Gene: BVES

11149
HBVES|LGMD2X|POP1|POPDC1
blood vessel epicardial substance
protein-coding
6q21
Ensembl:ENSG00000112276 MIM:604577 Vega:OTTHUMG00000015291 UniprotKB:Q8NE79
NG_046732.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.888e-1 (AD)  6.185e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TMCC30.844
MYO1E0.842
CNKSR30.838
PRIMA10.836
FRMD4B0.83
PLD10.83
TMC60.824
PRR5L0.818
RASGRP30.812
NDE10.809

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CUX2-0.47
PRTN3-0.435
SHISA8-0.434
CDH22-0.428
POU3F1-0.427
SLC29A4-0.422
CHRNA2-0.422
KCNQ4-0.414
DBH-0.412
VIP-0.407

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
D020106AcrylamideAcrylamide results in decreased expression of BVES mRNA28959563
C006632arsenic trioxidearsenic trioxide results in increased expression of BVES mRNA27829220
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in decreased expression of BVES mRNA26377693
D001564Benzo(a)pyrene[Benzo(a)pyrene co-treated with fluoranthene] results in decreased expression of BVES mRNA25412620
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of BVES mRNA22228805|2373587
C006780bisphenol Abisphenol A results in increased expression of BVES mRNA26364221
C006780bisphenol Abisphenol A affects the methylation of BVES promoter27415467
C006780bisphenol Abisphenol A results in decreased expression of BVES mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of BVES mRNA26079696
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BVES mRNA20938992
C017180decamethrindecamethrin results in decreased expression of BVES mRNA19017407
D002945CisplatinCisplatin results in increased expression of BVES mRNA27392435
D004041Dietary FatsDietary Fats results in increased expression of BVES mRNA18042831
C118739entinostatentinostat results in increased expression of BVES mRNA27188386
C007738fluoranthene[Benzo(a)pyrene co-treated with fluoranthene] results in decreased expression of BVES mRNA25412620
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BVES mRNA20938992
C039281furanfuran results in increased methylation of BVES gene22079235
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of BVES mRNA22904298
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of BVES mRNA20938992
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in decreased expression of BVES mRNA22401849
D000073878Palm OilPalm Oil results in increased expression of BVES mRNA18042831
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in increased expression of BVES mRNA"25510870
D011441PropylthiouracilPropylthiouracil results in increased expression of BVES mRNA24780913
C009277sodium arsenatesodium arsenate results in increased expression of BVES mRNA21795629
D013096SpermineSpermine results in increased expression of BVES mRNA18673383
C009495titanium dioxidetitanium dioxide results in decreased expression of BVES mRNA23557971
D014212TretinoinTretinoin results in decreased expression of BVES mRNA20530235
D014212TretinoinTretinoin results in increased expression of BVES mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of BVES mRNA24935251|2718838
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BVES mRNA"26743178
D014520UrethaneUrethane results in increased expression of BVES mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of BVES mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of BVES mRNA23179753|2493525
C025643vinclozolinvinclozolin results in decreased expression of BVES mRNA21126777
C111237vorinostatvorinostat results in increased expression of BVES mRNA27188386

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005198structural molecule activity-IDA16188940  
GO:0005515protein binding-IPI26642364  
GO:0030552cAMP binding-IBA21873635  
GO:0030552cAMP binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001921positive regulation of receptor recycling-ISS-  
GO:0002027regulation of heart rate-IEA-  
GO:0002244hematopoietic progenitor cell differentiation-IEA-  
GO:0002931response to ischemia-ISS-  
GO:0007507heart development-IBA21873635  
GO:0007507heart development-IMP26642364  
GO:0007517muscle organ development-NAS10441744  
GO:0007519skeletal muscle tissue development-IBA21873635  
GO:0007519skeletal muscle tissue development-IMP26642364  
GO:0008360regulation of cell shape-ISS-  
GO:0016192vesicle-mediated transport-ISS-  
GO:0034446substrate adhesion-dependent cell spreading-ISS-  
GO:0040017positive regulation of locomotion-ISS-  
GO:0042391regulation of membrane potential-IBA21873635  
GO:0042391regulation of membrane potential-IEA-  
GO:0043087regulation of GTPase activity-ISS-  
GO:0048278vesicle docking-IEA-  
GO:0051146striated muscle cell differentiation-IBA21873635  
GO:0060931sinoatrial node cell development-IEA-  
GO:0060973cell migration involved in heart development-IEA-  
GO:0090136epithelial cell-cell adhesion-IDA16188940  
GO:2001135regulation of endocytic recycling-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IDA-  
GO:0005886plasma membrane-ISS-  
GO:0005901caveola-ISS-  
GO:0005923bicellular tight junction-IDA16188940  
GO:0016020membrane-IBA21873635  
GO:0016021integral component of membrane-IDA16188940  
GO:0016021integral component of membrane-NAS10441744  
GO:0016328lateral plasma membrane-IDA16188940  
GO:0030054cell junction-IDA-  
GO:0031253cell projection membrane-IEA-  
GO:0042383sarcolemma-IBA21873635  
GO:0042383sarcolemma-IDA26642364  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
18349282DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients. (2008 Mar)Feng QCancer Epidemiol Biomarkers Prev