR protein15240343
D000068677Sildenafil CitrateSildenafil Citrate affects the localization of CFTR protein mutant form15618584
D000068677Sildenafil CitrateSildenafil Citrate promotes the reaction [CFTR protein affects the secretion of Chlorides]12714375
D000068677Sildenafil CitrateSildenafil Citrate results in increased activity of CFTR protein12714375
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CFTR mRNA25895662
D012964Sodium[ivacaftor results in increased activity of CFTR protein mutant form] which affects the transport of Sodium19846789
D012964SodiumCFTR protein affects the transport of Sodium22442149
C017947sodium arsenitesodium arsenite inhibits the reaction [CFTR protein results in increased secretion of Chlorides]16791002|2020702
C017947sodium arsenitesodium arsenite inhibits the reaction [SGK1 protein results in increased activity of CFTR protein]20207026
C017947sodium arsenitesodium arsenite results in decreased expression of and affects the localization of CFTR protein20207026
C017947sodium arsenitesodium arsenite results in increased ubiquitination of and results in increased degradation of CFTR protein20207026
C017947sodium arseniteDichlororibofuranosylbenzimidazole inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
C017947sodium arsenitesodium arsenite inhibits the reaction [CFTR protein results in increased secretion of Chlorides]16121039
C017947sodium arsenitesodium arsenite results in decreased expression of CFTR protein16121039
C017947sodium arsenitesodium arsenite results in increased expression of CFTR mRNA26535918
C017947sodium arsenite[U 0126 results in decreased activity of MAPK1 protein] inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
C017947sodium arsenite[U 0126 results in decreased activity of MAPK3 protein] inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
C009279sodium bisulfite[Bicarbonates co-treated with sodium bisulfite] results in increased phosphorylation of CFTR protein12519749
C009279sodium bisulfitesodium bisulfite results in increased phosphorylation of CFTR protein12519749
D012974Sodium IodideCFTR protein affects the export of Sodium Iodide14502435
D053260SootSoot results in increased expression of CFTR mRNA22461453
C080461SP 303SP 303 results in decreased activity of CFTR protein15517342
D013449SulfonamidesSulfonamides analog results in increased activity of CFTR protein mutant form15722457
D013629TamoxifenTamoxifen affects the expression of CFTR mRNA17555576
D013656Taurocholic AcidCFTR protein mutant form affects the uptake of Taurocholic Acid15099439
D013656Taurocholic AcidTaurocholic Acid results in increased activity of CFTR protein16037545
C066776taurolithocholic acid 3-sulfatetaurolithocholic acid 3-sulfate results in decreased activity of CFTR protein15634668
D013739Testosterone[bisphenol A co-treated with Testosterone] results in decreased expression of CFTR mRNA26496021
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CFTR mRNA19684285
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CFTR mRNA21570461|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CFTR mRNA17942748
C017953tetramethylpyrazine"1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]"15763242
C017953tetramethylpyrazine3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
C017953tetramethylpyrazineN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
C017953tetramethylpyrazineRMI 12330A inhibits the reaction [tetramethylpyrazine results in increased activity of CFTR protein]15763242
C017953tetramethylpyrazinetetramethylpyrazine results in increased activity of CFTR protein15763242
C017953tetramethylpyrazinetetramethylpyrazine results in increased activity of CFTR protein16015685
C017953tetramethylpyrazinetetramethylpyrazine results in increased activity of CFTR protein16015685
D019284ThapsigarginThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019284ThapsigarginThapsigargin promotes the reaction [5-butyl-7-chloro-6-hydroxybenzo(c)quinolizinium results in increased activity of CFTR protein mutant form]18230692
D019284ThapsigarginThapsigargin promotes the reaction [miglustat inhibits the reaction [CFTR protein mutant form inhibits the reaction [[Colforsin co-treated with Genistein] results in increased transport of Iodides]]]18230692
D019284ThapsigarginThapsigargin promotes the reaction [miglustat results in increased activity of CFTR protein mutant form]18230692
C031760thiocyanateCFTR protein affects the transport of thiocyanate15345749
D013890ThioureaThiourea results in decreased expression of CFTR mRNA15248066
C009495titanium dioxidetitanium dioxide results in increased expression of CFTR mRNA23557971
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of and results in decreased activity of CFTR protein16497995
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of CFTR mRNA16497995|2740439
