Gene: C1QTNF7

114905
CTRP7|ZACRP7
C1q and TNF related 7
protein-coding
4p15.32
Ensembl:ENSG00000163145 Vega:OTTHUMG00000097095 UniprotKB:Q9BXJ2
NC_000004.12
PubMed
AD
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.054e-1 (AD)  6.201e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR51E10.826
ALX40.815
CDC20B0.809
SLC5A50.791
GATA60.785
SLC22A80.776
TRABD2B0.773
KLHL300.773
NR2F2-AS10.748
MYOCD0.747

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FEZF2-0.286
PNPLA7-0.276
UCN-0.274
PLK5-0.27
MYBPHL-0.267
KIAA0930-0.266
RHCG-0.265
DUSP9-0.257
UBAP1L-0.255
MOXD1-0.246

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in increased expression of C1QTNF7 mRNA"26377693
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in decreased expression of C1QTNF7 mRNA"20816883
D000082AcetaminophenAcetaminophen affects the expression of C1QTNF7 mRNA17562736
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of C1QTNF7 gene27153756
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of C1QTNF7 mRNA21298039
D001151ArsenicArsenic affects the methylation of C1QTNF7 gene25304211
C006632arsenic trioxidearsenic trioxide results in decreased expression of C1QTNF7 mRNA26705709
C547126AZM551248AZM551248 results in decreased expression of C1QTNF7 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of C1QTNF7 mRNA27195522
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of C1QTNF7 mRNA20660070
C006780bisphenol Abisphenol A results in decreased expression of C1QTNF7 mRNA25181051
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF7 mRNA20938992
D016572CyclosporineCyclosporine results in decreased methylation of C1QTNF7 promoter27989131
C010902decabromobiphenyl etherdecabromobiphenyl ether results in decreased expression of C1QTNF7 mRNA23640034
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of C1QTNF7 mRNA21266533
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF7 mRNA20938992
C039281furanfuran results in increased expression of C1QTNF7 mRNA27387713
D017313FenretinideFenretinide results in decreased expression of C1QTNF7 mRNA28973697
D008694Methamphetamine[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA19564919
D008694MethamphetamineMethamphetamine results in decreased expression of C1QTNF7 mRNA19564919
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of C1QTNF7 mRNA20938992
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of C1QTNF7 mRNA"25554681|2562005
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of C1QTNF7 mRNA"25554681
D009532NickelNickel results in decreased expression of C1QTNF7 mRNA25583101
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA27935865
C572573N-nitroso-tris-chloroethylurea[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF7 mRNA27935865
C060836pioglitazone[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA27935865
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of C1QTNF7 mRNA20660070
C534628SCH 23390[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA19564919
C534628SCH 23390SCH 23390 results in decreased expression of C1QTNF7 mRNA19564919
D053260SootSoot results in decreased expression of C1QTNF7 mRNA26551751
D014635Valproic AcidValproic Acid results in decreased expression of C1QTNF7 mRNA23179753
C581157XL147[N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of C1QTNF7 mRNA27935865

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0005581collagen trimer-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
20585324Genome-wide association study of conduct disorder symptomatology. (2011 Aug)Dick DMMol Psychiatry