| C490191 | 11,11'-dideoxyverticilin | "11,11'-dideoxyverticilin results in increased phosphorylation of CHEK2 protein" | 15963507 |
| C582286 | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein | 26208482 |
| C582286 | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein] | 26208482 |
| C582286 | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | "4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein]" | 26208482 |
| C582286 | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | CHEK2 mutant form results in increased susceptibility to 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | 26208482 |
| C582286 | 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea | MGMT mutant form promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein] | 26208482 |
| C051246 | 1-methylanthracene | [1-methylanthracene co-treated with fluoranthene] results in increased expression of CHEK2 mRNA | 28329830 |
| C532162 | 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine | "[OGT mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased phosphorylation of CHEK2 protein" | 23029544 |
| C546193 | 2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide | "2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein]" | 25977998 |
| C093973 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| C111118 | 2',3,3',4',5-pentachloro-4-hydroxybiphenyl | "2',3,3',4',5-pentachloro-4-hydroxybiphenyl results in decreased expression of CHEK2 mRNA" | 19114083 |
| C587734 | 2,3,5-trichloro-6-phenyl-(1,4)benzoquinone | "2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of CHEK2 protein" | 26451628 |
| C029497 | 2,3-bis(3'-hydroxybenzyl)butyrolactone | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHEK2 mRNA" | 19167446 |
| C416653 | 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone | 2-(3'-methoxyphenyl)-6-pyrrolidinyl-4-quinazolinone results in increased expression of and results in increased phosphorylation of CHEK2 protein | 23523585 |
| C023514 | 2,6-dinitrotoluene | "2,6-dinitrotoluene affects the expression of CHEK2 mRNA" | 21346803 |
| C031278 | 2-chloroethyl ethyl sulfide | 2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein | 19111594|2046991 |
| C031278 | 2-chloroethyl ethyl sulfide | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C031278 | 2-chloroethyl ethyl sulfide | ATM protein affects the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C031278 | 2-chloroethyl ethyl sulfide | ATR protein affects the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C031278 | 2-chloroethyl ethyl sulfide | wortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C031278 | 2-chloroethyl ethyl sulfide | 2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein | 20469912 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein] | 26208482 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK2 protein] | 22119920 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] | 25977998 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein]] | 24933654 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Sterigmatocystin results in increased expression of CHEK2 protein modified form] | 26914363 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein] | 20150440 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased expression of CHEK2 protein modified form | 26914363 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased phosphorylation of CHEK2 protein | 22119920 |
| C495818 | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [arsenic trioxide results in increased phosphorylation of CHEK2 protein] | 23337567 |
| C532363 | 3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide | 3-(carbamoylamino)-5-(3-fluorophenyl)-N-(3-piperidyl)thiophene-2-carboxamide results in decreased activity of CHEK2 protein | 23897988 |
| C009505 | 4,4'-diaminodiphenylmethane | "4,4'-diaminodiphenylmethane results in decreased expression of CHEK2 mRNA" | 18648102 |
| C086538 | 4-amino-1,8-naphthalimide | "4-amino-1,8-naphthalimide results in increased phosphorylation of CHEK2 protein" | 16556909 |
| C086538 | 4-amino-1,8-naphthalimide | "PARP1 protein affects the reaction [4-amino-1,8-naphthalimide results in increased phosphorylation of CHEK2 protein]" | 16556909 |
| C475622 | 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine | "4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine inhibits the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased phosphorylation of CHEK2 protein]" | 26208482 |
| C508085 | 4'-demethyldesoxypodophyllotoxin | 4'-demethyldesoxypodophyllotoxin analog binds to and results in decreased phosphorylation of CHEK2 protein | 25446499 |
| C556313 | 4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol | "4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol binds to and results in decreased activity of CHEK2 protein" | 21186793 |
| C556313 | 4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol | "4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]" | 21186793 |
| C080669 | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | "5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of CHEK2 protein modified form" | 23470866 |