D014028Tobacco Smoke PollutionTobacco Smoke Pollution affects the expression of CFTR mRNA20133372
C035964trequinsintrequinsin results in increased activity of CFTR protein15901792
D014212TretinoinTretinoin results in decreased expression of CFTR mRNA12834868
C012589trichostatin Atrichostatin A results in increased expression of CFTR mRNA24935251
D017973Tungsten CompoundsTungsten Compounds results in decreased expression of CFTR mRNA28666766
C113580U 0126U 0126 inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C113580U 0126[U 0126 results in decreased activity of MAPK1 protein] inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
C113580U 0126[U 0126 results in decreased activity of MAPK3 protein] inhibits the reaction [sodium arsenite results in decreased expression of CFTR protein]16121039
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CFTR mRNA"27188386
D014635Valproic AcidValproic Acid results in increased expression of CFTR mRNA23179753|2438349
D014635Valproic AcidValproic Acid affects the expression of CFTR mRNA17292431
D014638VanadatesVanadates results in increased activity of CFTR protein15240343
D014667VasopressinsVasopressins results in increased activity of CFTR protein15513933
C535089VRT 532VRT 532 affects the folding of CFTR protein mutant form22074181
C535089VRT 532VRT 532 analog promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]22074181
C535089VRT 532VRT 532 promotes the reaction [Colforsin results in increased activity of CFTR protein mutant form]21724857
C535089VRT 532VRT 532 results in increased activity of and affects the transport of CFTR protein mutant form22074181
C535089VRT 532VRT 532 results in increased activity of CFTR protein22074181
C535089VRT 532VRT 532 results in increased activity of CFTR protein mutant form21724857
D014867Water1-Methyl-3-isobutylxanthine promotes the reaction [CFTR protein affects the transport of Water]12606488
D014867WaterCFTR protein promotes the reaction [AQP9 protein affects the transport of Water]12606488
D014867Waterlonidamine inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D014867WaterN-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CFTR protein affects the transport of Water]12606488
D014867WaterPhloretin inhibits the reaction [CFTR protein promotes the reaction [AQP9 protein affects the transport of Water]]12606488
D014867WaterCFTR protein affects the transport of Water15657297
C009687wortmanninwortmannin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein]15563584
C104536xanthohumolxanthohumol inhibits the reaction [CFTR protein results in increased export of Hyaluronic Acid]23978416
D015032ZincZinc results in increased expression of CFTR mRNA16870260
D015032ZincZinc deficiency results in increased expression of CFTR mRNA19111725
D015032ZincZinc inhibits the reaction [Zinc deficiency results in increased expression of CFTR mRNA]19111725
D015032ZincZinc results in decreased activity of CFTR protein16236827
C016837zinc chloridezinc chloride results in increased expression of CFTR mRNA16870260

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005254chloride channel activity-IDA11524016  11707463  15010471  18570918  19019741  22178883  
GO:0005254chloride channel activity-IMP19621064  24885604  
GO:0005260intracellularly ATP-gated chloride channel activity-IMP8910473  
GO:0005260intracellularly ATP-gated chloride channel activity-NAS11707463  
GO:0005515protein binding-IPI9671706  9792704  11051556  11707463  12208510  12369822  
12471024  15247260  15936019  16203867  16546175  16901789  
17110338  17244609  18555783  19289574  19878303  20658517  
21884936  22038833  22121115  22178883  27092946  
GO:0005524ATP binding-IEA-  
GO:0015106bicarbonate transmembrane transporter activity-IDA15010471  19019741  
GO:0015106bicarbonate transmembrane transporter activity-ISS-  
GO:0015108chloride transmembrane transporter activity-ISS-  
GO:0015108chloride transmembrane transporter activity-TAS-  
GO:0016887ATPase activity-IDA8910473  11524016  
GO:0017081chloride channel regulator activity-TAS-  
GO:0019869chloride channel inhibitor activity-IDA22178883  
GO:0019899enzyme binding-IPI19398555  
GO:0030165PDZ domain binding-IDA11707463  
GO:0042626ATPase activity, coupled to transmembrane movement of substances-IBA21873635  
GO:0043225ATPase-coupled anion transmembrane transporter activity-TAS-  
GO:0051087chaperone binding-IPI16207813  
GO ID GO Term Qualifier Evidence PubMed
GO:0006695cholesterol biosynthetic process-IEA-  
GO:0006904vesicle docking involved in exocytosis-IEA-  
GO:0015701bicarbonate transport-IBA21873635  
GO:0015701bicarbonate transport-IDA15010471  19019741  
GO:0016579protein deubiquitination-TAS-  
GO:0030301cholesterol transport-IEA-  
