Gene: LYZL2

119180
LYZD2
lysozyme like 2
protein-coding
10p11.23
Ensembl:ENSG00000151033 MIM:612748 Vega:OTTHUMG00000017898 UniprotKB:Q7Z4W2
NC_000010.11
PubMed
0   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.072e-1 (AD)  2.360e-1 (ND)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR10J10.619
LCE4A0.574
OR4C110.561
UGT1A10.55
C12orf740.544
OR4K50.54
OR5H10.539
SULT1C30.539
OR4Q30.537
OR4K150.536

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
GDF10-0.274
MKX-0.267
NKRF-0.262
RFPL2-0.26
SATL1-0.255
ZC2HC1C-0.255
HSPA4L-0.253
SPATA5L1-0.253
ZSWIM3-0.251
SLC39A14-0.248

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of LYZL2 gene28458013
C043243methyl tert-butyl ethermethyl tert-butyl ether affects the expression of LYZL2 mRNA24128854
D019287Zinc SulfateZinc Sulfate results in increased expression of LYZL2 mRNA16330358

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0050829defense response to Gram-negative bacterium-IBA21873635  
GO:0050830defense response to Gram-positive bacterium-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24702466Clinical application of genetics to guide prevention and treatment of oral diseases. (2014 Jul)Kornman KSClin Genet