| C080669 | 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one | "diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of CHEK2 protein modified form]" | 23470866 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of CHEK2 protein" | 23274516 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "Acetylcysteine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of CHEK2 protein]" | 23274516 |
| C516138 | (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine | "Caffeine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of CHEK2 protein]" | 23274516 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in decreased activity of CHEK2 protein | 23897988 |
| C054852 | 7-hydroxystaurosporine | [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA] | 22003191 |
| C054852 | 7-hydroxystaurosporine | [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Cisplatin results in increased expression of CHEK2 mRNA] | 22003191 |
| C054852 | 7-hydroxystaurosporine | 7-hydroxystaurosporine results in decreased activity of CHEK2 protein | 22003191 |
| C545735 | 7-nitro-1H-indole-2-carboxylic acid (4-(1-(guanidinohydrazone)ethyl)phenyl)amide | 7-nitro-1H-indole-2-carboxylic acid (4-(1-(guanidinohydrazone)ethyl)phenyl)amide results in decreased activity of CHEK2 protein | 21186793 |
| D000082 | Acetaminophen | Acetaminophen results in increased expression of CHEK2 mRNA | 22230336 |
| D000111 | Acetylcysteine | "Acetylcysteine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of CHEK2 protein]" | 23274516 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CHEK2 protein modified form] | 24792323 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]] | 15489221 |
| D000111 | Acetylcysteine | Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of CHEK2 protein] | 24933654 |
| D020106 | Acrylamide | Acrylamide results in increased expression of CHEK2 mRNA | 28959563 |
| C027955 | aflatoxin G1 | aflatoxin G1 results in increased activity of CHEK2 protein | 23907605 |
| C027955 | aflatoxin G1 | aflatoxin G1 results in increased expression of CHEK2 protein modified form | 23907605 |
| C027955 | aflatoxin G1 | Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of CHEK2 protein modified form] | 23907605 |
| C027955 | aflatoxin G1 | Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of CHEK2 protein modified form] | 23907605 |
| D013196 | Dihydrotestosterone | [Curcumin co-treated with Dihydrotestosterone] results in increased phosphorylation of CHEK2 protein | 21134073 |
| D013196 | Dihydrotestosterone | Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein] | 21134073 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of CHEK2 mRNA | 16483693 |
| D000643 | Ammonium Chloride | Ammonium Chloride results in increased expression of CHEK2 protein | 16483693 |
| D000872 | Anthocyanins | Anthocyanins results in increased phosphorylation of CHEK2 protein | 27444805 |
| D018501 | Antirheumatic Agents | Antirheumatic Agents results in decreased expression of CHEK2 mRNA | 24449571 |
| D016590 | Aphidicolin | Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] | 18158334 |
| D016590 | Aphidicolin | [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA] | 22003191 |
| D034341 | Aristolochic Acids | Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CHEK2 protein modified form] | 24792323 |
| D034341 | Aristolochic Acids | Aristolochic Acids results in increased expression of CHEK2 protein modified form | 24792323 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased expression of CHEK2 mRNA | 22521957 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein | 16891316|1848298 |
| C006632 | arsenic trioxide | PPM1D mutant form promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein] | 18482988 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased phosphorylation of and results in increased activity of CHEK2 protein | 16891316 |
| C006632 | arsenic trioxide | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [arsenic trioxide results in increased phosphorylation of CHEK2 protein] | 23337567 |
| C006632 | arsenic trioxide | arsenic trioxide results in increased phosphorylation of CHEK2 protein | 23337567 |
| C006632 | arsenic trioxide | arsenic trioxide inhibits the reaction [PPM1D protein results in decreased phosphorylation of CHEK2 protein] | 18482988 |
| D017636 | Asbestos, Amphibole | "Asbestos, Amphibole results in decreased expression of CHEK2 protein" | 20855422 |
| D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form] | 25977998 |
| D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] | 25977998 |
| D001205 | Ascorbic Acid | Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA] | 18544905 |
| D001241 | Aspirin | Aspirin results in increased expression of CHEK2 mRNA | 20457246 |
| D001280 | Atrazine | Atrazine results in increased expression of CHEK2 mRNA | 25929836 |
| D001280 | Atrazine | Atrazine results in increased expression of CHEK2 mRNA | 22515965 |
| C105832 | aurapten | aurapten affects the expression of CHEK2 mRNA | 23320178 |
| D001507 | Beclomethasone | Beclomethasone results in decreased expression of CHEK2 mRNA | 23656298 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of CHEK2 mRNA | 20064835|2180250 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of CHEK2 mRNA | 22641617 |
| D001599 | Berberine | Berberine results in increased expression of CHEK2 protein modified form | 23747414 |