GO:0035377transepithelial water transport-IMP19621064  
GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulus-IGI24885604  
GO:0035774positive regulation of insulin secretion involved in cellular response to glucose stimulus-IMP24885604  
GO:0045921positive regulation of exocytosis-IMP24885604  
GO:0048240sperm capacitation-ISS-  
GO:0050891multicellular organismal water homeostasis-IMP19621064  
GO:0051454intracellular pH elevation-ISS-  
GO:0055085transmembrane transport-IBA21873635  
GO:0055085transmembrane transport-TAS-  
GO:0060081membrane hyperpolarization-ISS-  
GO:0061024membrane organization-TAS-  
GO:0071320cellular response to cAMP-ISS-  
GO:0099133ATP hydrolysis coupled anion transmembrane transport-IEA-  
GO:1902161positive regulation of cyclic nucleotide-gated ion channel activity-IMP24885604  
GO:1902476chloride transmembrane transport-IBA21873635  
GO:1902476chloride transmembrane transport-IDA11524016  11707463  19019741  
GO:1902476chloride transmembrane transport-IMP19621064  24885604  
GO:1902943positive regulation of voltage-gated chloride channel activity-IDA22006324  
GO:1904322cellular response to forskolin-IDA15010471  19621064  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-ISS-  
GO:0005737cytoplasm-IDA18570918  
GO:0005765lysosomal membrane-TAS-  
GO:0005769early endosome-IDA19398555  
GO:0005789endoplasmic reticulum membrane-IDA11707463  
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0005829cytosol-IBA21873635  
GO:0005829cytosol-IDA24885604  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-IDA22178883  24885604  28130590  
GO:0005886plasma membrane-TAS-  
GO:0005887integral component of plasma membrane-IDA11524016  15010471  
GO:0005887integral component of plasma membrane-IMP11707463  
GO:0009986cell surface-IDA20658517  
GO:0010008endosome membrane-TAS-  
GO:0016020membrane-IBA21873635  
GO:0016021integral component of membrane-IDA8910473  
GO:0016324apical plasma membrane-IBA21873635  
GO:0016324apical plasma membrane-IDA12801959  15247260  18570918  20658517  28130590  
GO:0016324apical plasma membrane-IMP19621064  
GO:0030660Golgi-associated vesicle membrane-TAS-  
GO:0030665clathrin-coated vesicle membrane-TAS-  
GO:0031205endoplasmic reticulum Sec complexcolocalizes_withIDA9792704  
GO:0031901early endosome membrane-IEA-  
GO:0032991protein-containing complex-IDA17462998  
GO:0034707chloride channel complex-IEA-  
GO:0055037recycling endosome-IDA18570918  
GO:0055038recycling endosome membrane-IEA-  
KEGG ID KEGG Term
hsa02010ABC transporters
hsa04971Gastric acid secretion
hsa04972Pancreatic secretion
hsa04976Bile secretion
hsa05110Vibrio cholerae infection
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-1643685DiseaseTAS
R-HSA-194315Signaling by Rho GTPasesTAS
R-HSA-195258RHO GTPase EffectorsTAS
R-HSA-199991Membrane TraffickingTAS
R-HSA-382551Transport of small moleculesTAS
R-HSA-382556ABC-family proteins mediated transportTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-5619084ABC transporter disordersTAS
R-HSA-5619115Disorders of transmembrane transportersTAS
R-HSA-5627083RHO GTPases regulate CFTR traffickingTAS
R-HSA-5653656Vesicle-mediated transportTAS
R-HSA-5678895Defective CFTR causes cystic fibrosisTAS
R-HSA-5688426DeubiquitinationTAS
R-HSA-5689880Ub-specific processing proteasesTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-8856825Cargo recognition for clathrin-mediated endocytosisTAS
R-HSA-8856828Clathrin-mediated endocytosisTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
27115950Cystic Fibrosis Transmembrane Conductance Regulator. Implications in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. (2016 Apr)Cantin AMAnn Am Thorac Soc
18986377Association analyses of genetic polymorphisms of GSTM1, GSTT1, NQO1, NAT2, LPL, PRSS1, PSTI, and CFTR with chronic alcoholic pancreatitis in Japan. (2010 Feb)Maruyama KAlcohol Clin Exp Res
25447846Alcohol disrupts levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis. (2015 Feb)Maleth JGastroenterology
24755862Cigarette smoke and calcium conspire to impair CFTR function in airway epithelia. (2014)Braun APChannels (Austin)
25569187The Common Chymotrypsinogen C (CTRC) Variant G60G (C.180T) Increases Risk of Chronic Pancreatitis But Not Recurrent Acute Pancreatitis in a North American Population. (2015 Jan 8)LaRusch JClin Transl Gastroenterol
17212919[Oxidative stress, smoking and CFTR: can cystic fibrosis be acquired?]. (2007 Jan)Ouellet CMed Sci (Paris)
12503104A clinical perspective of cystic fibrosis and new genetic findings: relationship of CFTR mutations to genotype-phenotype manifestations. (2003 Jan 30)Kulczycki LLAm J Med Genet A
24106801Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis. (2014 Mar)Lambert JAAm J Respir Cell Mol Biol
9725921Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. (1998 Sep 3)Sharer NN Engl J Med
