| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| IL2RB | 0.896 |
| KLRF1 | 0.877 |
| TBX21 | 0.863 |
| DPPA4 | 0.854 |
| MROH5 | 0.85 |
| GADL1 | 0.845 |
| GZMA | 0.838 |
| CD3G | 0.836 |
| LY9 | 0.831 |
| KIR2DS4 | 0.823 |
| Gene Symbol | Pearson Correlation Coefficient |
|---|---|
| CHST1 | -0.457 |
| ADCY2 | -0.457 |
| CYP46A1 | -0.456 |
| LGI1 | -0.455 |
| TMEM56 | -0.454 |
| GDF10 | -0.454 |
| CDS1 | -0.452 |
| FUT9 | -0.45 |
| C1orf53 | -0.443 |
| C11orf49 | -0.439 |
| ID | Drug Name | Action | PubMed |
|---|---|---|---|
| C009505 | 4,4'-diaminodiphenylmethane | "4,4'-diaminodiphenylmethane results in increased expression of FCRL3 mRNA" | 18648102 |
| D000638 | Amiodarone | Amiodarone results in increased expression of FCRL3 mRNA | 19774075 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of FCRL3 mRNA | 22316170 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of FCRL3 mRNA | 25181051 |
| D003471 | Cuprizone | Cuprizone results in decreased expression of FCRL3 mRNA | 27523638 |
| D015759 | Ionomycin | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FCRL3 mRNA | 25613284 |
| D009532 | Nickel | Nickel results in increased expression of FCRL3 mRNA | 24768652|2558310 |
| D013755 | Tetradecanoylphorbol Acetate | [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FCRL3 mRNA | 25613284 |
| D014635 | Valproic Acid | Valproic Acid results in decreased methylation of FCRL3 gene | 29154799 |
| D001335 | Vehicle Emissions | Vehicle Emissions results in decreased methylation of FCRL3 gene | 25487561 |
| C088658 | zoledronic acid | zoledronic acid results in increased expression of FCRL3 mRNA | 24714768 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0019900 | kinase binding | - | IPI | 19843936 |
| GO:0019902 | phosphatase binding | - | IPI | 19843936 |
| GO:0019903 | protein phosphatase binding | - | IPI | 12051764 |
| GO:1990782 | protein tyrosine kinase binding | - | IPI | 12051764 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0002638 | negative regulation of immunoglobulin production | - | IDA | 23857366 |
| GO:0030890 | positive regulation of B cell proliferation | - | IDA | 23857366 |
| GO:0034163 | regulation of toll-like receptor 9 signaling pathway | - | IDA | 23857366 |
| GO:0043410 | positive regulation of MAPK cascade | - | IDA | 23857366 |
| GO:0045577 | regulation of B cell differentiation | - | IDA | 23857366 |
| GO:0050859 | negative regulation of B cell receptor signaling pathway | - | IDA | 19843936 |
| GO:0050864 | regulation of B cell activation | - | IDA | 23857366 |
| GO:0090279 | regulation of calcium ion import | - | IDA | 19843936 |
| GO:1905184 | positive regulation of protein serine/threonine phosphatase activity | - | IDA | 12051764 |
| GO ID | GO Term | Qualifier | Evidence | PubMed |
|---|---|---|---|---|
| GO:0005886 | plasma membrane | - | IEA | - |
| GO:0009986 | cell surface | - | IDA | 16849395 |
| GO:0016021 | integral component of membrane | - | IEA | - |
| KEGG ID | KEGG Term |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|
| PMID | Title (Year) | Author | Journal |
|---|---|---|---|
| 20234359 | Ethnogenetic heterogeneity of rheumatoid arthritis-implications for pathogenesis. (2010 May) | Kochi Y | Nat Rev Rheumatol |
| 20453439 | Genetic background of tolerance breakdown in rheumatoid arthritis. (2010) | Kochi Y | Nihon Rinsho Meneki Gakkai Kaishi |
| 25421156 | Role of genetic and non-genetic factors in the etiology of Graves' disease. (2015 Mar) | Marino M | J Endocrinol Invest |
| 25231450 | Thyroid autoimmunity. (2014) | Wiersinga WM | Endocr Dev |