| D004958 | Estradiol | Estradiol results in decreased expression of CHEK2 mRNA | 24349563 |
| D004958 | Estradiol | Estradiol results in decreased expression of CHEK2 mRNA | 23373633 |
| D004958 | Estradiol | ESR1 protein promotes the reaction [Estradiol results in increased expression of CHEK2 mRNA] | 25210133 |
| D004958 | Estradiol | Estradiol results in increased expression of CHEK2 mRNA | 25210133 |
| D004958 | Estradiol | Estradiol results in increased phosphorylation of CHEK2 protein | 23788033 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of CHEK2 protein] | 23788033 |
| C006780 | bisphenol A | bisphenol A affects the expression of CHEK2 mRNA | 21786754 |
| C006780 | bisphenol A | bisphenol A results in increased expression of CHEK2 mRNA | 29027980 |
| C006780 | bisphenol A | bisphenol A affects the expression of CHEK2 mRNA | 21786754 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of CHEK2 mRNA | 25181051 |
| C006780 | bisphenol A | bisphenol A results in increased phosphorylation of CHEK2 protein | 23788033|2534410 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of CHEK2 protein] | 23788033 |
| D001761 | Bleomycin | Bleomycin results in increased phosphorylation of CHEK2 protein | 24933654 |
| D001761 | Bleomycin | resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C000591165 | BO-1012 | BO-1012 results in decreased phosphorylation of CHEK2 protein | 24823293 |
| C557045 | BO-1051 | ATM protein promotes the reaction [BO-1051 results in increased expression of CHEK2 protein modified form] | 21184746 |
| C557045 | BO-1051 | BO-1051 results in increased expression of CHEK2 protein modified form | 21184746 |
| C471992 | bosutinib | bosutinib results in decreased activity of CHEK2 protein | 17114238 |
| C546611 | brevetoxin 2 | brevetoxin 2 results in increased expression of CHEK2 mRNA | 20498034 |
| D002066 | Busulfan | [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of CHEK2 protein | 20933509 |
| D019328 | Buthionine Sulfoximine | Buthionine Sulfoximine promotes the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form] | 25977998 |
| D002101 | Cacodylic Acid | Cacodylic Acid results in increased expression of CHEK2 mRNA | 17720352 |
| D019256 | Cadmium Chloride | Cadmium Chloride results in increased phosphorylation of CHEK2 protein | 20435356 |
| D002110 | Caffeine | "Caffeine inhibits the reaction [(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine results in increased phosphorylation of CHEK2 protein]" | 23274516 |
| D002110 | Caffeine | Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| D002110 | Caffeine | Caffeine inhibits the reaction [[resveratrol results in increased activity of [ATM protein co-treated with ATR protein]] results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]] | 15975956 |
| D002110 | Caffeine | Caffeine inhibits the reaction [resveratrol results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]] | 15975956 |
| D002110 | Caffeine | Caffeine inhibits the reaction [silybin results in increased phosphorylation of CHEK2 protein] | 16777994 |
| D002110 | Caffeine | Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] | 18158334 |
| D002110 | Caffeine | Caffeine results in decreased activity of CHEK2 protein | 10531013 |
| D002110 | Caffeine | Caffeine inhibits the reaction [ATM results in increased phosphorylation of and results in increased activity of CHEK2 protein] | 10744722 |
| C553149 | camphorquinone | camphorquinone results in increased phosphorylation of CHEK2 protein | 26658076 |
| D002166 | Camptothecin | Camptothecin results in increased expression of CHEK2 protein modified form | 25269479|2597799 |
| D002166 | Camptothecin | Camptothecin results in increased phosphorylation of CHEK2 protein | 21646468 |
| C081643 | candesartan | candesartan inhibits the reaction [AGT protein modified form results in increased phosphorylation of CHEK2 protein] | 18314486 |
| D002211 | Capsaicin | Capsaicin results in increased expression of CHEK2 mRNA | 19502594 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride results in increased expression of CHEK2 mRNA | 16644059 |
| D002794 | Choline | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHEK2 gene | 20938992 |
| C530333 | cis-diammine(pyridine)chloroplatinum(II) | cis-diammine(pyridine)chloroplatinum(II) results in increased phosphorylation of CHEK2 protein | 21750216 |
| C068329 | clofarabine | [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of CHEK2 protein | 20933509 |
| C068329 | clofarabine | [clofarabine co-treated with fludarabine] results in increased phosphorylation of CHEK2 protein | 20933509 |
| D003035 | Cobalt | Cobalt results in increased expression of CHEK2 mRNA | 22147119 |
| D003035 | Cobalt | [Organometallic Compounds co-treated with Cobalt] results in increased expression of CHEK2 mRNA | 22147119 |
| D003300 | Copper | [Thiosemicarbazones binds to Copper] which results in increased phosphorylation of CHEK2 protein | 20931265 |
| C464760 | copper-1,10-phenanthroline | "copper-1,10-phenanthroline results in increased phosphorylation of CHEK2 protein" | 24638265 |
| D019327 | Copper Sulfate | Copper Sulfate results in decreased expression of CHEK2 mRNA | 19549813 |