23538783Acquired cystic fibrosis transmembrane conductance regulator dysfunction in the lower airways in COPD. (2013 Aug)Dransfield MTChest
24040746Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function. (2013 Dec 1)Raju SVAm J Respir Crit Care Med
27585394The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke. (2017 Jan)Raju SVAm J Respir Cell Mol Biol
22768130A pharmacologic approach to acquired cystic fibrosis transmembrane conductance regulator dysfunction in smoking related lung disease. (2012)Sloane PAPLoS One
20597081Baseline characteristics and factors associated with nutritional and pulmonary status at enrollment in the cystic fibrosis EPIC observational cohort. (2010 Sep)Rosenfeld MPediatr Pulmonol
26857776Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Chronic Bronchitis and Other Diseases of Mucus Clearance. (2016 Mar)Raju SVClin Chest Med
23751316Clinical and morphological characteristics of sporadic genetically determined pancreatitis as compared to idiopathic pancreatitis: higher risk of pancreatic cancer in CFTR variants. (2013)Hamoir CDigestion
16111090Genetics of pancreatitis. (2005)Keim VScand J Surg
28874823Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells. (2017 Sep 5)Sailland JSci Rep
29251738NM23 proteins: innocent bystanders or local energy boosters for CFTR? (2018 Mar)Muimo RLab Invest
26856995CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis. (2016)Hegyi PRev Physiol Biochem Pharmacol
17079941Cigarette smoke-induced differential expression of the genes involved in exocrine function of the rat pancreas. (2006 Nov)Wittel UAPancreas
18953248Clinical and radiological outcome of patients suffering from chronic pancreatitis associated with gene mutations. (2008 Nov)Frulloni LPancreas
15645646Homozygous (TG)11 allele in intron 8 of the cystic fibrosis transmembrane conductance regulator (CFTR) gene has a protective role against bicarbonate decrease in pure pancreatic juice among Japanese male alcoholics. (2004 Dec)Nakamura YIntern Med
18336667Individual susceptibility to alcoholic pancreatitis. (2008 Mar)Apte MVJ Gastroenterol Hepatol
26521141Roflumilast partially reverses smoke-induced mucociliary dysfunction. (2015 Oct 31)Schmid ARespir Res
24568560Acquired defects in CFTR-dependent beta-adrenergic sweat secretion in chronic obstructive pulmonary disease. (2014 Feb 25)Courville CARespir Res
23226399MiR-101 and miR-144 regulate the expression of the CFTR chloride channel in the lung. (2012)Hassan FPLoS One
23431157Contribution of alpha7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure. (2013 Mar 5)Maouche KProc Natl Acad Sci U S A
19168702CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. (2009 Sep)Noe JAm J Respir Cell Mol Biol
24624459Pancreatitis Overview (1993)LaRusch J-
11194775Genetic risk factors for chronic obstructive pulmonary disease. (2000 Dec)Sandford AJClin Chest Med
20298391Genetic and biochemical markers of obstructive lung disease in the general population. (2009 Apr)Dahl MClin Respir J
22109105PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis. (2012 Feb)Gao FMol Med Rep
18230779Interactions between secondhand smoke and genes that affect cystic fibrosis lung disease. (2008 Jan 30)Collaco JMJAMA
26528246Mucociliary dysfunction in HIV and smoked substance abuse. (2015)Chinnapaiyan SFront Microbiol
24517344Impact of heterozygote CFTR mutations in COPD patients with chronic bronchitis. (2014 Feb 11)Raju SVRespir Res
25280757Intestinal current measurement versus nasal potential difference measurements for diagnosis of cystic fibrosis: a case-control study. (2014 Oct 4)Bagheri-Hanson ABMC Pulm Med
15528021Genetic counseling for hereditary pancreatitis--the role of molecular genetics testing for the cationic trypsinogen gene, cystic fibrosis and serine protease inhibitor Kazal type 1. (2004 Dec)Ellis IGastroenterol Clin North Am
29789655Cigarette smoke promotes HIV infection of primary bronchial epithelium and additively suppresses CFTR function. (2018 May 22)Chinnapaiyan SSci Rep
16163053Certain background factors exhibit an association with an increased risk for pancreatic calcification among Japanese male alcoholics. (2005 Oct)Nakamura YPancreas
26225835Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators. (2015 Nov)Clarke LAGenomics
26419886How does cigarette smoking cause acute pancreatitis? (2016 Mar-Apr)Barreto SGPancreatology
12403872Airways in cystic fibrosis are acidified: detection by exhaled breath condensate. (2002 Nov)Tate SThorax
22000714Nutritional status and eating disorders: neglected risks factor for nontuberculous mycobacterial lung disease? (2012 Jan)Portillo KMed Hypotheses
22608493[Chronic pancreatitis: beyond alcohol]. (2012 Oct)Vaquero Raya ECGastroenterol Hepatol