Gene: C1QTNF5

114902
CTRP5
C1q and TNF related 5
protein-coding
11q23.3
Ensembl:ENSG00000223953 MIM:608752 Vega:OTTHUMG00000166198 UniprotKB:Q9BXJ0
NG_012235.1
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LCAT0.78
RARRES20.764
TAX1BP30.759
RENBP0.755
HSD17B140.754
HMG20B0.753
FLT3LG0.753
DDAH20.752
CTSH0.749
MVB12A0.745

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GPR52-0.531
STYK1-0.522
HTR3B-0.516
C1QL3-0.514
SCN8A-0.507
ANO3-0.506
ZDHHC23-0.505
MCHR2-0.501
GRIN2B-0.499
CDH12-0.495

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of C1QTNF5 mRNA"26377693
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of C1QTNF5 mRNA"23146750
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of C1QTNF5 mRNA]"19414516
C4049102,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of C1QTNF5 mRNA]"19414516
C0140242,4,5,2',4',5'-hexachlorobiphenyl"2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of C1QTNF5 mRNA"23146750
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QTNF5 mRNA"28973690
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of C1QTNF5 mRNA"23146750
D000082AcetaminophenAcetaminophen affects the expression of C1QTNF5 mRNA17562736
D000242Cyclic AMP"2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of C1QTNF5 mRNA]"19414516
D001507BeclomethasoneBeclomethasone results in increased expression of C1QTNF5 mRNA23656298
C006703benzo(b)fluoranthenebenzo(b)fluoranthene results in increased expression of C1QTNF5 mRNA26377693
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of C1QTNF5 mRNA22316170
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [AHR protein binds to C1QTNF5 promoter]19654925
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of C1QTNF5 mRNA22610609|2719552
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of C1QTNF5 mRNA"20382639
C006780bisphenol Abisphenol A results in decreased expression of C1QTNF5 mRNA23146750
C006780bisphenol Abisphenol A affects the expression of C1QTNF5 mRNA21786754
C006780bisphenol Abisphenol A affects the expression of C1QTNF5 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of C1QTNF5 mRNA28628672
D002922CiguatoxinsCiguatoxins affects the expression of C1QTNF5 mRNA18353800
C018021cobaltous chloridecobaltous chloride results in decreased expression of C1QTNF5 mRNA19320972
D003471CuprizoneCuprizone results in decreased expression of C1QTNF5 mRNA27523638
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of C1QTNF5 mRNA28628672
D003907DexamethasoneDexamethasone results in increased expression of C1QTNF5 mRNA22733784
C016366dibenzothiophenedibenzothiophene results in decreased expression of C1QTNF5 mRNA23656968
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of C1QTNF5 mRNA21266533
C039281furanfuran results in increased expression of C1QTNF5 mRNA27387713
D017313FenretinideFenretinide results in increased expression of C1QTNF5 mRNA28973697
D006830Hydralazine[Hydralazine co-treated with Valproic Acid] results in increased expression of C1QTNF5 mRNA17183730
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of C1QTNF5 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of C1QTNF5 mRNA28628672
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of C1QTNF5 mRNA26644586
D048628KetolidesKetolides analog results in decreased expression of C1QTNF5 mRNA24967691
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of C1QTNF5 mRNA23458150
D008777MethyltestosteroneMethyltestosterone results in decreased expression of C1QTNF5 mRNA29191790
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in increased expression of C1QTNF5 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in increased expression of C1QTNF5 mRNA"25554681
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of C1QTNF5 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of C1QTNF5 mRNA25729387
D010416PentachlorophenolPentachlorophenol results in increased expression of C1QTNF5 mRNA23892564
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of C1QTNF5 mRNA23146750
D010936Plant ExtractsPlant Extracts results in decreased expression of C1QTNF5 mRNA23557933
C005556propionaldehydepropionaldehyde results in decreased expression of C1QTNF5 mRNA26079696
D011441PropylthiouracilPropylthiouracil results in decreased expression of C1QTNF5 mRNA24780913
C513428pyrachlostrobinpyrachlostrobin results in increased expression of C1QTNF5 mRNA27029645
C030984pyrenepyrene results in decreased expression of C1QTNF5 mRNA23656968
D012715Sesame OilSesame Oil results in increased expression of C1QTNF5 mRNA29191790
D012999SomanSoman results in increased expression of C1QTNF5 mRNA19281266
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of C1QTNF5 mRNA16443690|1849575
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of C1QTNF5 mRNA25729387
D019772TopotecanTopotecan results in increased expression of C1QTNF5 mRNA25729387
D014212TretinoinTretinoin results in increased expression of C1QTNF5 mRNA18230668
D014635Valproic Acid[Hydralazine co-treated with Valproic Acid] results in increased expression of C1QTNF5 mRNA17183730

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0042802identical protein binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0009306protein secretion-IEA-  
GO:0048839inner ear development-IEA-  
GO:0070206protein trimerization-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005581collagen trimer-IEA-  
GO:0005615extracellular space-IBA21873635  
GO:0005615extracellular space-IEA-  
GO:0005886plasma membrane-IBA21873635  
GO:0005923bicellular tight junction-IEA-  
GO:0016324apical plasma membrane-IEA-  
GO:0016328lateral plasma membrane-IEA-  
GO:0030133transport vesicle-IEA-  
GO:0042995cell projection-IBA21873635  
GO:0042995cell projection-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
17766366Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people. (2008 Jan)Yamada YJ Med Genet