| D003375 | Coumestrol | "[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of CHEK2 mRNA" | 19167446 |
| D003375 | Coumestrol | [Coumestrol co-treated with resveratrol] results in increased expression of CHEK2 mRNA | 19167446 |
| C029892 | cupric chloride | cupric chloride results in increased phosphorylation of CHEK2 protein | 20435356 |
| D003471 | Cuprizone | Cuprizone results in increased expression of CHEK2 mRNA | 26577399 |
| D003474 | Curcumin | [Curcumin co-treated with Dihydrotestosterone] results in increased phosphorylation of CHEK2 protein | 21134073 |
| D003474 | Curcumin | [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein | 21134073 |
| D003474 | Curcumin | Curcumin results in increased phosphorylation of CHEK2 protein | 21134073 |
| D003474 | Curcumin | Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein] | 21134073 |
| D003474 | Curcumin | [Isoflavones co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein | 21134073 |
| C010902 | decabromobiphenyl ether | decabromobiphenyl ether affects the expression of CHEK2 mRNA | 24834073 |
| C114768 | decamethylcyclopentasiloxane | decamethylcyclopentasiloxane results in decreased expression of CHEK2 mRNA | 27601420 |
| C100261 | diacetyldiphenylurea bisguanylhydrazone | "diacetyldiphenylurea bisguanylhydrazone inhibits the reaction [5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one results in increased expression of CHEK2 protein modified form]" | 23470866 |
| C100261 | diacetyldiphenylurea bisguanylhydrazone | diacetyldiphenylurea bisguanylhydrazone results in decreased activity of CHEK2 protein | 23897988 |
| C100261 | diacetyldiphenylurea bisguanylhydrazone | diacetyldiphenylurea bisguanylhydrazone results in decreased activity of CHEK2 protein | 23470866 |
| D003993 | Dibutyl Phthalate | Dibutyl Phthalate results in decreased expression of CHEK2 mRNA | 21266533 |
| D002945 | Cisplatin | BMI1 inhibits the reaction [Cisplatin results in increased phosphorylation of CHEK2 protein] | 21445297 |
| D002945 | Cisplatin | Cisplatin results in increased activity of CHEK2 protein | 21324906|2159254 |
| D002945 | Cisplatin | Cisplatin results in increased expression of CHEK2 mRNA | 25450742 |
| D002945 | Cisplatin | Cisplatin results in increased phosphorylation of and results in increased activity of CHEK2 protein | 21107699 |
| D002945 | Cisplatin | Cisplatin results in increased phosphorylation of CHEK2 protein | 21285353|2144529 |
| D002945 | Cisplatin | ERCC6 protein inhibits the reaction [Cisplatin results in increased activity of CHEK2 protein] | 21324906 |
| D002945 | Cisplatin | MSH2 protein promotes the reaction [Cisplatin results in increased phosphorylation of CHEK2 protein] | 21285353 |
| D002945 | Cisplatin | [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Cisplatin results in increased expression of CHEK2 mRNA] | 22003191 |
| D002945 | Cisplatin | Cisplatin results in increased phosphorylation of CHEK2 protein | 21285353 |
| D002945 | Cisplatin | MSH2 protein promotes the reaction [Cisplatin results in increased phosphorylation of CHEK2 protein] | 21285353 |
| D002945 | Cisplatin | Cisplatin results in increased expression of CHEK2 protein modified form | 26739623 |
| D002945 | Cisplatin | Lovastatin inhibits the reaction [Cisplatin results in increased expression of CHEK2 protein modified form] | 26739623 |
| D004006 | Dichlorvos | Dichlorvos results in increased expression of CHEK2 mRNA | 24369695 |
| D004006 | Dichlorvos | Dichlorvos results in increased expression of CHEK2 protein | 24369695 |
| D004006 | Dichlorvos | TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA] | 24369695 |
| D004006 | Dichlorvos | TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein] | 24369695 |
| D004026 | Dieldrin | Dieldrin affects the expression of CHEK2 mRNA | 22546817 |
| D004052 | Diethylnitrosamine | Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA] | 18544905 |
| D004052 | Diethylnitrosamine | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA | 18253720 |
| D004052 | Diethylnitrosamine | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA | 22129741 |
| D004052 | Diethylnitrosamine | [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA | 18544905 |
| C011612 | diethyl sulfate | diethyl sulfate results in decreased expression of CHEK2 protein modified form | 23830811 |
| C011612 | diethyl sulfate | diethyl sulfate results in increased expression of CHEK2 protein modified form | 23830811 |
| C534866 | digalloylresveratrol | digalloylresveratrol results in increased activity of CHEK2 protein | 23943154 |
| D004074 | Digitoxin | Digitoxin analog results in decreased expression of CHEK2 protein | 22037315 |
| D004074 | Digitoxin | Digitoxin results in decreased expression of CHEK2 protein | 22037315 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of CHEK2 mRNA | 21592394 |
| D002117 | Calcitriol | [Testosterone co-treated with Calcitriol] results in decreased expression of CHEK2 mRNA | 21592394 |
| D004121 | Dimethyl Sulfoxide | Dimethyl Sulfoxide affects the expression of CHEK2 mRNA | 24834073 |
| D004237 | Diuron | Diuron results in increased expression of CHEK2 mRNA | 21551480 |
| D004317 | Doxorubicin | Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]] | 15489221 |
