Gene: RNF24

11237
G1L
ring finger protein 24
protein-coding
20p13
Ensembl:ENSG00000101236 MIM:612489 Vega:OTTHUMG00000031770 UniprotKB:Q9Y225
NC_000020.11
PubMed
0   ANCO-SNPs
ND
1   
1.545e-1 (AD)  4.517e-1 (ND)   (Frontal_Cortex)
5.640e-1 (AD)  2.921e-1 (ND)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg23834525chr20:3995385RNF24Promoter1.321e-4Alcohol use disorders26763658

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CELF10.9
IP6K10.895
TMEM1270.892
CLASP10.891
YY10.89
SIRPA0.888
SIPA1L10.887
TM9SF40.884
SMG70.883
RERE0.881

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.683
OR4F29-0.635
SH2D1A-0.35
ANXA13-0.333
SNHG18-0.327
CTNNA3-0.31
CD8B-0.307
KLRC2-0.305
C5orf64-0.301
TFPI2-0.293

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0284741,4-bis(2-(3,5-dichloropyridyloxy))benzene"1,4-bis(2-(3,5-dichloropyridyloxy))benzene results in increased expression of RNF24 mRNA"28903501
D000082AcetaminophenAcetaminophen results in increased expression of RNF24 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of RNF24 mRNA17562736
C006418adrenocorticotropin zincadrenocorticotropin zinc results in decreased expression of RNF24 mRNA19920212
C006632arsenic trioxidearsenic trioxide results in increased expression of RNF24 mRNA15761015
C044887beta-methylcholinebeta-methylcholine affects the expression of RNF24 mRNA21179406
C006780bisphenol Abisphenol A results in increased expression of RNF24 mRNA29275510
C006780bisphenol Abisphenol A results in decreased expression of RNF24 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RNF24 mRNA28628672
D002994ClofibrateClofibrate results in increased expression of RNF24 mRNA23811191
C018021cobaltous chloridecobaltous chloride results in decreased expression of RNF24 mRNA24612858
D016572CyclosporineCyclosporine results in increased expression of RNF24 mRNA20106945
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RNF24 mRNA28628672
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of RNF24 mRNA28962523
D002945CisplatinCisplatin results in decreased expression of RNF24 mRNA27594783
D004041Dietary FatsDietary Fats affects the expression of RNF24 mRNA19680557
D004147DioxinsDioxins affects the expression of RNF24 mRNA20463971
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of RNF24 mRNA28196854
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in increased expression of RNF24 mRNA23649840
D005557FormaldehydeFormaldehyde results in increased expression of RNF24 mRNA23649840|2766457
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of RNF24 mRNA22634610
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RNF24 mRNA28628672
D007213IndomethacinIndomethacin results in decreased expression of RNF24 mRNA28201806
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of RNF24 mRNA28628672
C410337K 7174K 7174 results in increased expression of RNF24 mRNA24086573
D058185Magnetite Nanoparticles[Polyethyleneimine co-treated with Magnetite Nanoparticles] results in decreased expression of RNF24 mRNA26378955
D058185Magnetite Nanoparticles[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RNF24 mRNA26378955
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of RNF24 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of RNF24 mRNA23649840
C029938nickel sulfatenickel sulfate results in decreased expression of RNF24 mRNA22714537
C005290oxybenzoneoxybenzone results in increased expression of RNF24 mRNA22721600
D000073878Palm OilPalm Oil affects the expression of RNF24 mRNA19680557
C006253pirinixic acidpirinixic acid results in increased expression of RNF24 mRNA23811191
D011094Polyethyleneimine[Polyethyleneimine co-treated with Magnetite Nanoparticles] results in decreased expression of RNF24 mRNA26378955
D011794QuercetinQuercetin results in increased expression of RNF24 mRNA21632981
D012906SmokeSmoke results in increased expression of RNF24 mRNA21095227
D004113Succimer[Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of RNF24 mRNA26378955
D000952Antigens, Polyomavirus Transforming"Antigens, Polyomavirus Transforming results in decreased expression of RNF24 mRNA"26680231
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of RNF24 mRNA21570461|2637764
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in decreased expression of RNF24 mRNA25975270
D014241TrichloroethyleneTrichloroethylene results in increased expression of RNF24 mRNA25549359
D014415TunicamycinTunicamycin results in decreased expression of RNF24 mRNA22378314
D014520UrethaneUrethane results in increased expression of RNF24 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of RNF24 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of RNF24 mRNA27188386
D014635Valproic AcidValproic Acid results in increased expression of RNF24 mRNA24935251

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI25416956  
GO:0008270zinc ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0000139Golgi membrane-IEA-  
GO:0005794Golgi apparatus-IDA-  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
19147396Gene expression in human oral squamous cell carcinoma is influenced by risk factor exposure. (2009 Aug)Cheong SCOral Oncol