Gene: ART5

116969
ARTC5
ADP-ribosyltransferase 5
protein-coding
11p15.4
Ensembl:ENSG00000167311 MIM:610625 Vega:OTTHUMG00000011842 UniprotKB:Q96L15
NC_000011.10
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.498e-1 (AD)  3.946e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANXA30.454
ART10.448
RAMP20.448
ABCG20.447
OCLN0.443
ST8SIA60.429
PAQR50.428
NEK50.427
LSR0.422
LEF10.407

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HDGFL1-0.248
CES5A-0.244
SLN-0.241
FETUB-0.23
CXCL11-0.225
FIGLA-0.223
FCAMR-0.223
TPTE2-0.222
EFCAB1-0.221
NAT16-0.219

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ART5 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ART5 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of ART5 mRNA17562736
C014949acetylhydrazineacetylhydrazine results in decreased expression of ART5 mRNA15282401
D020106AcrylamideAcrylamide results in decreased expression of ART5 mRNA28959563
D000643Ammonium ChlorideAmmonium Chloride affects the expression of ART5 mRNA16483693
C547126AZM551248AZM551248 results in decreased expression of ART5 mRNA22323515
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ART5 mRNA22228805
D004958EstradiolEstradiol results in decreased expression of ART5 mRNA23019147
C006780bisphenol Abisphenol A results in decreased expression of ART5 mRNA25181051
C018475butyraldehydebutyraldehyde results in increased expression of ART5 mRNA26079696
D002220CarbamazepineCarbamazepine affects the expression of ART5 mRNA25979313
D003042CocaineCocaine results in increased expression of ART5 mRNA17898221
D003300CopperCopper deficiency results in increased expression of ART5 mRNA26033743
D019327Copper SulfateCopper Sulfate results in decreased expression of ART5 mRNA19549813
D003471CuprizoneCuprizone results in decreased expression of ART5 mRNA26577399|2752363
D003561CytarabineCytarabine results in decreased expression of ART5 mRNA21198554
C010902decabromobiphenyl etherdecabromobiphenyl ether affects the expression of ART5 mRNA24834073
D003907DexamethasoneDexamethasone results in increased expression of ART5 mRNA22733784
D003907DexamethasoneDexamethasone results in increased expression of ART5 mRNA20032058
D003907DexamethasoneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ART5 mRNA]20032058
D003976DiazinonDiazinon results in increased methylation of ART5 gene22964155
D004041Dietary FatsDietary Fats results in increased expression of ART5 mRNA18042831
D019422Dietary SucroseDietary Sucrose results in increased expression of ART5 mRNA26033743
D0151279,10-Dimethyl-1,2-benzanthracene"9,10-Dimethyl-1,2-benzanthracene results in decreased expression of ART5 mRNA"22485181
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ART5 mRNA17942748
C004312glycidolglycidol results in decreased expression of ART5 mRNA24915197
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of ART5 mRNA26752646
D000073878Palm OilPalm Oil results in increased expression of ART5 mRNA18042831
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ART5 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of ART5 mRNA26272509
D011374ProgesteroneProgesterone results in decreased expression of ART5 mRNA19690047
D011441PropylthiouracilPropylthiouracil results in decreased expression of ART5 mRNA24780913
D012822Silicon DioxideSilicon Dioxide analog affects the expression of ART5 mRNA25895662
D053260SootSoot results in increased expression of ART5 mRNA26551751
D013739TestosteroneTestosterone inhibits the reaction [Dexamethasone results in increased expression of ART5 mRNA]20032058
C009495titanium dioxidetitanium dioxide results in decreased expression of ART5 mRNA23557971
D014635Valproic AcidValproic Acid affects the expression of ART5 mRNA25979313
D014635Valproic AcidValproic Acid results in increased methylation of ART5 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003950NAD+ ADP-ribosyltransferase activity-IBA21873635  
GO:0003950NAD+ ADP-ribosyltransferase activity-IEA-  
GO:0003953NAD+ nucleosidase activity-IEA-  
GO:0003956NAD(P)+-protein-arginine ADP-ribosyltransferase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006471protein ADP-ribosylation-IBA21873635  
GO:0006471protein ADP-ribosylation-IEA-  
GO:0018120peptidyl-arginine ADP-ribosylation-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-IEA-  
GO:0016020membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
16627471ADP-ribosyltransferase-specific modification of human neutrophil peptide-1. (2006 Jun 23)Paone GJ Biol Chem