| D004317 | Doxorubicin | Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein] | 15489221 |
| D004317 | Doxorubicin | Doxorubicin results in increased phosphorylation of and results in increased activity of CHEK2 protein | 17320279|1834719 |
| D004317 | Doxorubicin | Doxorubicin results in increased phosphorylation of CHEK2 protein | 17085670|2164646 |
| D004317 | Doxorubicin | Go 6976 inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of CHEK2 protein] | 17320279 |
| D004317 | Doxorubicin | Doxorubicin results in increased phosphorylation of CHEK2 protein | 22242153 |
| D004317 | Doxorubicin | Doxorubicin results in decreased expression of CHEK2 mRNA | 19801496|2718193 |
| D004317 | Doxorubicin | Fungal Polysaccharides inhibits the reaction [Doxorubicin results in decreased expression of CHEK2 mRNA] | 27181935 |
| D004726 | Endosulfan | Endosulfan results in increased expression of CHEK2 mRNA | 22515965 |
| D005038 | Ethylnitrosourea | Ethylnitrosourea results in decreased expression of CHEK2 protein | 28549617 |
| D005047 | Etoposide | "4-fluoro-2-(4-(4-(2-hydroxypropan-2-yl)pyrrolidin-3-ylamino)-6,7-dimethoxyquinazolin-2-yl)phenol inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein]" | 21186793 |
| D005047 | Etoposide | Etoposide results in increased phosphorylation of CHEK2 protein | 21186793|2625960 |
| D005047 | Etoposide | pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein] | 26259609 |
| D005047 | Etoposide | Etoposide results in increased phosphorylation of CHEK2 protein | 22242153 |
| D011345 | Fenofibrate | [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CHEK2 mRNA | 18253720 |
| C017875 | fisetin | fisetin results in increased expression of CHEK2 protein | 28181380 |
| D044950 | Flavanones | Flavanones results in increased phosphorylation of CHEK2 protein | 21616090 |
| D005467 | Floxuridine | Floxuridine results in increased activity of CHEK2 protein | 22194930 |
| D005467 | Floxuridine | Floxuridine results in increased phosphorylation of and results in increased activity of CHEK2 protein | 21613406 |
| C024352 | fludarabine | [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased phosphorylation of CHEK2 protein | 20933509 |
| C024352 | fludarabine | [clofarabine co-treated with fludarabine] results in increased phosphorylation of CHEK2 protein | 20933509 |
| C007738 | fluoranthene | [1-methylanthracene co-treated with fluoranthene] results in increased expression of CHEK2 mRNA | 28329830 |
| C007738 | fluoranthene | fluoranthene results in increased expression of CHEK2 mRNA | 28329830 |
| D005472 | Fluorouracil | Fluorouracil results in increased phosphorylation of and results in increased activity of CHEK2 protein | 21613406 |
| D005485 | Flutamide | Flutamide inhibits the reaction [[Dihydrotestosterone co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein] | 21134073 |
| D005492 | Folic Acid | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHEK2 gene | 20938992 |
| D005557 | Formaldehyde | Formaldehyde results in decreased expression of CHEK2 mRNA | 23649840 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in increased phosphorylation of CHEK2 protein] | 23788033 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased phosphorylation of CHEK2 protein] | 23788033 |
| D062610 | Fungal Polysaccharides | Fungal Polysaccharides inhibits the reaction [Doxorubicin results in decreased expression of CHEK2 mRNA] | 27181935 |
| C039281 | furan | furan results in increased expression of CHEK2 mRNA | 20194422 |
| C039281 | furan | furan results in increased expression of CHEK2 mRNA | 25539665 |
| D005665 | Furosemide | Furosemide affects the expression of CHEK2 mRNA | 17497460 |
| D019833 | Genistein | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| D019833 | Genistein | Caffeine inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| D019833 | Genistein | Genistein results in increased phosphorylation of CHEK2 protein | 19038232 |
| D019833 | Genistein | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| C081021 | Go 6976 | Go 6976 inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of CHEK2 protein] | 17320279 |
| C001330 | hellebrigenin | hellebrigenin results in increased phosphorylation of CHEK2 protein | 24954031 |
| D006575 | Heterocyclic Compounds, 3-Ring | "Heterocyclic Compounds, 3-Ring results in increased phosphorylation of CHEK2 protein" | 21500194 |
| C024035 | hexamethylcyclotrisiloxane | hexamethylcyclotrisiloxane results in decreased expression of CHEK2 mRNA | 27601420 |
| D017313 | Fenretinide | Fenretinide results in increased expression of CHEK2 mRNA | 28973697 |
| D006861 | Hydrogen Peroxide | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein] | 24933654 |
| D006861 | Hydrogen Peroxide | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein]] | 24933654 |
| D006861 | Hydrogen Peroxide | Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein | 24933654|2620848 |
| D006861 | Hydrogen Peroxide | resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C016517 | indole-3-carbinol | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA | 22129741 |
| C051890 | irinotecan | irinotecan results in increased phosphorylation of CHEK2 protein | 22898888 |
| D007501 | Iron | [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CHEK2 mRNA | 22198552 |
| D007529 | Isoflavones | [Isoflavones co-treated with Curcumin] results in increased phosphorylation of CHEK2 protein | 21134073 |
| D007530 | Isoflurane | Isoflurane results in increased expression of CHEK2 mRNA | 16978161 |
| C410337 | K 7174 | K 7174 results in decreased expression of CHEK2 mRNA | 24086573 |
| C006552 | kaempferol | kaempferol results in increased phosphorylation of CHEK2 protein | 24595819 |
| C011890 | kojic acid | Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA] | 18544905 |
| C011890 | kojic acid | [kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA | 18544905 |
| D007854 | Lead | Lead affects the expression of CHEK2 mRNA | 22313790 |
| C038753 | leptomycin B | [leptomycin B co-treated with TP53 gene mutant form] results in decreased expression of CHEK2 mRNA | 20803015 |
| C506643 | liposomal doxorubicin | liposomal doxorubicin results in increased phosphorylation of CHEK2 protein | 27923599 |
| D008148 | Lovastatin | Lovastatin inhibits the reaction [Cisplatin results in increased expression of CHEK2 protein modified form] | 26739623 |
| C005095 | malachite green | malachite green results in decreased phosphorylation of CHEK2 protein | 16085357 |
| D008558 | Melphalan | Melphalan results in increased phosphorylation of CHEK2 protein | 26208482 |
| D008715 | Methionine | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CHEK2 gene | 20938992 |
| D008730 | Methoxsalen | Methoxsalen inhibits the reaction [aflatoxin G1 results in increased expression of CHEK2 protein modified form] | 23907605 |
| C005223 | methyleugenol | methyleugenol results in decreased expression of CHEK2 mRNA | 26011634 |
| C008461 | methyl isocyanate | methyl isocyanate results in decreased expression of CHEK2 mRNA | 22223508 |
| C004925 | methylmercuric chloride | methylmercuric chloride affects the expression of CHEK2 mRNA | 20864626 |
| D008770 | Methylnitrosourea | Methylnitrosourea results in increased phosphorylation of CHEK2 protein | 21285353 |
| D008770 | Methylnitrosourea | MSH2 protein promotes the reaction [Methylnitrosourea results in increased phosphorylation of CHEK2 protein] | 21285353 |
| C008493 | methylselenic acid | methylselenic acid results in increased expression of CHEK2 mRNA | 12517777 |
| D015741 | Metribolone | [Curcumin co-treated with Metribolone] results in increased phosphorylation of CHEK2 protein | 21134073 |
| D015741 | Metribolone | Metribolone results in increased phosphorylation of CHEK2 protein | 23272087 |
| D016685 | Mitomycin | Mitomycin results in increased phosphorylation of CHEK2 protein | 26208482 |
| D016686 | Monocrotaline | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA | 21224054 |
| C008548 | morin | morin results in decreased expression of CHEK2 mRNA | 28689916 |
| D009151 | Mustard Gas | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK2 protein] | 22119920 |
| D009151 | Mustard Gas | Mustard Gas results in increased phosphorylation of CHEK2 protein | 22119920 |
| D009151 | Mustard Gas | wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK2 protein] | 22119920 |
| D009151 | Mustard Gas | Mustard Gas results in increased expression of CHEK2 mRNA | 18955075 |
| C005246 | myristicin | myristicin results in decreased expression of CHEK2 mRNA | 24792648 |
| C017096 | n-butoxyethanol | n-butoxyethanol results in increased expression of CHEK2 mRNA | 19812364 |
| D009532 | Nickel | [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CHEK2 mRNA | 22198552 |
| D009538 | Nicotine | Nicotine inhibits the reaction [aflatoxin G1 results in increased expression of CHEK2 protein modified form] | 23907605 |
| C047330 | N-methylisoindigotin | N-methylisoindigotin results in increased phosphorylation of CHEK2 protein | 26887594 |
| C010615 | Nonidet P-40 | Nonidet P-40 results in increased expression of CHEK2 mRNA | 26552463 |
| C069741 | norcantharidin | norcantharidin results in increased phosphorylation of CHEK2 protein | 21266192 |
| D016912 | Levonorgestrel | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CHEK2 mRNA | 19074003 |
| C553898 | NSC 724998 | NSC 724998 results in increased expression of CHEK2 protein modified form | 25269479 |
| C024064 | octamethylcyclotetrasiloxane | octamethylcyclotetrasiloxane results in decreased expression of CHEK2 mRNA | 27601420 |
| C507134 | ON 01910 | ON 01910 results in increased phosphorylation of CHEK2 protein | 21646468 |
| D009942 | Organometallic Compounds | [Organometallic Compounds co-treated with Cobalt] results in increased expression of CHEK2 mRNA | 22147119 |
| C030110 | oxaliplatin | oxaliplatin results in increased phosphorylation of CHEK2 protein | 21750216 |
| C030110 | oxaliplatin | [oxaliplatin co-treated with Topotecan] results in decreased expression of CHEK2 mRNA | 25729387 |
| D052638 | Particulate Matter | Particulate Matter results in increased expression of CHEK2 mRNA | 24769257 |
| D010416 | Pentachlorophenol | Pentachlorophenol results in increased expression of CHEK2 mRNA | 24642059 |
| D010424 | Pentobarbital | Pentobarbital results in increased expression of CHEK2 mRNA | 16978161 |
| D010672 | Phenytoin | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA | 21224054 |
| C121565 | pifithrin | pifithrin inhibits the reaction [Etoposide results in increased phosphorylation of CHEK2 protein] | 26259609 |
| D010936 | Plant Extracts | Plant Extracts results in increased phosphorylation of CHEK2 protein | 24595819 |
| D010984 | Platinum | Platinum analog results in increased phosphorylation of and results in increased activity of CHEK2 protein | 21107699 |
| C060540 | polyhexamethyleneguanidine | polyhexamethyleneguanidine results in decreased expression of CHEK2 mRNA | 24583197 |
| C027373 | potassium chromate(VI) | "2-(2,6-dimethylmorpholin-4-yl)-N-(5-(6-morpholin-4-yl-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein]" | 25977998 |
| C027373 | potassium chromate(VI) | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] | 25977998 |
| C027373 | potassium chromate(VI) | Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form] | 25977998 |
| C027373 | potassium chromate(VI) | Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] | 25977998 |
| C027373 | potassium chromate(VI) | ATM protein promotes the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein] | 25977998 |
| C027373 | potassium chromate(VI) | Buthionine Sulfoximine promotes the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form] | 25977998 |
| C027373 | potassium chromate(VI) | CHEK2 protein promotes the reaction [potassium chromate(VI) results in increased expression of TRIM28 protein modified form] | 25977998 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in increased expression of CHEK2 protein modified form | 25977998 |
| C027373 | potassium chromate(VI) | potassium chromate(VI) results in increased phosphorylation of CHEK2 protein | 25977998 |
| D011398 | Promethazine | Promethazine results in decreased expression of CHEK2 mRNA | 26011634 |
| D011441 | Propylthiouracil | Propylthiouracil results in increased expression of CHEK2 mRNA | 24780913 |
| C010423 | pyrithione zinc | pyrithione zinc results in increased expression of CHEK2 mRNA | 21424779 |
| D011794 | Quercetin | Quercetin results in increased phosphorylation of and results in increased activity of CHEK2 protein | 19009557 |
| D011794 | Quercetin | Quercetin results in increased phosphorylation of CHEK2 protein | 24595819 |
| C059514 | resveratrol | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein]] | 24933654 |
| C059514 | resveratrol | Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C059514 | resveratrol | Caffeine inhibits the reaction [[resveratrol results in increased activity of [ATM protein co-treated with ATR protein]] results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]] | 15975956 |
| C059514 | resveratrol | Caffeine inhibits the reaction [resveratrol results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]] | 15975956 |
| C059514 | resveratrol | [Coumestrol co-treated with resveratrol] results in increased expression of CHEK2 mRNA | 19167446 |
| C059514 | resveratrol | resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C059514 | resveratrol | resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of CHEK2 protein] | 24933654 |
| C059514 | resveratrol | [resveratrol results in increased activity of [ATM protein co-treated with ATR protein]] results in increased activity of [CHEK1 protein co-treated with CHEK2 protein] | 15975956 |
| C059514 | resveratrol | resveratrol results in increased activity of [CHEK1 protein co-treated with CHEK2 protein] | 15975956 |
| C059514 | resveratrol | [resveratrol results in increased activity of [CHEK1 protein co-treated with CHEK2 protein]] which results in increased phosphorylation of CDC25C protein | 15975956 |
| C059514 | resveratrol | resveratrol results in increased phosphorylation of CHEK2 protein | 20080969|2315279 |
| C059514 | resveratrol | [temozolomide co-treated with resveratrol] results in increased phosphorylation of CHEK2 protein | 23522185 |
| C547185 | riccardin D | riccardin D affects the phosphorylation of CHEK2 protein | 24069304 |
| D012293 | Rifampin | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA | 21224054 |
| C009250 | sevoflurane | sevoflurane results in increased expression of CHEK2 mRNA | 26206149 |
| D012822 | Silicon Dioxide | Silicon Dioxide analog results in decreased expression of CHEK2 mRNA | 25895662 |
| D012835 | Silver Nitrate | Silver Nitrate analog results in increased expression of CHEK2 mRNA | 22831968 |
| C440975 | silybin | Caffeine inhibits the reaction [silybin results in increased phosphorylation of CHEK2 protein] | 16777994 |
| C440975 | silybin | silybin results in increased phosphorylation of CHEK2 protein | 16777994 |
| C017947 | sodium arsenite | CHEK2 protein affects the reaction [sodium arsenite results in increased expression of RIPK2 mRNA modified form] | 24865968 |
| C017947 | sodium arsenite | sodium arsenite promotes the reaction [CHEK2 protein results in increased phosphorylation of ELAVL1 protein] | 24865968 |
| C017947 | sodium arsenite | [sodium arsenite promotes the reaction [CHEK2 protein results in increased phosphorylation of ELAVL1 protein]] promotes the reaction [[ELAVL1 protein binds to TRA2B exon] which results in increased expression of TRA2B mRNA modified form] | 24865968 |
| C017947 | sodium arsenite | sodium arsenite results in increased phosphorylation of CHEK2 protein | 24865968 |
| C017947 | sodium arsenite | sodium arsenite results in increased expression of CHEK2 protein modified form | 24866292 |
| C017947 | sodium arsenite | CHEK2 protein affects the reaction [sodium arsenite results in decreased expression of HSP90AB1 mRNA] | 18996350 |
| C017947 | sodium arsenite | CHEK2 protein affects the reaction [sodium arsenite results in increased phosphorylation of TRP53 protein] | 18996350 |
| C017947 | sodium arsenite | sodium arsenite results in increased phosphorylation of CHEK2 protein | 18996350 |
| D053260 | Soot | Soot results in increased expression of CHEK2 mRNA | 26551751 |
| D053260 | Soot | Soot results in decreased expression of CHEK2 mRNA | 21914721 |
| D013241 | Sterigmatocystin | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Sterigmatocystin results in increased expression of CHEK2 protein modified form] | 26914363 |
| D013241 | Sterigmatocystin | Sterigmatocystin results in increased expression of CHEK2 protein modified form | 26914363 |
| D013605 | T-2 Toxin | 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [T-2 Toxin results in increased activity of CHEK2 protein] | 20150440 |
| D013605 | T-2 Toxin | T-2 Toxin results in increased activity of CHEK2 protein | 20150440 |
| C047246 | temozolomide | AKT1 protein inhibits the reaction [temozolomide results in increased phosphorylation of CHEK2 protein] | 15930307 |
| C047246 | temozolomide | [temozolomide co-treated with resveratrol] results in increased phosphorylation of CHEK2 protein | 23522185 |
| C047246 | temozolomide | temozolomide results in increased phosphorylation of CHEK2 protein | 15930307|2352218 |
| C505333 | TEMPOL-H | TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA] | 24369695 |
| C505333 | TEMPOL-H | TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein] | 24369695 |
| D013739 | Testosterone | [Testosterone co-treated with Calcitriol] results in decreased expression of CHEK2 mRNA | 21592394 |
| D013739 | Testosterone | Testosterone results in decreased expression of CHEK2 mRNA | 21592394 |
| C010792 | testosterone undecanoate | [testosterone undecanoate co-treated with Levonorgestrel] results in decreased expression of CHEK2 mRNA | 19074003 |
| C010792 | testosterone undecanoate | testosterone undecanoate results in decreased expression of CHEK2 mRNA | 19074003 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin affects the expression of CHEK2 mRNA | 21570461 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of CHEK2 mRNA | 15310856|1566782 |
| D013853 | Thioacetamide | Thioacetamide results in decreased expression of CHEK2 mRNA | 26011634 |
| D013882 | Thiosemicarbazones | [Thiosemicarbazones binds to Copper] which results in increased phosphorylation of CHEK2 protein | 20931265 |
| D019772 | Topotecan | [oxaliplatin co-treated with Topotecan] results in decreased expression of CHEK2 mRNA | 25729387 |
| D019772 | Topotecan | Topotecan results in decreased expression of CHEK2 mRNA | 25729387 |
| D019772 | Topotecan | Topotecan results in increased activity of CHEK2 protein | 22101337 |
| D014118 | Toxins, Biological | "Toxins, Biological affects the expression of CHEK2 mRNA" | 19682533 |
| C012589 | trichostatin A | trichostatin A results in increased expression of CHEK2 mRNA | 15901671 |
| C012589 | trichostatin A | trichostatin A results in decreased expression of CHEK2 mRNA | 23770000 |
| C015559 | trimellitic anhydride | trimellitic anhydride results in increased expression of CHEK2 mRNA | 19042947 |
| C005445 | triphenyl phosphate | triphenyl phosphate results in decreased expression of CHEK2 mRNA | 26898711 |
| D014414 | Tungsten | [Nickel co-treated with Iron co-treated with Tungsten] results in decreased expression of CHEK2 mRNA | 22198552 |
| C113580 | U 0126 | U 0126 inhibits the reaction [Genistein results in increased phosphorylation of CHEK2 protein] | 19038232 |
| D014520 | Urethane | Urethane results in increased expression of CHEK2 mRNA | 28818685 |
| C073339 | usnic acid | usnic acid results in increased expression of CHEK2 protein modified form | 27369375 |
| D014635 | Valproic Acid | Valproic Acid results in increased expression of CHEK2 mRNA | 15901671 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of CHEK2 gene | 29154799 |
| D001335 | Vehicle Emissions | Vehicle Emissions analog results in increased phosphorylation of CHEK2 protein | 25500124 |
| D001335 | Vehicle Emissions | Vehicle Emissions analog results in increased phosphorylation of CHEK2 protein | 25500124 |
| D014750 | Vincristine | Vincristine results in decreased expression of CHEK2 mRNA | 23649840 |
| C520468 | VRX0466617 | VRX0466617 results in decreased activity of CHEK2 protein | 21186793 |
| C009687 | wortmannin | wortmannin inhibits the reaction [2-chloroethyl ethyl sulfide results in increased phosphorylation of CHEK2 protein] | 19111594 |
| C009687 | wortmannin | wortmannin inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK2 protein] | 22119920 |
| C009687 | wortmannin | wortmannin results in decreased phosphorylation of CHEK2 protein | 22119920 |
| D015215 | Zidovudine | Zidovudine results in decreased expression of CHEK2 protein | 19541796 |
| D015215 | Zidovudine | Zidovudine results in increased phosphorylation of CHEK2 protein | 19541796 |